SavedAdd your journal

Journals / MN Oftalmoloji / 2014 / Cilt: 21 - Sayı: 3

Evaluation of macular thickness and retinal nerve fiber layer with optical coherence tomography in adult patients with anisometropic amblyopia

Anizometropik ambliyop erişkin olgularda maküla kalınlığı ve retina sinir lifi tabakasının optik koherans tomografi ile değerlendirilmesi

Halil Hüseyin ÇAĞATAY
Metin EKİNCİ
Yaran KOBAN
Emre İstiklal DURGUNLU
Zeliha YAZAR
Pages
201–206
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: In our study, mean foveal volume (central-parafoveal-perifoveal), central foveal thickness and RNFL thickness did not differ significantly between the eyes of adult pa- tients with unilateral anisometropic amblyopia.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: To compare the central foveal thickness, foveal volume and retinal nerve fiber layer (RNFL) thicknesses of amblyopic and sound eyes in adult patients with unilateral ani- sometropic amblyopia.
📊
Key Findings & Data:Results: 41 patients were included in the study.
💡
Conclusion & Impact:Conclusion: In our study, mean foveal volume (central-parafoveal-perifoveal), central foveal thickness and RNFL thickness did not differ significantly between the eyes of adult pa- tients with unilateral anisometropic amblyopia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: To compare the central foveal thickness, foveal volume and retinal nerve fiber layer (RNFL) thicknesses of amblyopic and sound eyes in adult patients with unilateral ani- sometropic amblyopia. Material and Method: In this prospective randomised study, adult patiens with unilateral anisometropic amblyopia were included. Central macular thickness, foveal volume and RNFL thickness of each eye was measured by OCT. Results were statistically analyzed between the amblyopic and fellow eyes. Results: 41 patients were included in the study. The average age of the patients was 34.0±13.2 (range 21 to 54) years and male /female ratio was 1:1. Mean best-corrected visual acuity (BCVA) was 0.45±0.19 (range, 0.1 to 0.7) in the amblyopic eyes and 1.0±0.00 in the sound eyes. The average central macular thickness, foveal volume and peripapillary RNFL thickness in the sound eyes were 241.32±24.91μm, 0.19±0.02 mm3 ve 108.64±14.29μm re- spectively. The average central macular thickness, foveal volume and peripapillary RNFL thickness in the amblyopic eyes were 247.00±27.13μm, 0.19±0.02 mm3 ve 107.50±14.47 re- spectively. Conclusion: In our study, mean foveal volume (central-parafoveal-perifoveal), central foveal thickness and RNFL thickness did not differ significantly between the eyes of adult pa- tients with unilateral anisometropic amblyopia.

Özet

Amaç: Tek taraflı anizometropik ambliyopisi olan erişkin hastaların ambliyop gözleri ile sağlam gözlerinin, merkezi fovea kalınlığı (MFK), fovea hacmi (FH) ve retinal sinir lifi taba- kası (RSLT) kalınlığı değerlerinin karşılaştırılması. Gereç ve Yöntem: Bu prospektif randomize çalışmaya tek taraflı anizometropik ambliyo- pisi bulunan erişkin hastalar alındı. Tüm olguların MFK, FH ve RSLT kalınlığı ölçüldü. Bu parametrelerin ortalama değerleri, hastaların ambliyop gözleri ile sağlam olan diğer gözleri arasında karşılaştırılarak istatistiksel analizleri yapıldı. Bulgular: Çalışmaya 41 hasta dahil edildi. Ortalama yaş 34,0±13,2 (21-54) yıl, kadın/ er- kek oranı 1:1 idi. Sağlam gözlerde en iyi düzeltilmiş görme keskinliği EİDGK ortalaması Snellen eşeline göre 1,0±0,00, ambliyop gözlerde 0.45±0.19 (0.1-0.7) saptandı. Olguların sağ- lam gözlerinde MFK ortalaması, FH ortalaması ve RSLT kalınlığı ortalaması sırasıyla 241,32±24,91 μm, 0.19±0,02 mm3 ve 108,64±14,29 μm olarak tespit edildi. Ambliyop gözlerin bu değerleri sırasıyla 247,00±27,13 μm, 0.19±0,02 mm3 ve 107,50±14,47 μm bulundu. Sonuç: Çalışmamızda bir gözü sağlam, diğer gözü anizometropik ambliyop olan yetişkin- lerde MFK, FH (santral-parafoveal-perifoveal) ve RSLT kalınlığı ortalama değerleri açısın- dan istatistiksel olarak anlamlı fark tespit edilmedi (p>0,05).

🔖

Cite This Article

ÇAĞATAY, H. H., EKİNCİ, M., KOBAN, Y., DURGUNLU, E. İ., YAZAR, Z. (2014). Evaluation of macular thickness and retinal nerve fiber layer with optical coherence tomography in adult patients with anisometropic amblyopia. MN Oftalmoloji, Cilt: 21 - Sayı: 3, 201–206. https://ajindex.com/articles/295691

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Attebo K, Mitchell P, Cumming R, Smith W, Jolly N, Sparkes R. Prevalence and causes of amblyopia in an adult popula- tion. Ophthalmology 1998;105:154-9
  2. Caputo R, Frosini R, De LC, Campa L, Magro EF, Secci J. Factors influencing severity of and recovery from ani- sometropic amblyopia. Strabismus 2007;15:209-14
  3. Holmes JM, Kraker RT, Beck RW, et al. A randomized trial of prescribed patching regimens for treatment of severe ambly- opia in children. Ophthalmology 2003;110:2075-87
  4. Holmes JM, Beck RW, Kraker RT, et al. Impact of patching and atropine treatment on the child and family in the ambly- opia treatment study. Arch Ophthalmol 2003;121:1625-32
  5. Friedman DS, Repka MX, Katz J, et al. Prevalence of ambly- opia and strabismus in white and African American children aged 6 through 71 months the Baltimore Pediatric Eye Disease Study. Ophthalmology 2009;116:2128-34
  6. Groenewoud JH, Tjiam AM, Lantau VK, et al. Rotterdam Amblyopia Screening Effectiveness Study: detection and causes of amblyopia in a large birth cohort. Invest Ophthalmol Vis Sci doi: 10.1167/iovs.08-3352
  7. Bradley A, Freeman RD Contrast sensitivity in anisometropic amblyopia. Invest Ophthalmol Vis Sci 1981;21:467-76
  8. Hess RF, Thompson B, Gole G, Mullen KT. Deficient re- sponses from the lateral geniculate nucleus in humans with amblyopia. Eur J Neurosci 2009;29:1064-70
  9. Li X, Mullen KT, Thompson B, Hess RF. Effective connectivity anomalies in human amblyopia. Neuroimage 2011;54:505- 16
  10. Miki A, Liu GT, Goldsmith ZG, Liu CS, Haselgrove JC. Dec- reased activation of the lateral geniculate nucleus in a patient with anisometropic amblyopia demonstrated by functional magnetic resonance imaging. Ophthalmologica 2003;217: 365-9
  11. Russell EL, Kada JM, Hufhines DM. Orange County vision screening project. Ophthalmologic evaluation. Sight Saving Rev 1961;31:215-9
  12. Chow KL. Failure to demonstrate changes in the visual sys- tem of monkeys kept in darkness or colored light. J Comp Neurol 1955;102:597-606
  13. Yazici AT, Malkoç I, Altunkaynak BZ, et al. Number of axons in the right and left optic nerves of right-pawed and left-pawed rats: a stereologic study. Anal Quant Cytol Histol 2009;31: 177-83
  14. Enoch JM. Receptor amblyopia. Am J Ophthalmol 1959; 48:262-74
  15. Yen MY, Cheng CY, Wang AG. Retinal nerve fiber layer thick- ness in unilateral amblyopia. Invest Ophthalmol Vis Sci 2004; 45:2224-30
  16. Dickmann A, Petroni S, Salerni A, Dell'Omo R, Balestrazzi E. Unilateral