Journals / Okmeydanı Tıp Dergisi / 2015 / Cilt: 31 - Sayı: 4

Association Between Uric Acid Levels and Complications and Risk Factors in Patients with Acute Coronary Syndrome

Akut Koroner Sendromlu Hastalarda Ürik Asit Düzeyi ile Risk Faktörlerinin ve Komplikasyonların İlişkisi

Pages
179–183
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We think that this result may be associated with the drugs which were used for heart failure or renal perfusion disorder.

📌 3 Key Takeaways

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Objective & Hypothesis:Material and Method: The charts of the patients diagnosed with Acute Coronary Syndrome in Coronary Intensive Care Unit and Internal Medicine Department of Okmeydani Training and Research Hospital between October 2012 and February 2013 were retrospectively reviewed.
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Key Findings & Data:A total of 117 cases were included in the study. 35 cases which are similar to the patient group in terms of age, sex, and chronic diseases were also included as control group.
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Conclusion & Impact:We think that this result may be associated with the drugs which were used for heart failure or renal perfusion disorder.
🔬Design:Review & Systematic Survey
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Material and Method: The charts of the patients diagnosed with Acute Coronary Syndrome in Coronary Intensive Care Unit and Internal Medicine Department of Okmeydani Training and Research Hospital between October 2012 and February 2013 were retrospectively reviewed. A total of 117 cases were included in the study. 35 cases which are similar to the patient group in terms of age, sex, and chronic diseases were also included as control group. They were compared in terms of age, sex, biochemical parameters, comorbidities, complications, and blood uric acid levels. Results: Average uric acid value of patient group was 6.10±1.80 mg/dL. Uric acid levels were high in 33% of cases. Average uric acid levels in control group patients was 6.47±2.16 mg/dl and were high at 45% in the control group. The difference in elevations in uric acid levels were not statistically significant between the two groups. However, acute coronary syndrome in patients with previous heart failure resulted in high uric acid levels and this was found statistically significant. Discussion: We think that there was no direct association between uric acid levels and acute coronary syndrome. We found higher uric acid levels in patients with heart failure. We think that this result may be associated with the drugs which were used for heart failure or renal perfusion disorder.

Özet

Amaç: Çalışmamızda akut koroner sendrom için risk faktörü olduğunu düşündüğümüz kan ürik asit düzeyinin bu hastalık üzerine etkilerinin araştırılması amaçlanmıştır. Gereç ve Yöntem: Aralık 2012-Şubat 2013 tarihleri arasında, Okmeydanı Eğitim ve Araştırma Hastanesi Koroner Yoğun Bakım Ünitesinde ve Dahiliye kliniklerinde, akut koroner sendrom tanısıyla yatmış hastaların dosyaları retrospektif olarak incelendi. Toplam 117 olgu ile yaş, cinsiyet ve kronik hastalıklar bakımından hasta grubuyla benzer nitelikte olan 35 kişi kontrol grubu olarak çalışmaya alındı. Alt gruplara da ayrılan olgu ve kontrol grubunun; yaşları, cinsiyetleri, biyokimyasal parametreleri, ek hastalıkları, komplikasyonları ve ürik asit düzeyleri karşılaştırıldı. Bulgular: Olgularda ortalama ürik asit düzeyi 6,10±1,80 mg/dl olarak saptandı. Ürik asit düzeyi tüm olguların %33,3'ünde yüksek bulundu. Kontrol grubu hastalarının ortalama ürik asit düzeyi 6,47±2,16 mg/dl saptandı ve hastaların %45,7'sinde yüksek bulundu. Ürik asit yüksekliğinin gruplar arası karşılaştırılmasında istatistiksel olarak anlamlı fark saptanmadı. Ancak kalp yetersizliği olan hastalarda akut koroner sendrom sonrası ürik asit yüksekliği saptandı ve istatiksel olarak anlamlı bulundu

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Cite This Article

AVCI, G. U., HELVACI, A., AVCI, Y., CANBOLAT, İ. P., DURSUN, M. (2015). Association Between Uric Acid Levels and Complications and Risk Factors in Patients with Acute Coronary Syndrome. Okmeydanı Tıp Dergisi, Cilt: 31 - Sayı: 4, 179–183. https://ajindex.com/articles/291795

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