Journals / MN Oftalmoloji / 2006 / Cilt: 13 - Sayı: 2

Sodium, potassium, magnesium, calcium, iron and zinc concentrations in human mature cataractous lenses

Matür kataraktlı lenslerde sodyum potasyum, magnezyum, kalsiyum, demir ve çinko içeriği

Pages
91–93
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These results support the hypothesis that the element levels as in our study may contribute to cataract formation.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: The purpose of the study was to asses the sodium, potassium, magnesium, calcium, iron, and zinc contents of human mature cataractous lenses.
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Key Findings & Data:Material and Methods: The determination of the elements was performed by atomic absorption spectrometry in 49 mature cataractous human lenses to whom performed extracapsular cataract extraction (ECCE).
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Conclusion & Impact:These results support the hypothesis that the element levels as in our study may contribute to cataract formation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Lens · kristalin · Kalsiyum

Abstract

Purpose: The purpose of the study was to asses the sodium, potassium, magnesium, calcium, iron, and zinc contents of human mature cataractous lenses. Material and Methods: The determination of the elements was performed by atomic absorption spectrometry in 49 mature cataractous human lenses to whom performed extracapsular cataract extraction (ECCE). Results compared with those in clear lens which reported in the literature. Results: Mean±SD sodium, potassium, magnesium, calcium, iron, and zinc concentrations were found the mean±SD as 17653±10077, 1079.8±525.9, 681.8±387.5, 214.5±47.5, 63.7±19.9, 28.5±17.3 µg/g (dry weight), respectively. Sodium, calcium and iron levels were significantly higher, and that of potassium levels were significantly lower in mature cataractous lenses than those in clear human eye lenses (p<0.05). No statistically significant differences were found for the concentrations of magnesium and zinc (p>0.05). Conclusion: In the mature cataractous human lenses the concentrations of sodium, calcium and iron were higher, while potassium levels were lower and magnesium and zinc levels were not different. These results support the hypothesis that the element levels as in our study may contribute to cataract formation.

Özet

Amaç: Matür kataraktlı olguların lenslerinde sodyum, potasyum, magnezyum, kalsiyum, demir ve çinko elementlerinin ölçülmesi. Gereç ve Yöntem: Matür katarakt nedeni ile ekstra kapsüler katarakt ekstraksiyonu yapılan 49 olgunun lenslerinde sodyum, potasyum, magnezyum, kalsiyum, demir ve çinko elementlerinin miktarı atomik absorbsiyon yöntemi ile saptandı. Sonuçlar literatürdeki saydam lens sonuçları ile karşılaştırıldı. Bulgular: Sodyum, potasyum, magnezyum, kalsiyum, demir, ve çinko konsantrasyonları sırasıyla ortalama±SD 17653±10077, 1079.8±525.9, 681.8±387.5, 214.5±47.5, 63.7±19.9, 28.5±17.3 µg/g (kuru ağırlık) idi. Saydam lens sonuçları ile karşılaştırıldığında kataraktlı lenslerde sodyum, kalsiyum ve demir elementlerinin miktarlarının istatistiksel olarak daha yüksek, potasyum elementinin miktarının ise istatistiksel olarak daha düşük olduğu saptandı (p 0.05). Sonuç: Matür kataraktlı lenslerde kalsiyum, sodyum ve demir elementlerinin miktarlarının arttığı, potasyum elementinin miktarının azaldığı, magnezyum ve çinko elementlerinin miktarlarının değişmediği saptandı. Bu bulgular lens element içeriğindeki değişimlerin katarak gelişimine katkıda bulunduğu hipotezini desteklemektedir.

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Cite This Article

ÇAÇA, İ., DÜZ, T., ÜNLÜ, K., AYATA, A., ARI, Ş. (2006). Sodium, potassium, magnesium, calcium, iron and zinc concentrations in human mature cataractous lenses. MN Oftalmoloji, Cilt: 13 - Sayı: 2, 91–93. https://ajindex.com/articles/296001

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References (14)

  1. Rasi V, Costantini S, Moramarco A, Giordano R, Giustolisi R, Balacco Gabrieli C. Inorganic element concentrations in cata ractous human lenses. Ann Ophthalmol 1992; 24:459-64
  2. Garland D. Role of site-specific, metal-catalyzed oxidation in lens aging and cataract: a hypothesis. Exp Eye Res 1990; 50:677-82
  3. Stanojevic-Faovic A, Hristic V, Cuperlovic M, Jovanovic S, Krsmanovic J. Macro and microelements in the cataractous eye lens. Ophthalmic Res 1987; 19:230-4
  4. Hou X, Hou Y. Determination of 19 elements in human eye lenses. Biol Trace Elem Res 1996; 55:89-98
  5. Shukla N, Moitra JK, Trivedi RC. Determination of lead, zinc, potassium, calcium, copper and sodium in human cataract lenses. Sci Total Environ 1996; 181:161-5
  6. Srivastava VK, Varshney N, Pandey DC. Role of trace ele ments in senile cataract. Acta Ophthalmol 1992; 70:839-41
  7. Gunduz G, Gunduz F, Yucel I, Senturk UK. Levels of zinc and magnesium in senile and diabetic senile cataractous lenses. Biol Trace Elem Res 2003; 95:107-12
  8. Bonting SL. NA-K Activated adenosinetriphosphatase and active cation transport in the lens. Invest Ophthalmol 1965; 44:723-44
  9. Fukui HN, Merola LO, Kinoshita JH. A possible cataractogenic factor in the Nakano mouse lens. Exp Eye Res 1978; 26:477-85
  10. Marcantonio JM, Duncan G, Davies PD, Bushell AR. Classification of human senile cataracts by nuclear colour and sodium content. Exp Eye Res 1980; 31:227-37
  11. Hightower KR, Reddy VN. Metabolic studies on calcium transport in mammalian lens.Curr Eye Res 1981; 1:197-204
  12. Hightower KR, Reddy VN. Ca++-induced cataract. Invest Ophthalmol Vis Sci 1982; 22:263-7
  13. Giordana R, Constantini S. Metals in cataractous human lenses. Microchem J 1992; 46:184-90
  14. Hockwin O, Laser H, De Gregorio M, Carrieri MP. Bendazac lysine in selected types of human senile cataract. A long- term double-masked placebo-controlled clinical trial with multilinear densitometric image analysis of Scheimpflug photographs. Ophthalmic Res 1989; 21:141-54.