Journals / MN Oftalmoloji / 2012 / Cilt: 19 - Sayı: 3

Deep anterior lamellar keratoplasty: First 40 cases in our learning curve

Derin anterior lameller keratoplasti: öğrenme eğrimizde ilk 40 vaka

Pages
149–155
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

When we consider these advantages it is a strong alternative in corneal pathologies in which endothelium is healthy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: To report results and complications of first 40 cases which we performed deep anterior lameller keratoplasty.
📊
Key Findings & Data:Material and Method: Forty eyes of 39 patients in whom we performed deep anterior lameller keratoplasty with different indications were included in this retrospective study.
💡
Conclusion & Impact:When we consider these advantages it is a strong alternative in corneal pathologies in which endothelium is healthy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: To report results and complications of first 40 cases which we performed deep anterior lameller keratoplasty. Material and Method: Forty eyes of 39 patients in whom we performed deep anterior lameller keratoplasty with different indications were included in this retrospective study. Deep anterior lamellar keratoplasty was aimed to be performed using big-bubble technique described by Anwar and Teichmann in all cases. If the bubble was not achieved completely, manual dissection was performed to bare Descemet’s membrane. Keratoplasty indications, best corrected visual acuities, refraction and keratometry values, intraocular pressures, pachymetry readings, endothelial cell densities obtained in preoperative and postoperative visits and peroperative and postoperative complications were evaluated. Results: The diagnosis of the patients were keratoconus in 30 patients (75%), corneal scar in 6 patients (15%), corneal dystrophy in 3 patients (7.5%), pellucid marginal degeneration in 1 patient (2.5%). Big bubble was achieved in 24 eyes out of 40 (60%). Descemet membrane perforation occured in 7 patients (17.5%). Allogreft rejection episode was encountered in 1 patient (2.5%) in postoperative period. Mean best corrected visual acuity in postoperative 12th month visit was 0,46±0,18 (0,10-0,80) (n=21). Postoperative mean endothelial cell loss was 10,37±6,31% in 3 months (n=24); 13,88±7,67% in 6 months (n=23); 15,81±8,58% in 9 months (n=21); 19,51±7,51% in 12 months (n=15). Conclusion: Deep anterior lameller keratoplasty presents many important advantages in corneal transplantation. When we consider these advantages it is a strong alternative in corneal pathologies in which endothelium is healthy.

Özet

Amaç: Derin anterior lameller keratoplasti uygulanan ilk 40 vakanın bulgularını ve komplikasyonlarını bildirmek. Gereç ve Yöntem: Farklı tanılarla derin anterior lameller keratoplasti yapılan ilk 39 hastanın 40 gözü geriye dönük olarak yapılan bu çalışmaya dahil edildi. Bütün cerrahilerde derin anterior lameller keratoplastinin Anwar ve Teichmann’ın tarif ettiği şekilde büyük hava kabarcığı tekniği ile uygulanması hedeflendi. Hastaların keratoplasti endikasyonları, ameliyat öncesi ve sonrası takiplerde en iyi düzeltilmiş görme keskinlikleri, refraksiyon ve keratometri değerleri, göz içi basınçları, pakimetri değerleri, endotel hücre yoğunlukları, ameliyat sırasında ve sonrasında karşılaşılan komplikasyonlar değerlendirildi. Bulgular: Hastaların tanıları 30 hastada keratokonus (%75), 6 hastada kornea skarı (%15), 3 hastada kornea distrofisi (%7,5), 1 hastada pellusid marjinal deje ne ras yon (%2,5) idi. Ameliyat sırasında 40 gözün 24’ünde (%60) büyük hava kabarcığı oluşturulabildi. Yedi hastada (%17,5) Descemet membranı perforasyonu gelişti. Ameliyat sonrasında 1 hastada (%2,5) allogreft reddi atağı gelişti. Hastaların ortalama en iyi düzeltilmiş görme keskinlikleri ameliyat sonrası 12. ayda 0,46±0,18 (0,10-0,80) (n=21) idi. Hastaların ortalama endotel hücre kaybı ilk 3 ayda %10,37±6,31 (n=24); 6 ayda %13,88±7,67 (n=23); 9 ayda %15,81±8,58 (n=21); 12 ayda %19,51±7,51 (n=15)idi. Sonuç: Derin anterior lameller keratoplasti kornea transplantasyonunda çok önemli avantajlar sunmaktadır ve bu avantajlar göz önüne alındığında, endotelin sağlıklı olduğu kornea patolojilerinde penetran keratoplastiye güçlü bir alternatiftir.

🔖

Cite This Article

BAHADIR, A. E., BOZKURT, T. K., TORUN, B. A., AKTAY, S. K., ACAR, S. (2012). Deep anterior lamellar keratoplasty: First 40 cases in our learning curve. MN Oftalmoloji, Cilt: 19 - Sayı: 3, 149–155. https://ajindex.com/articles/295752

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Niederkorn JY. Immune mechanisms of corneal allograft rejection. Curr Eye Res 2007;32:1005-16
  2. Klebe S, Coster DJ, Williams KA. Rejection and acceptance of corneal allografts. Curr Opin Organ Transplant 2009;14:4-9
  3. Kirkness CM, Ficker LA, Steele AD, Rice NS. The success of penetrating keratoplasty for keratoconus. Eye 1990;4:673-88
  4. Melles GRJ, Deep Anterior Lamellar Keratoplasty In Reinhard T, Larkin P. ed.Cornea and External Eye Disease The Netherlands: Springer 2006; 65-71
  5. Danasoury AE, Hashem A. Deep lamellar keratoplasty with baring of Descemet membrane: the big bubble technique Techniques in Ophthalmology 2007;5:56-62
  6. Trimarchi F, Poppi E, Klersy C, Piacentini C. Deep lamellar keratoplasty. Ophthalmologica 2001;215:389-93
  7. Sugita J, Kondo J. Deep lamellar keratoplasty with complete removal of pathological stroma for vision improvement. Br J Ophthalmol 1997;81:184-8
  8. Al-Torbak A, Malak M, Teichmann KD, Wagoner MD. Presumed stromal graft rejection after deep anterior lamellar keratoplasty. Cornea 2005;24:241-3
  9. Saini JS, Jain AK, Sukhija J, Saroha V. Indications and outcome of optical partial thickness lamellar keratoplasty. Cornea 2003;22:111-3
  10. Han DC, Mehta JS, Por YM, Htoon HM, Tan DT. Comparison of outcomes of lamellar keratoplasty and penetrating keratoplasty in keratoconus. Am J Ophthalmol 2009;148:744-51 e1
  11. Tan DT, Mehta JS. Future directions in lamellar corneal transplantation. Cornea 2007;26(Suppl 1):S21-8
  12. Alio JL, Shah S, Barraquer C, Bilgihan K, Anwar M, Melles GR. New techniques in lamellar keratoplasty. Curr Opin Ophthalmol 2002;13:224-9
  13. Vajpayee RB, Tyagi J, Sharma N, Kumar N, Jhanji V, Titiyal Kaynaklar Bahadır AE. Bozkurt TK. Torun Acar B. Aktay Kutan S. Acar S. JS. Deep anterior lamellar keratoplasty by big-bubble technique for treatment corneal stromal opacities. Am J Ophthalmol 2007;143:954-7
  14. Funnell CL, Ball J, Noble BA. Comparative cohort study of the outcomes of deep lamellar keratoplasty and penetrating keratoplasty for keratoconus. Eye 2006;20:527-32
  15. Watson SL, Ramsay A, Dart JK, Bunce C, Craig E. Comparison of deep lamellar keratoplasty and penetrating keratoplasty in patients with keratoconus. Ophthalmology 2004;111:1676-82
  16. Fontana L, Parente G, Tassinari G. Clinical outcomes after deep anterior lamellar keratoplasty using the big-bubble technique in patients with keratoconus. Am J Ophthalmol 2007;143:117-24
  17. Lim L, Pesudovs K, Coster DJ. Penetrating keratopl