Journals / Okmeydanı Tıp Dergisi / 2012 / Cilt: 28 - Sayı: 1

The incidence of TTV in patients with chronic hepatitis B or C

Kronik hepatit B veya C'li hastalarda TTV (Tork teno virüs) insidansı

Pages
8–13
DOI
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Conclusion: The incidence of TTV in chronic hepatitis B or C is not statistically associated with dental treatment, blood transfusion and response to treatment.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study the incidence of TTV (torque teno virus) was investigated on patients with hepatitis B and C in whom persistent virological response was achieved or not.
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Key Findings & Data:Materials and Methods: A total of 68 patients who were monitored between 1998-2007 with the diagnosis of chronic hepatitis B or C in hepatology policlinic were included into this study.
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Conclusion & Impact:Conclusion: The incidence of TTV in chronic hepatitis B or C is not statistically associated with dental treatment, blood transfusion and response to treatment.
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: In this study the incidence of TTV (torque teno virus) was investigated on patients with hepatitis B and C in whom persistent virological response was achieved or not. Furthermore, the issue of whether or not TTV affects the treatment was assessed. Materials and Methods: A total of 68 patients who were monitored between 1998-2007 with the diagnosis of chronic hepatitis B or C in hepatology policlinic were included into this study. For detection of TTV polymerase chain reaction (PCR) method was used. The patients were evaluated in terms of previous dental treatment, surgical operations, blood transfusion which were possible routes of contamination with TTV. Findings: Whereas in 23.5 % of chronic hepatitis B patients TTV DNA was positive, positivity rate was found as 44.1 % in patients with hepatitis C. There is no statistically significant difference between the groups with regard to persistent virological response to treatment (p<0.05). Conclusion: The incidence of TTV in chronic hepatitis B or C is not statistically associated with dental treatment, blood transfusion and response to treatment.

Özet

Amaç: Bu çalışmada kalıcı virolojik yanıt sağlanan ve sağlanamayan kronik hepatit B ve C hastalarında TTV (Tork Teno Virüs) insidansı araştırılmıştır. Ayrıca TTV’nin tedaviyi olumsuz etkileyip etkilemediği değerlendirilmiştir. Gereç ve Yöntemler: Hepatoloji polikliniğinde 1998-2007 tarihleri arasında kronik hepatit B ve C tanısıyla takip edilen toplam 68 hasta bu çalışmaya katılmıştır. TTV tespiti için polimeraz zincir reaksiyonu (PCR) yöntemi kullanılmıştır. TTV’nin bulaş yolları açısından hastalar diş tedavisi olup olmadığı, geçirilmiş operasyon öyküsü, kan transfüzyonu öyküsü açısından da incelenmiştir. Bulgular: Kronik Hepatit B hastalarının % 23.5’inde TTV DNA pozitif iken, kronik hepatit C hasta grubunda ise % 44.1 pozitiflik oranı saptanmıştır. Her iki grupta da tedaviye kalıcı virolojik yanıt verenler ve vermeyenler arasında anlamlı bir farklılık elde edilememiştir (p<0.05). Sonuç: Kronik hepatit B veya C hastalarında TTV insidansı; diş tedavisi, kan transfüzyon öyküsü ve tedaviye yanıt ile istatistiksel olarak ilişkili değildir.

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Cite This Article

KALYON, S., BAYRAM, Y., KUTOĞLU, K., KALYON, S. T., YENİCE, N. (2012). The incidence of TTV in patients with chronic hepatitis B or C. Okmeydanı Tıp Dergisi, Cilt: 28 - Sayı: 1, 8–13. https://ajindex.com/articles/291855

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