Journals / MN Oftalmoloji / 2007 / Cilt: 14 - Sayı: 2

Clinical features of thyroid ophthalmopathy in pediatric patients

Pediatrik yaş grubunda tiroid oftalmopatinin klinik özellikleri

Pages
125–127
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Treatment is infrequently necessary.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: To evaluate the clinical characteristics of thyroid ophthalmopathy in children Methods: Medical records of six patients with thyroid ophthalmopathy who were 18 years old or younger were evaluated retrospectively.
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Key Findings & Data:Results: Mean age was 15.5 years (range 13 to 18 years).
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Conclusion & Impact:Treatment is infrequently necessary.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Geriyedönük çalışma · Graves oftalmopati · Ergen

Abstract

Aim: To evaluate the clinical characteristics of thyroid ophthalmopathy in children Methods: Medical records of six patients with thyroid ophthalmopathy who were 18 years old or younger were evaluated retrospectively. Results: Mean age was 15.5 years (range 13 to 18 years). The mean interval between diagnosis of thyroid dysfunction and onset of ophthalmic symptoms was 1.1 years (range 1 month to 3 years). All patients were female. Mean follow-up period was 1.58 year(4 months-4.6 years). Five patients were classified as hyperthyroid, one patient was subclinically hyperthyroid. Foreign body sensation was observed in all patients (100%). In one patient, there were superior limbic keratoconjunktivitis and punctate corneal staining. One patient (16.6%) has conjunctival injection. Bilateral lid-lag was observed in 2 patients (33.3%) and unilateral in 1 patient. Two patients (33.3%) had eyelid retraction. Exophthalmos of 22m or greater was seen in 2 patients (33.3%). Extraocular muscle involvement and diplopia were found in 2 patients (%33.3). In fundoscopic examination, there was no optic neuropathy. None of the patients required surgical or medical treatment except supportive therapy such as topical lubricant and steroids. Conclusion: The clinical manifestations of thyroid ophthalmopathy are relatively less severe in pediatric patients. Treatment is infrequently necessary.

Özet

Amaç: Pediatrik yaş grubundaki hastalarda tiroid oftalmopatinin klinik özeliklerini incelemek. Materyal ve metod: Kliniğimizde takip edilen onsekiz yaş altı tiroid oftalmopati tanısı almış 6 hastanın klinik özellikleri retrospektif olarak değerlendirildi. Bulgular: Hastaların ortalama yaşı 15.5 yıl (13-18 yıl) idi. Tiroid disfonksiyonu ile tiroid oftalmopatinin başlangıcı arasında geçen süre ortalama 1.1yıl (min: 1 ay mak: 3 yıl) idi. Altı hastanın hepsi bayandı (%100). Ortalama takip süresi 1.58 yıl(4 ay-4.6 yıl) idi. Beş hastada hipertiroidi saptanırken, 1 hastada subklinik hipertiroidi mevcuttu. Hastaların hepsinde (%100) yabancı cisim hissi şikayeti olduğu görüldü. Bir hastada (%16.6) üst limbik keratokonjonktivit (ÜLKK) ve yine aynı hastada korneada noktasal epitel defekti saptandı. Bir hastada (%16.6) konjonktivada kızarıklık mevcuttu. ‘Lid-lag’ yönünden hastalar değerlendirildiğinde 1’inde (%16.6) tek taraflı, 2’sinde (%33.3) ise her iki gözde ‘lid- lag’’in mevcut olduğu görüldü. Kapak retraksiyonu 2 (%33.3) hastada gözlendi. İki hastada (%33.3) 22 mm ve üstü egzoftalmi mevcuttu. İki hastada (%33.3) göz dışı kas işlev kusuru mevcuttu.Yine aynı iki hastada çift görme saptandı. Fundoskopide hiç bir hastada optik nöropati bulgusuna görülmedi. Hastalarda yerel lubrikanlar ve steroidler dışında tibbi ve cerrahi tedavi gereksinimi olmadı. Sonuç: Tiroid oftalmopati çocukluk çağında klinik olarak çok daha az şiddetle ortaya çıkar. Bu nedenle tedavi daha az gerektirir.

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Cite This Article

YAMAN, A., KOÇ, T., ÖZBEK, Z., BÖBER, E., BERK, A. T., SÖYLEV, M. F. (2007). Clinical features of thyroid ophthalmopathy in pediatric patients. MN Oftalmoloji, Cilt: 14 - Sayı: 2, 125–127. https://ajindex.com/articles/295975

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References (8)

  1. Graves RJ. Clinical lecture (part II). London Med Surg J 1835;7:516-7
  2. Bram I.Exopthalmic goiter in children: comments based upon 128 ncases in patients of 12 and under. Arch pediatr 1937; 54:419-24. 3.Sindhu K,Downie J,Ghabrial R.Martin F. Aetiology of childhood propîösis. J Paediatr Child Health Aug 1998; 34(4);374-6. 4.Wiersinga WM. Thyroid associated ophthalmopathy: pediatric and endocrine aspect. Pediatr Endocrinol Rev 2004; 1 (suppl 3); 513-17. 5.Young LA. Dysthyroid ophthalmopathy in children. J Pediatr Ophthalmol Srtrabismus 1979;16:105-7. 6.Uretsky SH, Kennerdell JS, Gutai JP. Graves' ophthalmopathy in childhood and adolescence Arch Ophthalmol 1980;98: 1963-4. 7.Durairaj VD, Bartley GB, Garrity JA. Clinical features and treatment of Tiroid ophthalmopathy in pediatric patients Opht¬halmic Plastic and Reconstructive Surgery 2006;22(1): 7-12. 8.Bartalena L, Marrocci C, Bogazzi F, Manetti L, Tanda ML ve ark. Relation between theraphy for hyperthyroidism and the course of Graves' ophthalmopathy. N Eng J Med 1998; 338 (2):73-8
  3. Söylev MF,Özkan SB, Çan D, Kasım R, Duman S. Tiroid oftal mopatide sigara içiminin rolü. MN Oftalmoloji 1995;3:222-4
  4. Tallstedt L, Lundell G, Taube A. Graves ophthalmopathy and tobacco smoking. Açta Endocrinol 1993;129:147-50
  5. Bartley GB, Fatourechi V, Kadrmas ED, Jacobsen SJ, llstrup DM, Garrity JA, Gorman CA. The treatment of Graves'opht halmopathy in an incidence cohort. Am J Ophthalmol 1996;121:200-6
  6. Lui GT, Heher KL, Katowitz JA ve ark. Prominent proptosis in childhood thyroid eye disease. Ophthalmology 1996; 103: 779-84
  7. Nucci P, Brancato R, Bandello F, Alferano R, Bianchi S. Nor mal exopthalmometric values in children. Am J Ophthalmol 1989; 108:582-4
  8. Jackson E. The position of the eyeball in orbit. Trans Sect Ophthalmol Am Med Assoc 1921;27: 58-76.