Journals / MN Oftalmoloji / 2016 / Cilt: 23 - Sayı: 3

Corneal Hysteresis and Corneal Resistance Factor in Primer Open Angle Glaucoma, Normal Tension Glaucoma and Ocular Hypertension

Primer Açık Açılı Glokom, Normotansif Glokom ve Oküler Hipertansiyonda Korneal Histerezis ve Korneal Direnç Faktörü

Pages
151–155
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It seems to be an useful parameter for early diagnosis of glaucoma.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To compare corneal hysteresis and corneal resistance factor obtained with the ocular response analyzer in primary open angle glaucoma, normal tension glaucoma, ocular hypertension and normal subjects.
📊
Key Findings & Data:Material and Method: One hundred twenty seven eyes of 66 cases with primary open angle glaucoma, 48 eyes of 24 cases with normal tension glaucoma, 110 eyes of 60 cases with ocular hypertension and 172 eyes of 89 control subjects were enrolled in the study.
💡
Conclusion & Impact:It seems to be an useful parameter for early diagnosis of glaucoma.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To compare corneal hysteresis and corneal resistance factor obtained with the ocular response analyzer in primary open angle glaucoma, normal tension glaucoma, ocular hypertension and normal subjects. Material and Method: One hundred twenty seven eyes of 66 cases with primary open angle glaucoma, 48 eyes of 24 cases with normal tension glaucoma, 110 eyes of 60 cases with ocular hypertension and 172 eyes of 89 control subjects were enrolled in the study. Intraocular pressure was measured with Goldmann applanation tonometry, corneal hysteresis and corneal resistance factor were measured with ocular response analyzer, central corneal thickness was measured with ultrasonic pachymetry. The values of corneal hysteresis and KDF were compared between groups and the relation with central corneal thickness was assessed. Results: In primary open angle glaucoma, normal tension glaucoma, ocular hypertension and control subjects corneal hysteresis was 9.31±1.79 mmHg, 9.23±1.65 mmHg, 9.94±1.84 mmHg, 10.58±1.71 mmHg; corneal resistance factor was 10.36±1.73 mmHg, 9.02±1.67 mmHg, 12.08±1.77 mmHg, 10.53±1.74 mmHg; central corneal thickness was 551.10±37.59 ?m, 517.27±38.50 ?m, 578.53±41.30 ?m, 548.52±30.94 ?m, respectively. corneal hysteresis was lower in primary open angle glaucoma and normal tension glaucoma groups when compared to ocular hypertension and control groups (p<0.05). In all study groups, corneal hysteresis and corneal resistance factor were positively correlated with central corneal thickness (r=0.42, 0.62, respectively), but correlation was less with corneal hysteresis when compared to corneal resistance factor. Conclusion: Corneal hysteresis was found lower in glaucomatous eyes when compared to non-glaucomateus eyes. It seems to be an useful parameter for early diagnosis of glaucoma.

Özet

Amaç: Primer açık açılı glokom, normotansif glokom, oküler hipertansiyon ve normal olgularda oküler respons analizörü ile ölçülen korneal histerezis ve korneal direnç faktörünü karşılaştırmayı amaçladık. Gereç ve Yöntem: Primer açık açılı glokomlu 66 olgunun 127 gözü, oküler hipertansiyonlu 60 olgunun 110 gözü, normotansif glokomlu 24olgunun 48 gözü ve kontrol grubunda 89 olgunun 172 gözü çalışmaya alındı. Goldmann aplanasyon tonometrisi ile göz içi basıncı, oküler respons analizörü ile korneal histerezis ve korneal direnç faktörü değerleri, ultrasonik pakimetri ile merkezi kornea kalınlığı ölçümü yapıldı.Gruplar arası korneal histerezis ve korneal direnç faktörünü değerleri karşılaştırıldı ve merkezi kornea kalınlığı ile olan ilişkileri incelendi. Bulgular: Primer açık açılı glokom, normotansif glokom, oküler hipertansiyon ve normal grupta sırasıyla korneal histerezis 9,31±1,79mmHg, 9,23±1,65 mmHg, 9,94±1,84 mmHg ve 10,58±1,71 mmHg, korneal direnç faktörünü 10,36±1,73 mmHg, 9,02±1,67 mmHg, 12,08±1,77mmHg ve 10,53±1,74 mmHg, merkezi kornea kalınlığı 551,10±37,59 ?m, 517,27±38,50 ?m, 578,53±41,30 ?m ve 548,52±30,94 ?m bulundu.Korneal histerezis, primer açık açılı glokom ve normotansif glokom grubunda, kontrol ve oküler hipertansiyon grubuna göre daha düşük saptandı (p <0,05). Tüm çalışma grubunda, korneal histerezis ve korneal direnç faktörünün merkezi kornea kalınlığı ile pozitif yönde korele olduğu görüldü (sırasıyla; r=0,42, 0,62). Korneal histerezisteki korelasyon korneal direnç faktörüne göre daha düşük bulundu. Sonuç: Korneal histerezis, glokomlu gözlerde nonglokomatöz gözlere göre daha düşük bulunmuştur. Glokomun erken tanısında yararlı birparametre olarak gözükmektedir.

🔖

Cite This Article

ASLANKARA, H., ARIKAN, G., ÇETİN, G., GÜNENÇ, Ü. (2016). Corneal Hysteresis and Corneal Resistance Factor in Primer Open Angle Glaucoma, Normal Tension Glaucoma and Ocular Hypertension. MN Oftalmoloji, Cilt: 23 - Sayı: 3, 151–155. https://ajindex.com/articles/295581

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Weinreb RN, Khaw PT. Primary open-angle glaucoma. Lancet 2004;363:1711-20.
  2. Ehler N, Hjortdal J. Corneal thickness:measurement and implica- tions.Exp Eye Res 2004;78:543-8.
  3. Goldmann H, Schmidt T. Über Applanationstonometrie. Ophthalmologica 1957;134;221-42.
  4. Ehlers N, Bramsen T, Sperling S. Applanation tonometry and cen- tral corneal thickness. Acta Ophthalmol 1975;53:34-43. Gordon. Beser JA. Brandt JD. Hever DK. Higginbotham EJ. et al. The Ocular Hypertension Treatment Study. Baseline factors that predict the onset of primary open angle glaucoma. Arch Ophthalmol 2002;120:714-20.
  5. Whitacre MM, Stein R. Sources of error with use of Goldmann- type tonometers. Surv Ophthalmol 1993;38:1-30.
  6. Doughty MJ, Zaman ML. Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis ap- proach. Surv Ophthalmol 2000;44:367-408
  7. Liu J, Roberts CJ. Influence of corneal biomechanical properties on intraocular pressure measurement: quantitative analysis. J Cataract Refract Surg 2005;31:146-55.
  8. Broman AT, Congdon NG, Bandeen-Roche K, Quigley HA. Influence of corneal structure, corneal responsiveness, and other ocular parameters on tonometric measurement of intraocular pres- sure. J Glaucoma 2007;16:581-8. Luce DA. Determining the in vivo biomechanical properties of the cornea with an ocular response analyzer. J Cataract Refract Surg 2005;31:156-62. Kotecha A.What biomechanical properties of the cornea are rele- vant for the clinician? Surv Ophthalmol 2007;52:109-14.
  9. Kotecha A, Elsheikh A, Roberts CR, Zhu H, Garway-Heath D. Corneal thickness- and age-related biomechanical properties of the cornea measured with the ocular response analyzer. Invest Ophthalmol Vis Sci 2006;47:5337-47.
  10. Laiquzzaman M, Bhojwani R, Cunliffe I, Shah S. Diurnal varia- tion of ocular hysteresis in normal subjects: relevance in clinical context. Clin Experiment Ophthalmol 2006;34:114-8.
  11. Shah S, Laiquzzaman M, Cunliffe I, Mantry S. The use of the Reichert ocular response analyser to establish the relationship be- tween ocular hysteresis, corneal resistance factor and central corneal thickness in normal eyes. Cont Lens Anterior Eye 2006; 29:257-62.
  12. Lam A, Chen D, Chiu R, Chiu WS. Comparison of IOP measure- ments between ORA and GAT in normal Chinese. Optom Vis Sci 2007;84:909-14.
  13. Martinez-de-la-Casa JM, Garcia-Feijoo J, Fernandez-Vidal A, Mendez-Hernandez C, Garcia-Sanchez J. Ocular response ana- lyzer versus Goldmann applanation tonometry for intraocular pres- sure measur