Journals / MN Oftalmoloji / 2004 / Cilt: 11 - Sayı: 4

Melanocytoma of the optic nerve head: Findings on clinical examination and magnetic resonance imaging

Optik sinir başında melanositoma: Klinik ve manyetik rezonans görüntüleme bulguları

Pages
346–350
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This technique may be advantageous over ultrasonography to document the retrolaminar extension of the tumor especially in patients who demonstrate tumor growth

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Three patients diagnosed with melanocytoma of the optic nerve head underwent detailed ophthalmological examination and were evaluated further with fundus photography, visual fields, visual evoked response, intravenous fluorescein angiography, ultrasonography, and magnetic resonance imaging.
📊
Key Findings & Data:The presence and the retrolaminar extension of the pigmented tumor in the optic nerve were clearly demonstrated in one patient with magnetic resonance imaging.
💡
Conclusion & Impact:This technique may be advantageous over ultrasonography to document the retrolaminar extension of the tumor especially in patients who demonstrate tumor growth
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Optik disk · Manyetik rezonans görüntüleme · Optik sinir neoplazmları

Abstract

Three patients diagnosed with melanocytoma of the optic nerve head underwent detailed ophthalmological examination and were evaluated further with fundus photography, visual fields, visual evoked response, intravenous fluorescein angiography, ultrasonography, and magnetic resonance imaging. The presence and the retrolaminar extension of the pigmented tumor in the optic nerve were clearly demonstrated in one patient with magnetic resonance imaging. Subtle imaging findings suggestive of optic nerve infiltration were detected in another. Magnetic resonance imaging failed to show the tumor in the third. Melanocytoma of the optic nerve head can be detected with magnetic resonance imaging despite the small size of the tumor. This technique may be advantageous over ultrasonography to document the retrolaminar extension of the tumor especially in patients who demonstrate tumor growth

Özet

Optik sinir başında melanositoma tanısı alan üç olguya ayrıntılı göz muayenesinin yanısıra görme alanı, görsel uyarılı potansiyeller, fundus resimlemesi, fundus floresein anjiyografi, ultrasonografi ve manyetik rezonans görüntüleme tetkikleri uygulandı. Bir olguda optik sinir içinde tümör varlığı ve lamina kribroza arkasına uzanımı manyetik rezonans görüntüleme tetkikinde belirgin olarak gösterildi. Kalan iki olgunun birinde optik sinir infiltrasyonunu düşündürebilecek çok belirgin olmayan bulgular saptandı; üçüncü olguda tümör manyetik rezonans görüntülemede gösterilemedi. Küçük boyutlara sahip olmasına rağmen optik sinir başında melanositoma manyetik rezonans görüntüleme ile gösterilebilir. Bu teknik, özellikle tümör büyümesi gözlenen olgularda, optik sinir içine yayılımın gösterilmesinde ultrasonografiye oranla daha faydalı olabilir.

🔖

Cite This Article

MEN, G., ACAROĞLU, G., MEN, S., ÖZALP, S., ÖZKAN, S. S., TACAL, T. (2004). Melanocytoma of the optic nerve head: Findings on clinical examination and magnetic resonance imaging. MN Oftalmoloji, Cilt: 11 - Sayı: 4, 346–350. https://ajindex.com/articles/296084

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Zimmerman LE. Melanocytes, melanocytic nevi, and melanocytoma. Invest Ophthalmol Vis Sci 1965; 4:11-41
  2. Joffe L, Shields JA, Osher RH, Gass JD. Clinical and followup studies of melanocytomas of the optic disc. Ophthalmology 1979; 86:1067-83
  3. Leidenix M, Mamalis N, Goodart R, Harrie R, Kjeldsberg C. Malignant transformation of a necrotic melanocytoma of the choroid in an amblyopic eye. Ann Ophthalmol 1994; 26:42-6
  4. Meyer D, Ge J, Blinder KJ, Sinard J, Xu S. Malignant transformation of an optic disc melanocytoma. Am J Ophthalmol 1999; 127:710-4
  5. Erzurum SA, Jampol LM, Territo C, O'Grady R. Primary malignant melanoma of the optic nerve simulating a melanocytoma. Arch Ophthalmol 1992; 110:684-6
  6. De Potter P, Shields CL, Eagle RC Jr, Shields JA, Lipkowitz JL. Malignant melanoma of the optic nerve. Arch Ophthalmol 1996; 114:608-12
  7. Usui T, Shirakashi M, Kurosawa A, Abe H, Iwata K. Visual disturbance in patients with melanocytoma of the optic disc. Ophthalmologica 1990; 201:92-8
  8. Shuey TF, Blacharski PA. Pigmented tumor and acute visual loss. Surv Ophthalmol 1988; 33:121-6
  9. Shields CL, Santos MC, Shields JA, Singh AD, Eagle RC Jr. Extraocular extension of unrecognized choroidal melanoma simulating a primary optic nerve tumor: report of two cases. Ophthalmology 1999; 106:1349-52
  10. Wilms G, Marchal G, Van Fraeyenhoven L, et al. Shortcomings and pitfalls of ocular MRI. Neuroradiology 1991; 33:320-5
  11. Shields JA, Shields CL, Eagle RC Jr, Singh AD, Berrocal MH, Berrocal JA. Central retinal vascular obstruction secondary to melanocytoma of the optic disc. Arch Ophthalmol 2001; 119:129-33
  12. Osher RH, Shields JA, Layman PR. Pupillary and visual field evaluation in patients with melanocytoma of the optic disc. Arch Ophthalmol 1979; 97:1096-9
  13. Takahashi T, Isayama Y, Okuzawa I. Unusual case of melanocytoma in optic disk. Jpn J Ophthalmol 1984; 28:171-5
  14. Yu M, Brown B, Edwards MH. Investigation of multifocal visual evoked potential in anisometropic and esotropic amblyopes. Invest Ophthalmol Vis Sci 1998; 39:2033-40.