Journals / MN Oftalmoloji / 2010 / Cilt: 17 - Sayı: 2

Optic neuritis associated with etanercept therapy in a patient with rheumatoid arthritis

Romatoid artritli hastada etanercept tedavisine bağlı optik nörit gelişimi

Pages
127–129
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case, it was aimed to present a patient who had developed optic neuritis due to the use of Etanercept , and treated by 1000mg/day intravenous doses of methyl prednisolone for 5 days and followed by oral steroid after Etanercept therapy immediate termination.

📌 3 Key Takeaways

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Objective & Hypothesis:A 55 year old female patient who applied our ophtalmology clinic with complaint of progressive vision loss in the right eye for three days had table of optic neuritis.
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Key Findings & Data:When the patient questioned about her resume, it was learned that she was a rheumatoid arthritis patient and she had been using Etanercept which was an inhibitor of TNF-α.
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Conclusion & Impact:In this case, it was aimed to present a patient who had developed optic neuritis due to the use of Etanercept , and treated by 1000mg/day intravenous doses of methyl prednisolone for 5 days and followed by oral steroid after Etanercept therapy immediate termination.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kadın · Artrit · romatoid

Abstract

A 55 year old female patient who applied our ophtalmology clinic with complaint of progressive vision loss in the right eye for three days had table of optic neuritis. When the patient questioned about her resume, it was learned that she was a rheumatoid arthritis patient and she had been using Etanercept which was an inhibitor of TNF-α. In this case, it was aimed to present a patient who had developed optic neuritis due to the use of Etanercept , and treated by 1000mg/day intravenous doses of methyl prednisolone for 5 days and followed by oral steroid after Etanercept therapy immediate termination.

Özet

Göz Hastalıkları Polikliniği’ne sağ gözünde üç gündür giderek artan görme azlığı şikayetiyle başvuran 55 yaşındaki bayan hastanın sağ gözünde optik nörit tablosu mevcuttu. Hasta - nın özgeçmişi sorgulandığında Romatoid Artrit hastası olduğu ve bir TNF-α inhibitörü olan Etanercept kullandığı öğrenildi. Bu olgu sunumunda etanercept kullanımına bağlı optik nörit gelişimi sonrasında etanercept tedavisi derhal sonlandırılarak intravenöz yolla 5 gün 1000mg/gün dozunda metilprednizolon ve takibinde oral steroid tedavisi alan bir olgunun sunumu amaçlanmıştır.

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Cite This Article

DURSUN, A., ARICI, M. K., DURSUN, F., TOPALKARA, A., TOKER, M. İ., ÖZEÇ, A. V. (2010). Optic neuritis associated with etanercept therapy in a patient with rheumatoid arthritis. MN Oftalmoloji, Cilt: 17 - Sayı: 2, 127–129. https://ajindex.com/articles/295813

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References (6)

  1. Khanna D, McMahon M, Furst DE. Safety of tumour necrosis factor-alpha antagonists. Drug Saf 2004;27:307-24
  2. Mohan N, Edwards ET, Cupps TR, Oliverio PJ, Sandberg G, Crayton H, et al. Demyelination occurring during anti-tumor necrosis factor alpha therapy for inflammatory arthritides. Arthritis Rheum 2001;44:2862-9. 3 Thomas CW Jr, Weinshenker BG, Sandborn WJ. Demyelination during antitumor necrosis factor alpha therapy with infliximab for Crohn’s disease. Inflamm Bowel Dis 2004;10:28-31. 4 Shin IS, Baer AN, Kwon HJ, Papadopoulos EJ, Siegel JN. Guillain–Barre and Miller Fisher syndromes occurring with tumor necrosis factor alpha antagonist herapy. Arthritis Rheum 2006;54:1429-34. 5 Robinson WH, Genovese MC, Moreland LW. Demyelinating and neurologic events reported in association with tumor necrosis factor alpha antagonism: by what mechanism could tumor necrosis factor alpha antagonists improve rheumatoid arthritis but exacerbate multiple sclerosis? Arthritis Rheum 2001;44:1977-83
  3. Noguera-Pons B, Borras-Blasco J, Romero-Crespo I, Anton- Torres R, Navarro-Ruiz A, Gonzalez-Ferrandez JA. Optic neuritis with concurrent etanercept and isoniazid therapy. Ann Pharmacother 2005; 39: 2131-4
  4. Tauber T, Daniel D, Barash J, Turetz J, Morad Y. Optic neuritis associated with etanercept therapy in two patients with extended oligoarticular juvenile idiopathic arthritis. Rheuma to - logy 2005;44:405
  5. Tauber T, Turetz J, Barash J, Avni I, Morad Y. Optic neuritis associated with etanercept therapy for juvenile arthritis. J AAPOS 2006;10:26-9
  6. Simsek I, Erdem H, Pay S, Sobaci G, Dinc A.Optic neuritis occurring with anti-tumour necrosis factor atherapy. Ann Rheum Dis 2007;66:1255-8.