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Journals / MN Oftalmoloji / 2014 / Cilt: 21 - Sayı: 3

Comparison of retinal nerve fiber layer thicknesses measured with rtvue 100 in glaucomatous and nonglaucomatous cases

Glokomatöz ve non-glokomatöz olgularda rtvue 100 ile ölçülen gangliyon hücre kompleksi ve retina sinir lifi tabakası kalınlıklarının karşılaştırılması

Zeynep AKTAŞ
Fulya YAYLACIOĞLU
Filiz ÖZDEMİR AVŞİN
CELAL MURAT HASANREİSOĞLU
Sefer Ogün BÖLÜK
Sadık KAVAKLI
Pages
179–184
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: As a new generation optical coherence tomography, using RTVue 100 is ad- vantageous by means of its ability to measure GCC in addition to RNFL thickness in glauco- matous patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: To compare the gangliyon cell complex (GCC) between glaucomatous and non-glau- comatous eyes measured by RTVue 100 (Optovue) and evaluate the relationship between this parameter and retinal nerve fiber (RNFL) thickness parameters.
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Key Findings & Data:Material and Method: 43 eyes of 43 primary open angle glaucoma and pseudoexfoliation glaucoma patients and 46 eyes of the 46 healthy controls were included in the study.
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Conclusion & Impact:Conclusion: As a new generation optical coherence tomography, using RTVue 100 is ad- vantageous by means of its ability to measure GCC in addition to RNFL thickness in glauco- matous patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: To compare the gangliyon cell complex (GCC) between glaucomatous and non-glau- comatous eyes measured by RTVue 100 (Optovue) and evaluate the relationship between this parameter and retinal nerve fiber (RNFL) thickness parameters. Material and Method: 43 eyes of 43 primary open angle glaucoma and pseudoexfoliation glaucoma patients and 46 eyes of the 46 healthy controls were included in the study. All of the participants underwent routine ophthalmological examination, intraocular pressure measure- ments by Goldman applanation tonometry and RNFL / GCC thickness measurements. Results: The mean age of the participants was 63.2±11.6 years (41-83 years) in the glau- coma group and 62.5±9.9 years (45-83 years) in the control group (p>0.05). The mean GCCs in the superior and inferior quadrants in the glaucoma group were 78.1±12.5μm (49.3-98.1 μm) and 74.3±13.8μm (50.0-99.14 μm, whereas they were measured as 98.1±9.9 μm (72.08- 114.0μm) and 100.2±10.7 μm (76.1-124,1 μm) in the control group, respectively (p=0.001 and p=0.001). When RNFL thicknesses were compared between glaucoma and control groups, the differences in each quadrant were found to be statistically significant. In the glaucoma group, there were significant correlations between the inferior/superior GCCs and RNFL thicknesses except NL1, NL2,NU1,SN1 quadrants for the former and NL1 quadrant for the latter, respectively. Conclusion: As a new generation optical coherence tomography, using RTVue 100 is ad- vantageous by means of its ability to measure GCC in addition to RNFL thickness in glauco- matous patients.

Özet

Amaç: RTVue 100 (Optovue) ile glokomatöz ve non-glokomatöz bireylerde ölçülen gangli- yon hücre kompleksinin (GHK) karşılaştırılması ve bu parametrenin diğer retina sinir lifi ta- bakası (RSLT) kalınlığı parametreleri ile ilişkisinin değerlendirilmesi. Gereç ve Yöntem: Çalışmaya 43 primer açık açılı ve psödoeksfolyatif glokomlu olgunun 43 gözü ve 46 sağlıklı olgunun 46 gözü dahil edildi. Bu kapsamda tüm olgularda rutin oftal- molojik muayene, Goldman aplanasyon tonometresi ile göz içi basıncı ölçümü ve RTVue 100 (Optovue) ile RSLT kalınlığı/ GHK ölçümleri yapıldı. Bulgular: Olguların ortalama yaşı glokom grubunda 63,2±11,6 yıl (41-83), kontrol gru- bunda 62,5±9,9 yıldı (45-83 yıl) (p>0,05). Superior ve inferior kadranda ortalama GHK glo- kom grubunda 78,1±12,5μm (49.3-98.1 μm) ve 74,3±13,8μm (50,0-99,14 μm), kontrol gru- bunda ise sırasıyla 98,1±9.9 μm (72,08-114.0μm) ve 100.2±10,7 μm (76,1-124,1 μm) olarak saptandı (p=0,001 ve p=0,001). RSLT kalınlığı tüm kadranlarda kontrol ve glokom grupları arasında karşılaştırıldığında her iki grupta istatistiksel olarak anlamlı derecede farklı bulun- du. Glokom grubunda, inferior/superior GHK ile RSLT kalınlığı değerleri arasındaki korelas- yonlar, sırası ile NL1, NL2, NU1, SN1 kadranları ve NL1 kadranı dışında anlamlıydı. Sonuç: Glokomatöz olgularda yeni jenerasyon bir optik koherans tomografi olan RTVue 100’ün kullanılması, RSLT kalınlığı değerlendirilmesine ek olarak, GHK ölçümünün yapıla- bilmesi açısından avantajlıdır.

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Cite This Article

AKTAŞ, Z., YAYLACIOĞLU, F., AVŞİN, F. Ö., HASANREİSOĞLU, C. M., BÖLÜK, S. O., KAVAKLI, S. (2014). Comparison of retinal nerve fiber layer thicknesses measured with rtvue 100 in glaucomatous and nonglaucomatous cases. MN Oftalmoloji, Cilt: 21 - Sayı: 3, 179–184. https://ajindex.com/articles/295623

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