Journals / MN Oftalmoloji / 2013 / Cilt: 20 - Sayı: 2

Evaluation of retinal nerve fiber layer and ganglion cell complex with optical coherence tomography in migraine patients

Migren hastalarında optik koherans tomografi ile retina sinir lifi tabakası ve ganglion hücre kompleksinin değerlendirilmesi

Pages
127–131
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The findings must be confirmed with further stud- ies including more patient numbers.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: To evaluate the retinal nevre fiber layer (RNFL) and ganglion cell complex (GCC) with optical coherence tomography (OCT) in migraine patients.
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Key Findings & Data:Material and Method: Forty six eyes of 46 migraine patients (group 1) and 45 eyes of 45 healthy subjects (group 2) were included in this study.
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Conclusion & Impact:The findings must be confirmed with further stud- ies including more patient numbers.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: To evaluate the retinal nevre fiber layer (RNFL) and ganglion cell complex (GCC) with optical coherence tomography (OCT) in migraine patients. Material and Method: Forty six eyes of 46 migraine patients (group 1) and 45 eyes of 45 healthy subjects (group 2) were included in this study. Peripapillary RNFL and GCC thickness measurements were taken with Fourier Domain (FD)-OCT in both groups. The correlation be- tween the obtained values and the duration of the migraine disease, the frequency and the du- ration of the migraine attack or the presence of the aura was evaluated. Results: The mean peripapillary RNFL thickness was measured in temporal, superior, nasal and inferior quadrants, while the GCC thickness was measured in superior and inferior quadrants, and the values did not show any statistically significant difference between the groups (p>0.05). There were no correlation between the mean thicknesses of RNFL and GCC and and the duration of the migraine disease, the frequency and the duration of the migraine attack or the presence of the aura (p>0.05). Conclusion: In this study, it was demonstrated that migraine disease does not have any ef- fect on the thickness of the RNFL and GCC. The findings must be confirmed with further stud- ies including more patient numbers.

Özet

Amaç: Migren hastalarında retina sinir lifi tabakası (RSLT) ve ganglion hücre kompleksi- nin (GHK) optik koherans tomografi (OKT) ile değerlendirilmesi. Gereç ve Yöntem: Kırkaltı migren hastasının 46 gözü (grup 1) ve 45 sağlıklı bireyin 45 gö- zü (grup 2) çalışmaya dahil edildi. Her iki grupta da Fourier domain (FD)-OKT ile peripa- piller RSLT ve GHK kalınlığı ölçüldü. Migren hastalarında migren süresi, migren atak sıklı- ğı, atak süresi ve aura varlığı ile elde edilen değerler arasında korelasyon olup olmadığına ba- kıldı. Sonuçlar: Ortalama peripapiller RSLT kalınlığı temporal, superior, nazal ve inferior kad- ranlarda, ortalama GHK kalınlığı superior ve inferior kadranlarda ölçüldü ve değerler grup- lar arasında istatistiksel olarak anlamlı bir farklılık göstermedi (p>0,05). Migren hastaların- da ortalama RSLT ve GHK kalınlığı migrenin süresi, migren atağının sıklığı ve süresi veya au- ra varlığı ile korelasyon göstermedi (p>0,05). Tartışma: Bu çalışmada migren hastalığının peripapiller RSLT ve GHK kalınlığı üzerinde etkisi olmadığı gözlenmiştir. Mevcut bulgular daha fazla hasta sayısı içeren ileri çalışmalarla desteklenmelidir.

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Cite This Article

DERELİ, G. C., SARAÇ, Ö., CAN, M. E., GÜRDAL, C., DÖNMEZ, H. K., DENİZ, O., ÇAĞIL, N. (2013). Evaluation of retinal nerve fiber layer and ganglion cell complex with optical coherence tomography in migraine patients. MN Oftalmoloji, Cilt: 20 - Sayı: 2, 127–131. https://ajindex.com/articles/294272

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