AI Summary & Key Takeaways
AI InsightConclusion: No significant differences were found between patients with obstructive sleep apnea syndrome and healthy individuals regarding the anterior segment topographic parameters and also no significant differences in the relation with the disease severity.
📌 3 Key Takeaways
Abstract
Objective: To evaluate the anterior segment parameters by combined Scheimpflug-Placido topography system in patients with obstructive sleep apnea syndrome, and to define their relation with disease severity. Material and Method: In this study, 44 eyes of 44 patients with obstructive sleep apnea syndrome, who had not been treated before, recently diagnosed with polysomnography and 78 eyes of 39 healthy subjects were compared. Additionally, the obstructive sleep apnea syndrome group was divided into two subgroups based on the AHI values as follows: 22 patients with mild/moderate (4-<=30) and 22 patients with severe (>30). Sirius topography system was used to evaluate horizontal visible iris diameter, central corneal thickness, anterior chamber depth, anterior chamber volume, iridocorneal angel, corneal volume, horizontal anterior chamber diameter and simulated keratometry readings (Sim K1, Sim K2) parameters. Results: Statistically significant differences in topographic parameters was not found between obstructive sleep apnea syndrome patients and normal population ( Student's t-test, p >0.05). Central corneal thickness and corneal volume were 527.44±37.28 µm and 56.61±4.15 mm3 in patients with obstructive sleep apnea syndrome, and 537.83±29.37 µm and 57,20 ± 3.45 mm3 in the controls, respectively (p=0.05 and p=0.33). Anterior chamber depth and anterior chamber volume were 2.76±0.44 mm and 143.60±37.30 mm3 in the obstructive sleep apnea syndrome group, and 2.86±0.44 mm and 146.68 ± 41.49 mm3 in the control group, respectively (p=0.23 and p=0.74). In addition, there was no difference in topographic parameters between the obstructive sleep apnea syndrome groups (p>0.05). Conclusion: No significant differences were found between patients with obstructive sleep apnea syndrome and healthy individuals regarding the anterior segment topographic parameters and also no significant differences in the relation with the disease severity.
Özet
Amaç: Obstrüktif uyku apne sendromlu hastalarda ön segment parametrelerini kombine Scheimpflug-Placido topografi sistemi ile değerlendirmek ve hastalığın şiddeti ile ilişkisini belirlemek.Gereç ve Yöntem: Bu çalışmada polisomnografi ile teşhis edilen ve daha önce tedavi edilmemiş 44 obstrüktif uyku apne sendromlu olgunun 88 gözü ile 40 normal olgunun 80 gözü karşılaştırıldı. Ayrıca, obstrüktif uyku apne sendromlu grubu AHI değerlerine göre hafif/orta (4 30) obstrüktif uyku apne sendromlu olan 22 hasta olmak üzere iki alt grubaayrıldı. Sirius topografi sistemi horizontal görünür iris çapı, merkezi kornea kalınlığı, ön kamara derinliği, ön kamara hacmi, iridokorneal açı,kornea hacmi, horizontal ön kamara çapı ve simulasyon keratometri (sim K1, sim K2) parametreleri değerlendirme için kullanıldı. Bulgular: Obstrüktif uyku apne sendromlu hastalar ile normal popülasyon ön segment topografik parametreleri arasında istatistiksel anlamlı fark bulunamadı (p>0,05). Merkezi kornea kalınlığı ve kornea hacmi obstrüktif uyku apne sendromlu hastalarda sırasıyla 527,44±37,28µm ve 56,61±4,15 mm3, kontrollerde aynı sırayla 537,83±29,37 µm ve 57,20±3,45 mm3idi (p=0,05 ve p=0,33). Ön kamara derinliği ve ön kamara hacmi, obstrüktif uyku apne sendromlu grubunda sırasıyla 2,76±0,44 mm ve 143,60±37,30 mm3, kontrol grubunda aynı sırayla 2,86 ±0,44 mm ve 146,68 ± 41,49 mm3olarak bulundu (p=0,23 ve p=0,74). Ayrıca, OUAS grupları arasındaki topografik parametrelerde istatistiksel olarak anlamlı fark yoktu (p >0,05). Sonuç: Obstrüktif uyku apne sendromlu hastalarla sağlıklı bireyler arasında, ön segment topografik parametreler ve hastalığın şiddeti ileilişkisi açısından istatistiksel olarak anlamlı fark bulunamamıştır.