Journals / Okmeydanı Tıp Dergisi / 2015 / Cilt: 31 - Sayı: 3

Clinicopathological Features of Splenectomy Specimens: Experience of 16 Years

Splenektomi Materyallerinin Klinikopatolojik Özellikleri: On altı Yıllık Deneyim

Pages
129–133
DOI
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Therefore, it was concluded that collection of data about the clinicopathological features of splenectomy specimens can contribute to the pathological and epidemiological studies to be done in the future.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We report here our results of pathological assessment of 659 splenectomy cases examined between 1996 and 2012.
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Key Findings & Data:The aim of this study is to investigate the morphological features, indications and the clinical features of the splenectomy specimens.Material and Methods: Clinicopathological features of totally 659 splenectomy specimens were retrospectively evaluated, in terms of age, sex, splenectomy indications; largest size, weight and histopathological diagnosis of the material.Results: The mean age was 40.71±17 and the ratio of male to female was 1.18.
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Conclusion & Impact:Therefore, it was concluded that collection of data about the clinicopathological features of splenectomy specimens can contribute to the pathological and epidemiological studies to be done in the future.
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: We report here our results of pathological assessment of 659 splenectomy cases examined between 1996 and 2012. The aim of this study is to investigate the morphological features, indications and the clinical features of the splenectomy specimens.Material and Methods: Clinicopathological features of totally 659 splenectomy specimens were retrospectively evaluated, in terms of age, sex, splenectomy indications; largest size, weight and histopathological diagnosis of the material.Results: The mean age was 40.71±17 and the ratio of male to female was 1.18. Splenectomy indications of the cases were trauma in 262, hemato-lenfoid diseases in 245, operation procedure in 76, infectious diseases in 40, and splenic mass in 36 of them. Histologically, in all of the trauma specimens, hematoma and congestion were seen. 75 of the operation procedure specimens exhibited congestion and 1 of them amyloid. In the infectious specimens, cyst hydatic was seen in 28, splenic abscess in 7, and granuloma in 3 of them. Conclusion: Spleen still lingers as useless and "vestigial" organ in the minds of surgeons and the pathologists despite its very vital immunological defense activities. Due to the increase in the advanced techniques, it is possible to avoid unnecessary surgery. Finally, the ratio of the splenectomy in general surgical pathology is decreasing gradually. Therefore, it was concluded that collection of data about the clinicopathological features of splenectomy specimens can contribute to the pathological and epidemiological studies to be done in the future.

Özet

Amaç: Bu çalışmada, 1996-2012 yılları arasında incelenen 659 splenektomi materyalinin patolojik değerlendirme sonuçlarını sunduk. Bu çalışmanın amacı, splenektomi materyallerinin klinik özelliklerinin, endikasyonlarının ve morfolojik özelliklerinin araştırılmasıdır.Gereç ve Yöntemler: Toplam 659 splenektomi materyaline ait klinikopatolojik özellikler (yaş, cinsiyet, splenektomi endikasyonu, materyalin en büyük boyutu, ağırlığı, histopatolojik tanı) retrospektif olarak değerlendirilmiştir. Bulgular: Yaş ortalaması 40,71±17 yıl olup, erkek/kadın oranı 1,18'dir. Splenektomi endikasyonları; olguların 262'sinde travma, 245'inde hemato-lenfoid hastalıklar, 76'sında operasyonun prosedürü gereği, 40'ında enfeksiyöz hastalıklar, 36'sında dalak kitlesidir. Histolojik incelemede; travma hastalarının tamamında hematom ve konjesyon; operasyon prosedürü materyallerinin 75'inde konjesyon, 1'inde amiloidoz; infeksiyon olgularının 28'inde kist hidatik, splenik apse, 3'ünde granülom izlenmiştir. Sonuç: Çok önemli immunolojik işlevlerine rağmen, dalak hâlen patologlar ve cerrahlar tarafından yararsız ve ihmal edilebilir bir organ olarak düşünülür. Gelişmiş tekniklerin giderek artmasıyla gereksiz cerrahiden kaçmak olasıdır. Sonuçta, splenektomi materyallerinin oranı, genel cerrahi patolojide giderek azalmaktadır. Bu nedenle; splenektomi materyallerinin klinikopatolojik özelliklerine ait verilerin toplanmasının, yapılacak patoloji ve epidemiyoloji çalışmalarına katkıda bulunabileceği sonucuna varılmıştır.

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Cite This Article

ÖZKÖK, G., ARGON, A., CANPOLAT, S., TAŞLI, F., KARAHAN, B., ZENGEL, B., VARDAR, E. (2015). Clinicopathological Features of Splenectomy Specimens: Experience of 16 Years. Okmeydanı Tıp Dergisi, Cilt: 31 - Sayı: 3, 129–133. https://ajindex.com/articles/291760

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References (14)

  1. Kumar V, Abbas A, Fausto N. Robbins and Cotran Pathologic Basis of Disease. 7th edition. Philadelphia: Elsevier Saunders; 2005,702-706
  2. Porembka MR, Doyle MBM, Chapman WC. Disorders of the spleen. In: Greer J, Foerster J, Rodgers GM, Paraskevas F (eds). Wintrobe's Clinical Hematology. Philadelphia: Lippincott Williams&Williams; 2009,1637- 1655
  3. Adelusola KA, Osasan SA, Afolabi OA. Histopathological study and audit of the spleen in Nigerians. African Journal of Health Sciences 2007;14:195-200
  4. Kraus MD1, Fleming MD, Vonderheide RH. The spleen as a diagnostic specimen: a review of 10 years' experience at two tertiary care institutions. Cancer 2001;91:2001-2009. http://dx.doi.org/10.1002/1097-0142(20010601)91: 11_____2001::AID-CNCR1225>3.0.CO;2-3 5. Coad, J.E, Matutes E, Catovsky D. Splenectomy in lymphoproliferative disorders: A report of 70 cases and review of the literature. Leuk Lymphoma 1993;10:245- 264.
  5. Balague C, Targarona EM, Cerdan G, et al. Longterm outcome after laparoscopic splenectomy related to hematological diagnosis. Surg Endosc 2004;18:1283- 1287.
  6. Khalid A, Haque AU, Naseem L. Spectrum of Disease Entities in Splenectomy Specimen. International Journal of Pathology 2006;4(2):88-93
  7. Gertz R, Salim A, Teixeira P, et al. Indications for routine pathologic examination of specimens removed during trauma operations. World J Surg 2010;34:733-7.
  8. Parsons L, Thompson JE. Traumatic rupture of the spleen from nonpenetrating injuries. Ann Surg 1958;147:214-223.
  9. Farhi DC, Ashfaq R. Splenic pathology after traumatic injury. Am J Clin Pathol 1996;105:474-478
  10. Gaum AR, Gaum D. Traumatic rupture of the spleen: report of 11 cases. Can Med Assoc J 1958;78:189-194
  11. Drachenberg CB, Papadimitriou JC. Splenic pathology in different forms of traumatic injury. Am J Clin Pathol 1996;106:695
  12. Barnard H, Dreef EJ, Van Krieken JH. The ruptured spleen. A histological, morphometrical and immunohistochemical study. Histol Histopathol 1990;5:299-304
  13. Al-Kindi H, Devi L, George M. Splenic Pathology in Traumatic Rupture of the Spleen: A Five Year Study. Oman Med J 2009;24:81-83
  14. Fakhre GP, Berland T, Lube MW. One hundred consecutive splenectomies for trauma: is histologic evaluation really necessary? J Trauma 2008;64:1139-41. http://dx.doi.org/10.1097/