Journals / MN Oftalmoloji / 2000 / Cilt: 7 - Sayı: 3

Assessment of retinal nerve fiber layer with scanning laser polarimetry in glaucoma and glaucoma suspect patients

Glokom hastalarında ve glokom şüpheli olgularda sinir lifi tabakasının tarayıcı laser polarimetre ile incelenmesi

Pages
247–251
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Patients suspected of having glaucoma because of the disc appearance could be advised to be followed with certain intervals (e.g. 6 months) for the assessment of RNFL thickness.

📌 3 Key Takeaways

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Objective & Hypothesis:PURPOSE: to detect the changes in retinal nerve fiber layer (RNFL) in glaucoma suspects and in patients with glaucoma by using the Nerve Fiber Analyzer (NFA).
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Key Findings & Data:METHODS: RNFL thickness measurement with NFA-I was performed in 266 eyes of 218 patients (133 healthy eyes, 80 eyes with glaucoma, and 53 eyes of glaucoma suspects) who applied to Ophthalmology department in Gazi University School of Medicine with different complaints, ages ranging from 16 to 83.
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Conclusion & Impact:Patients suspected of having glaucoma because of the disc appearance could be advised to be followed with certain intervals (e.g. 6 months) for the assessment of RNFL thickness.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Tanı teknikleri · oftalmolojik · Glokom

Abstract

PURPOSE: to detect the changes in retinal nerve fiber layer (RNFL) in glaucoma suspects and in patients with glaucoma by using the Nerve Fiber Analyzer (NFA). METHODS: RNFL thickness measurement with NFA-I was performed in 266 eyes of 218 patients (133 healthy eyes, 80 eyes with glaucoma, and 53 eyes of glaucoma suspects) who applied to Ophthalmology department in Gazi University School of Medicine with different complaints, ages ranging from 16 to 83. RESULTS: The mean RNFL thickness in glaucoma patients was 18.4% and 14.6% less than that in the control group in superior and inferior regions, respectively. Simple regression analysis of RNFL measurements has shown that there was a moderate correlation with mean defect in visual field and no significant correlation with cup-to disc ratio in optic nerve head. The mean RNFL thickness in glaucoma suspects, on the other hand, was somewhere between the control group and the glaucoma group. CONCLUSIONS: Although the RNFL thickness in glaucoma patients is significantly less than that in normals, NFA-I is not suitable for glaucoma screening studies because of an important degree of overlapping with healthy subjects. Patients suspected of having glaucoma because of the disc appearance could be advised to be followed with certain intervals (e.g. 6 months) for the assessment of RNFL thickness.

Özet

AMAÇ: Çalışmamızda sinir lifi analizatörü (NFA) kullanılarak glokom hastalarında ve glokom şüpheli olgularda retina sinir lifi tabakasındaki (RSLT) değişikliklerin belirlenmesi amaçlanmıştır. GEREÇ VE YÖNTEM: Bu çalışmada çeşitli nedenlerle Gazi Üniversitesi Tıp Fakültesi Göz Hastalıkları Polikliniğine başvuran ve yaşları 16 ila 83 arasında değişen toplam 218 hastanın 266 gözünde (133 sağlıklı, 80 glokomatöz ve 53 disk görünümü nedeniyle glokom şüpheli gözde) RSLT kalınlık ölçümü NFA-I kullanılarak yapılmıştır. BULGULAR: Glokom olgularında ortalama RSLT kalınlığının, kontrol grubuna oranla superiorda %18.7, inferiorda %14.6 oranında daha az olduğu, basit regresyon analizinde, görme alanındaki ortalama defekt ile orta derecede korelasyon gösterirken, papilladaki çukur/disk oranı ile anlamlı bir korelasyon göstermediği belirlenmiştir. Glokom şüpheli olgulardaki RSLT kalınlığı ise kontrol grubundan az, glokom olgularından ise fazla olacak şekilde iki grup arasında yer almıştır. SONUÇ: Glokom olgularında sağlıklı insanlara oranla RSLT kalınlığı önemli derecede azalmış olmakla birlikte, belirgin bir örtüşme gösterdiğinden, NFA-I'in glokom tarama testi olarak kullanılması uygun değildir. Disk görünümü nedeniyle glokom şüpheli kabul edilen olguların ise belirli aralıklarla (or:6 ayda bir) RSLT kalınlık ölçümleri ile takip edilmeleri uygun olacaktır.

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Cite This Article

ÖZDEK, Ş. C., ÖNOL, M., HASANREİSOĞLU, B. (2000). Assessment of retinal nerve fiber layer with scanning laser polarimetry in glaucoma and glaucoma suspect patients. MN Oftalmoloji, Cilt: 7 - Sayı: 3, 247–251. https://ajindex.com/articles/296469

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