Journals / MN Oftalmoloji / 2019 / Cilt: 26 - Sayı: 4

Comparison of Retinal Vascular Structure With Optical Coherence Tomography Angiography in Children with and Without Occlusion Treatment

Kapama Tedavisi Alan ve Almayan Ambliyop Çocuklarda Retina Vasküler Yapısının Optik Koherans Tomografi Anjiyografi ile Karşılaştırılması

Pages
207–213
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusions: There is no significant difference between the eyes of amblyopic children with and without occlusion treatment in retinal vascular structure.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study is to evaluate the superficial and deep vascular plexus and foveal avascular area of the retina by optical coherence tomography angiography of amblyopic children who had treated with or without occlusion treatment.
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Key Findings & Data:Material and Method: Twenty anisometropic amblyopic eyes who received occlusion treatment (Group 1), 25 anisometropic amblyopic eyes who had no occlusion treatment (Group 2), and 45 healty non ambliopic eyes (control group; Group 3) were included in this crosssectional case- controlled study.
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Conclusion & Impact:Conclusions: There is no significant difference between the eyes of amblyopic children with and without occlusion treatment in retinal vascular structure.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study is to evaluate the superficial and deep vascular plexus and foveal avascular area of the retina by optical coherence tomography angiography of amblyopic children who had treated with or without occlusion treatment. Material and Method: Twenty anisometropic amblyopic eyes who received occlusion treatment (Group 1), 25 anisometropic amblyopic eyes who had no occlusion treatment (Group 2), and 45 healty non ambliopic eyes (control group; Group 3) were included in this crosssectional case- controlled study. Superficial vascular plexus, deep vascular plexus, and foveal avascular area were compared in Group 1, 2, and 3 by optical coherence tomography angiography in a 3x3 mm area in all eyes. Results: The mean age of the patients in Group 1, 2 and 3 were 6.1 ± 1.02, 5.9 ± 0.92 and 6.0 ± 0.93, respectively (p >0.05, for all). Superficial vascular plexus vascular density was measured as 20.45 ± 3.73, 21.39±3.91, 20.24 ± 3.61, while deep vascular plexus vascular density was measured as 18.39 ± 3.05, 19.85 ± 4.38, 19.62 ± 5.53 in foveal area, in Groups 1, 2 and 3, respectively. Superficial vascular plexus vascular density was measured as 49.01 ± 4.84, 48.45 ± 3.01, 48.88 ± 3.76, while deep vascular plexus vascular density was measured as 52.54 ± 4.27, 49.45 ± 3.59, 52.01 ± 3.37 in parafoveal area, in Group 1, 2 and 3 respectively. No significant difference was measured in superficial vascular plexus and deep vascular plexus layer at foveal and parafoveal area in all groups. No significant difference was found between the groups in the foveal and parafoveal region in terms of foveal avascular area. Conclusions: There is no significant difference between the eyes of amblyopic children with and without occlusion treatment in retinal vascular structure.

Özet

Amaç: Kapama tedavisi alan ambliyop çocuklar ile kapama tedavisi almayan ambliyop çocuklarda retina yüzeyel kapiller pleksus ve derin kapiller pleksus yapısını optik koherans tomografi anjiyografi ile değerlendirmek. Gereç ve Yöntem: Kesitsel vaka kontrollü yapılan bu çalışmada kapama tedavisi alan 20 anizometropik ambliyop hastanın 20 ambliyop gözü (Grup 1) ve anizometropik ambliyopisi bulunan ancak hiç kapama tedavisi yapılmamış 25 hastanın 25 ambliyop gözü (Grup 2) ve sağlıklı 45 hastanın 45 gözü (kontrol grubu; Grup 3) çalışmaya dahil edildi. Tüm gözlerde 3x3 mm alan haritasında optik koherans tomografi anjiyografi ile ölçülen retinanın yüzeyel ve derin vasküler yapı dansitesi ve foveal avasküler alan karşılaştırıldı. Bulgular: Grup 1, 2 ve 3’teki hastaların yaşları sıra ile 6,1 ± 1,02, 5,9 ± 0,92 ve 6,0 ± 0,93 idi (p >0,05). Foveal alanda yüzeyel kapiller pleksus vasküler dansitesi Grup 1, 2 ve 3’te sırası ile 20,45 ± 3,73, 21,39 ± 3,91, 20,24 ± 3,61 olarak ölçülürken, derin kapiller pleksus vasküler dansitesi 18,39 ± 3,05, 19,85± 4,38, 19,62 ± 5,53 olarak ölçüldü. Parafoveal alanda yüzeyel kapiller pleksus vasküler dansitesi Grup 1, 2 ve 3’te sırası ile 49,01 ± 4,84, 48,45 ± 3,01, 48,88 ± 3,76 olarak ölçülürken, derin kapiller pleksus vasküler dansitesi 52,54 ± 4,27, 49,45 ± 3,59, 52,01 ± 3,37 olarak ölçüldü. Foveal ve parafoveal alanda ne yüzeyel kapiller pleksus ne de derin kapiller pleksus tabakasında vasküler dansite açısından anlamlı fark görülmedi. Foveal ve parafoveal alanda yapılan foveal avasküler alan ölçümlerinde gruplar arasında anlamlı fark görülmedi. Sonuç: Retina vasküler yapısı, kapama tedavisi alan ambliyop gözler ile kapama tedavisi almayan ambliyop gözler arasında belirgin bir farklılık göstermemektedir

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Cite This Article

ÇINAR, E., YÜCE, B., ASLAN, F., ERBAKAN, G., KÜÇÜKERDÖNMEZ, F. C. (2019). Comparison of Retinal Vascular Structure With Optical Coherence Tomography Angiography in Children with and Without Occlusion Treatment. MN Oftalmoloji, Cilt: 26 - Sayı: 4, 207–213. https://ajindex.com/articles/295382

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References (13)

  1. Repka M. Amblyopia: basics, questions, and practical management. In: Lyons C, Lambert S, eds. Taylor and Hoyt’s Pediatric Ophthalmology and Strabismus. 5th ed. Amsterdam, Netherlands: Elsevier; 2017:754-61
  2. Aygit ED, Yilmaz I, Ozkaya A, Alkin Z, Gokyigit B, Yazici AT, Demirok A. Choroidal thickness of children’s eyes with anisometropic and strabismic amblyopia. J AAPOS 2015;19(3):237- 241
  3. Li J, Ji P, Yu M. Meta-analysis of retinal changes in unilateral amblyopia using optical coherence tomography. Eur J Ophthalmol.2015(5);25:400-9
  4. Hussain N, Hussain A. Diametric measurement of foveal avascular zone in healthy young adults using optical coherence tomography angiography. Int J Ret Vitr. 2016;2:27
  5. Yilmaz I, Ocak OB, Yilmaz BS, Inal A, Gokyigit B, Taskapili M. Comparison of quantitative measurement of foveal avascular zone and macular vessel density in eyes of children with amblyopia and healthy controls: an optical coherence tomography angiography study. J AAPOS. 2017;21(3):224-8
  6. Lonngi M, Velez FG, Tsui I, Davila JP, Rahimi M, Chan C, Sarraf D, Demer JL, Pineles SL. Spectral-Domain Optical Coherence Tomographic Angiography in Children With Amblyopia. JAMA Ophthalmol. 2017;135(10):1086-91
  7. Demirayak B, Vural A, Onur IU, Kaya FS, Yigit FU. Analysis of Macular Vessel Density and Foveal Avascular Zone Using Spectral-Domain Optical Coherence Tomography Angiography in Children With Amblyopia. J Pediatr Ophthalmol Strabis. 2019;56(1):55-9
  8. Chen W, Lou J, Thorn F, et al. Retinal Microvasculature in Amblyopic Children and the Quantitative Relationship Between Retinal Perfusion and Thickness. Invest Ophthalmol Vis Sci. 2019;60(4):1185-91
  9. Pujari A, Chawla R, Mukhija R, et al. Assessment of macular vascular plexus density using optical coherence tomography angiography in cases of strabismic amblyopia. Indian J Ophthalmol. 2019;67(4):520-1
  10. American Academy of Ophthalmology Pediatric Ophthalmology/ Strabismus Panel. Preferred Practice Pattern Guidelines Amblyo - pia. San Franciso, CA: American Academy of Ophthal mo logy; 2012
  11. Von Noorden GK, Dowling JE, Ferguson DC. Experimental amblyopia in monkeys. I. Behavioral studies of stimulus deprivation amblyopia. Arch Ophthalmol. 1970;84(2):206-14
  12. Guo L, Tao J, Xia F, Yang Z, Ma X, Hua R. In vivo optical imaging of amblyopia: Digital subtraction autofluorescence and splitspectrum amplitude-decorrelation angiography. Lasers Surg Med. 2016;48(7):660-7
  13. Sobral I, Rodrigues TM, Soa