Journals / MN Oftalmoloji / 2020 / Cilt: 27 - Sayı: 3

Light and Electron Microscopic Evaluation of Unilateral Conjunctivochalasis in a Young Patient

Genç Hastada Tek Taraflı Konjonktivoşalazisin Işık ve Elektron Mikroskobik Olarak Değerlendirilmesi

Pages
178–181
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In our case, the pathological changes observed in the conjunctival tissue suggest that inflammatory and mechanical effects may play a role in the development of conjunctivochalasis.

📌 3 Key Takeaways

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Objective & Hypothesis:In this case report, we aimed to evaluate the histopathological features of the youngest unilateral conjunctivochalasis case reported in the literature and to present our treatment approach.
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Key Findings & Data:Light microscopic examination of the conjunctiva revealed increased inflammatory cell, lymphatic ectasia, goblet cell loss, and elastic fiber destruction.
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Conclusion & Impact:In our case, the pathological changes observed in the conjunctival tissue suggest that inflammatory and mechanical effects may play a role in the development of conjunctivochalasis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this case report, we aimed to evaluate the histopathological features of the youngest unilateral conjunctivochalasis case reported in the literature and to present our treatment approach. A twenty-three year old female patient who did not have any medical history presented with complaints of watery eyes and foreign body sensation in the left eye. In ocular examination conjunctivochalasis was present in the lower and temporal region of the left eye. The patient's symptoms did not regress after lubricant treatment. Loose conjunctival tissue was excised from the patient’s left eye and conjunctival defect was closed with amniotic membrane. Light microscopic examination of the conjunctiva revealed increased inflammatory cell, lymphatic ectasia, goblet cell loss, and elastic fiber destruction. Electron microscopic examination revealed a decrease in intracellular connections between epithelial cells and an increase in distance between cells. All the symptoms and signs disappeared and the tear meniscus completely resolved in the first month postoperatively. In our case, the pathological changes observed in the conjunctival tissue suggest that inflammatory and mechanical effects may play a role in the development of conjunctivochalasis.

Özet

Literatürde bildirilen en genç tek taraflı konjonktivoşalazis olgusunda saptanan histopatolojik özellikleri değerlendirmek ve tedavi yaklaşımını sunmayı amaçladığımız bu olgu sunumunda, tıbbi öyküsünde bir özellik bulunmayan ve sol gözde sulanma, yabancı cisim hissi şikayetleri olan 23 yaşında kadın hasta kliniğimize başvurdu. Muayenesinde sol göz alt ve temporal bölgede konjonktivoşalazis mevcuttu. Lubrikan tedavi sonrası şikayetlerinde azalma olmayan hastanın sol gözünden gevşek konjonktival doku eksize edildi ve konjonktival açıklık amniyon zar ile kapatıldı. Konjonktivanın ışık mikroskobisi ile incelemesinde enflamatuvar hücre artışı, lenfatik ektazi, Goblet hücre kaybı, elastik lif harabiyeti saptanırken, elekt ron mikroskobisi incelemesi de epitel hücreler arası bağlantılardaki azalma ve hücreler arası mesafede artış ortaya koydu. Cerrahi sonrası birinci ayda tüm semptom ve bulguların ortadan kalktığı, gözyaşı menisküsünün düzeldiği görüldü. Olgunun konjonktival doku örneğinde saptanan patolojik değişiklikler konjonktivoşalazis gelişiminde genç hastalarda da enflamatuvar ve mekanik etkilerin birlikte rol alabileceğini düşündürmüştür

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Cite This Article

HARBİYELİ, İ. İ., ERDEM, E., IŞIK, P., ERDOĞAN, Ş., KUYUCU, Y., POLAT, S., YAĞMUR, M. (2020). Light and Electron Microscopic Evaluation of Unilateral Conjunctivochalasis in a Young Patient. MN Oftalmoloji, Cilt: 27 - Sayı: 3, 178–181. https://ajindex.com/articles/295328

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References (10)

  1. Watanabe A. Yokoi N. Kinoshita S. Hino Y. Tsuchihashi Y. Cli - nico pathologic study of conjunctivochalasis. Cornea. 2004;23(3); 294-8
  2. Fernández-Hortelano A. Moreno-Montañés J. Heras-Mulero H. Sadaba-Echarri LM. Amniotic Membrane Transplantation With Fibrin Glue As Treatment of Refractory Conjunctivochalasis. Arch Soc Esp Oftalmol. 2007;82(9):571-4
  3. Di Pascuale MA. Espana EM. Kawakita T. Tseng SCG. Clinical characteristics of conjunctivochalasis with or without aqueous tear deficiency. Br J Ophthalmol. 2004;88(3):388-92
  4. Mimura T. Yamagami S. Usui T. et al. Changes of conjunctivochalasis with age in a hospital-based study. Am J Ophthalmol. 2009;147(1):171-7
  5. Ward SK. Wakamatsu TH. Dogru M. et al. The role of oxidative stress and inflammation in conjunctivochalasis. Invest Ophthal - mol Vis Sci. 2010;51(4):1994-2002
  6. Harbiyeli II. Erdem E. Erdogan S. Kuyucu Y. Polat S. Yagmur M. Investigation of conjunctivochalasis histopathology with light and electron microscopy in patients with conjunctivochalasis in different locations. International ophthalmology. 2019;39:1491-9
  7. Francis IC. Chan DG. Kim P. et al. Case-controlled clinical and histopathological study of conjunctivochalasis. Br J Ophthalmol. 2005;89(3):302-5
  8. Acar M. Firat H. Yüceege M. Dogan AS. Çaliskan S. Gürdal C. The Presence of Conjunctivochalasis in Obstructive Sleep Apnea Patients. Eye Contact Lens. 2018;44(1):163-6
  9. Balci O. Clinical characteristics of patients with conjunctivochalasis. Clin Ophthalmol (Auckland, NZ). 2014;8:1655-60
  10. Çağlayan M. Kösekahya P. Gürdal C. Saraç Ö. Comparison of Electrocoagulation and Conventional Medical Drops for Treatment of Conjunctivochalasis: Short-Term Results. Turk J Ophthalmol. 2018;48(2):61-5.