Journals / MN Oftalmoloji / 2018 / Cilt: 25 - Sayı: 4

Evaluation of Anterior and Posterior Segment Ocular Changes in the Second and Third Trimesters of Pregnancy

Gebelerde İkinci ve Üçüncü Trimesterde Gözün Ön ve Arka Bölüm Değişikliklerinin Değerlendirilmesi

Pages
188–192
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We think that during ophthalmologic evaluation in pregnancy its important to consider these alterations.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To evaluate the ocular anterior and posterior segment physiopathological changes during the second and third trimester of preg- nancy.
📊
Key Findings & Data:Material and Method: This study consists of, 240 eyes of 120 pregnant women who presented to our hospital for routine pregnancy exami- nation were included.
💡
Conclusion & Impact:We think that during ophthalmologic evaluation in pregnancy its important to consider these alterations.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To evaluate the ocular anterior and posterior segment physiopathological changes during the second and third trimester of preg- nancy. Material and Method: This study consists of, 240 eyes of 120 pregnant women who presented to our hospital for routine pregnancy exami- nation were included. In this prospective study; central corneal thickness, keratometry, intraocular pressure, central macular thickness and reti- nal nerve fiber layer thickness measurements were taken from the healty pregnants both in the second (14-26 weeks) and third trimesters (27- 41 weeks). Right eyes were accepted as group 1 and left eyes were accepted as group 2. The results of second and third trimester were compared statistically. IBM SPSS Statistics 22 program was used for statistical analysis. The p value <0.05 was considered statistically significant. Results: Average keratometry values of group 1 and group 2 in the second trimester were 43.26±1.26 diopters; 43.42±1.28 diopters and group 1 and group 2 in the third trimester were 43.58±1.26; 43.68±1.28 diopters respectively. Average intraocular pressure of group 1 and group 2 in second trimester were 14.24±3.07; 14.23±2.99 mmHg and group 1 and group 2 in third trimester were 13.05±3.21; 12.85±3.0 mmHg re- spectively. Average central corneal thickness values of group 1 and group 2 in second trimester were 551.34±30.68 microns; 553.76±31.67 mi- crons and group 1 and group 2 in third trimester were 556.91±33.40; 558.65±31.74 microns respectively. Average retinal nerve fiber layer val- ues of group 1 and group 2 in second trimester were 108.65±12.37; 108.93±9.62 microns and group 1 and group 2 in third trimester were 105.28±12.31; 105.62±10.82 microns respectively. Average central macular thickness values of group 1 and group 2 in second trimester were 244.29±24.45; 246.60±29.39 microns and group 1 and group 2 in third trimester were 253.85±28.85; 256.63±31.46 microns respectively. When the results of the second and third trimesters were compared, the increase of central corneal thickness, keratometry, central macular thick- ness,intraocular pressure and retinal nerve fiber layer in the third trimester were found statistically significant (p:0.001 / p<0.01). Conclusion: When we compared the values of the second and third trimesters, we found that in the third trimester the values of central corneal thickness, keratometry, central macular thickness increased, intraocular pressure and retinal nerve fiber layer decreased in comparison to second trimester values. We think that during ophthalmologic evaluation in pregnancy its important to consider these alterations.

Özet

Amaç: Gebelerde ikinci ve üçüncü trimesterde meydana gelen ön ve arka segment oküler fizyopatolojik değişikliklerinin değerlendirilmesi. Gereç ve Yöntem: Çalışmaya hastanemiz gebe polikliniğine rutin muayene için başvuran 120 gebenin 240 gözü dahil edildi. Sağlıklı gebe- lerin ikinci (14-26 haftalar) ve üçüncü (27-41 haftalar) trimesterde santral kornea kalınlığı, keratometri, göz içi basıncı, santral maküla kalın- lığı ve retina sinir lifi kalınlığı ölçümleri yapıldı. Sağ gözler grup 1, sol gözler grup 2 olarak kabul edildi. Grup 1 ve grup 2’den 2. ve 3. tri- mesterde elde edilen tüm ölçümler birbirleriyle karşılaştırıldı. İstatistiksel analizler için IBM SPSS Statistics 22 programı kullanıldı. p<0,05 ise aradaki fark istatistiksel olarak anlamlı kabul edildi. Bulgular: K değer ortalaması grup 1 ve grup 2’de 2. trimesterde sırasıyla 43,26±1,26 diyoptri; 43,42±1,28 diyoptri iken; 3. trimesterde 43,58±1,26, 43,68±1,28 diyoptri olarak bulundu. Göz içi basıncı ortalaması grup 1 ve grup 2’de 2. trimesterde sırasıyla 14,24±3,07, 14,23±2,99 mmHg iken, 3. trimesterde 13,05±3,21, 12,85±3,0 mmHg olarak ölçüldü. Santral kornea kalınlığı ortalaması grup 1 ve grup 2’de 2. trimester- de sırasıyla 551,34±30,68 mikron; 553,76±31,67mikron iken; 3. trimesterde 556,91±33,40, 558,65±31,74 mikron olarak bulundu. Retina sinir lifi ortalaması grup 1 ve grup 2’de 2. trimesterde sırasıyla 108,65±12,37; 108,93±9,62;3 mikron; 3.trimesterde 105,28±12,31; 105,62±10,82 mikron olarak bulundu. Santral maküla kalınlığı ortalaması grup 1 ve grup 2’de 2. trimesterde sırasıyla 244,29±24,45; 246,60±29,39 mikron; 3. trimesterde 253,85±28,85, 256,63±31,46 mikron olarak bulundu. Gebelerde 3. trimester 2. trimester ile karşılaştırılınca, 3. trimesterde kera- tometri, santral kornea kalınlığı ve santral maküla kalınlığı değerlerinde görülen artış ile göz içi basıncı ve retina sinir lifi değerlerindeki dü- şüş her iki grupta istatistiksel olarak anlamlı bulundu (p:0,001 / p<0,01). Sonuç: Gebelerde 2. trimester ile 3. trimester karşılaştırılınca 3. trimesterde keratometri, santral kornea kalınlığı, santral maküla kalınlığı değerlerinde artış; göz içi basıncı ve retina sinir lifi değerlerinde düşüş izlenmiştir. Gebelerde oftalmolojik değerlendirme yapılırken bu deği- şimlerin dikkate alınması gerektiğini düşünmekteyiz.

🔖

Cite This Article

KÖKÇEN, H. K., AKKAYA, S., AÇIKALIN, B., ÖZKURT, Y., ARSAN, A., YURTSEVEN, Ö. G. (2018). Evaluation of Anterior and Posterior Segment Ocular Changes in the Second and Third Trimesters of Pregnancy. MN Oftalmoloji, Cilt: 25 - Sayı: 4, 188–192. https://ajindex.com/articles/295527

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Carlin A, Alfirevic Z. Physiological changes of pregnancy and monitoring. Best Pract Res Clin Obstet Gynaecol 2008;22:801-23.
  2. Thornburg KL, Jacobson SL, Giraud GD, Morton MJ. Hemo - dynamic changes in pregnancy. Semin Perinatol 2000;24:11-4.
  3. Chawla S, Chaudhary T, Aggarwal S, Maiti GD, Jaiswal K, Yadav J. Ophthalmic considerations in pregnancy. Med J Armed Forces India 2013;69:278-84. Samra KA. The eye and visual system in pregnancy, what to ex- pect? An in-depth review. Oman J Ophthalmol 2013;6:87-91.
  4. Jadotte YT, Schwartz RA. Melasma: insights and perspectives. Acta Dermatovenerol Croat 2010;18:124-9. Sanke RF. Blepharoptosis as a complication of pregnancy. Ann Ophthalmol 1984;16:720-2.
  5. Schlehter JE, Pidgeon M, Chang D, Fong YC, Trousdale MD, Chang N. Potential role of disrupted lacrimal acinar cells in dry eye during pregnancy. Adv Exp Med Biol 2002;506(Pt A):153-7.
  6. Riss B, Riss P. Corneal sensitivity in pregnancy. Ophthalmologica 1981;183:57-62.
  7. Weinreb RN, Lu A, Beeson C. Maternal corneal thickness during pregnancy. Am J Ophthalmol 1988;105:258-60.
  8. Green K, Phillips CI, Cheeks L, Slagle T. Aqueous humor flow rate and intraocular pressure during and after pregnancy. Ophthal Res 1988;20:353-7.
  9. Efe YK, Ugurbas SC, Alpay A, Ugurbas SH. The course of corneal and intraocular pressure changes during pregnancy. Can J Ophthalmol 2012;47:150-4.
  10. Sharma B, Rekha W, Sharma T, Downey G. Refractive issues in pregnancy. Aust NZ J Obstet Gynaecol 2006;46:186-8.
  11. Spoerl E, Zubaty V, Raiskup-Wolf F, Pillunat LE. Estrogen-in- duced changes in biomechanics in the cornea as a possible reason for keratectasia. Br J Ophthalmol 2007;91:1547-50.
  12. Toda J, Kato S, Sanaka M, Kitano S. The effect of pregnancy on the progression of diabetic retinopathy. Jpn J Ophthalmol 2016; 60:454-8.
  13. Park YJ, Park KH, Woo SJ. Clinical features of pregnancy-asso- ciated retinal and choroidal diseases causing acute visual distur- bance. Korean J Ophthalmol 2017;31:320-7.
  14. Ziai N, Ory SJ, Khan AR, Brubaker RF. Beta-human chorionic gonadotropin, progesterone, and aqueous dynamics during preg- nancy. Arch Ophthalmol 1994;112:801-6.
  15. Suzuki T, Sullivan DA. Estrogen stimulation of proinflammatory cytokine and matrix metalloproteinase gene expression in human corneal epithelial cells. Cornea 2005;24:1004-9.
  16. Kiely PM, Carney LG, Smith G. Menstrual cycle variations of corneal topography and thickness. Am J Optom Physiol Opt 1983;60:822-9.
  17. Park SB, Lindahl KJ, Temnycky GO, Aquavella JV. The effect of pregnancy o