Journals / Okmeydanı Tıp Dergisi / 2017 / Cilt: 33 - Sayı: 1

New Prognostic Parameters of Sudden Hearing Loss: Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio

Ani İşitme Kaybı Olan Hastalarda Yeni Prognostik Parametreler: Nötrofil/Lenfosit Oranı ve Platelet/Lenfosit Oranı

Pages
1–5
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: NLR and PLR values may be used as a novel marker that is easily administered in patients with sudden sensorineural hearing loss and obtained with low cost tests.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Sudden hearing loss is a sensorineural hearing loss that develops within three days, leading to a minimum 30 dB hearing loss, involving at least three frequencies.
📊
Key Findings & Data:Material and Methods: 58 patients diagnosed with sudden sensorineural hearing loss were included in our study.
💡
Conclusion & Impact:Conclusion: NLR and PLR values may be used as a novel marker that is easily administered in patients with sudden sensorineural hearing loss and obtained with low cost tests.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Sudden hearing loss is a sensorineural hearing loss that develops within three days, leading to a minimum 30 dB hearing loss, involving at least three frequencies. This study aims to investigate the correlations between sudden sensorineural hearing loss with neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR). Material and Methods: 58 patients diagnosed with sudden sensorineural hearing loss were included in our study. Blood samples and the hearing assessments of the patients were carried out. Then, the patients were divided into 2 groups as "recovered" and "unrecovered" according to their response to the treatment. Results: The mean NLR and PLR values in patients with sudden sensorineural hearing loss were significantly higher than in the control group (p<0.001). In addition, NLR and PLR levels were higher in unrecovered patients compared with recovered patients. Conclusion: NLR and PLR values may be used as a novel marker that is easily administered in patients with sudden sensorineural hearing loss and obtained with low cost tests.

Özet

Amaç: Ani işitme kaybı (AİK) en fazla üç gün içinde aniden gelişen, en az üç frekansı tutan, minimum 30 dB ve üzerindeki sensorinoral işitme kaybıdır. Bu çalışmada, AİK'nın nötrofil lenfosit oranı (NLO) ve platelet lenfosit oranı (PLO) ile olan ilişkisinin değerlendirilmesi amaçlandı. Gereç ve Yöntem: Çalışmaya AİK tanısı konulan 58 hasta dahil edildi. Hastaların kan değerleri ve işitme sonuçları kaydedildi. Ardından hastalar tedaviye verdikleri yanıta göre düzelen ve düzelmeyen olarak iki gruba ayrıldı.Bulgular: Ani işitme kaybı olan hastaların ortalama NLR ve PLR değerleri kontrol grubuna göre anlamlı olarak yüksek bulundu (p<0,001). Buna ek olarak, NLR ve PLR düzeyleri düzelen hastalarla karşılaştırıldığında düzelmeyen hastalarda daha yüksekti.Sonuç: Ani işitme kayıplı hastalarda kolay uygulanabilen ve düşük maliyetli testler ile elde edilen NLO ve PLO değerleri yeni bir belirteç olarak kullanılabilir.

🔖

Cite This Article

AYDOĞDU, İ., YILDIRIM, G., KUMRAL, T. L., SALTÜRK, Z., AYDOĞDU, Z., İNAN, M., UYAR, Y. (2017). New Prognostic Parameters of Sudden Hearing Loss: Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio. Okmeydanı Tıp Dergisi, Cilt: 33 - Sayı: 1, 1–5. https://ajindex.com/articles/291673

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Dallan I, Bruschini L, Nacci A, Bruschini P, Traino C, Rognini F, et al. Transtynpanic steroids as a salvage therapy in sudden hearing loss: preliminary results. ORL J Otorhinolaryngol Relat Spec 2006;68:247-52.
  2. Booth JB. Sudden and Fluctuant sensorineural hearing loss, In: Kerr AG, Editor. Scott Browns Otolaryngology. 6th ed. London: Butterworths-Heinemann 1997;3:1-82
  3. Shikowitz MJ. Sudden sensorineural hearing loss. Med Clin North Am 1991;75:1239-50.
  4. Mattox DE, Simmons FB. Natural history of sudden sensorineural hearing loss. Ann Otol Rhinol Laryngol 1977;86:463-80.
  5. Matthew R, O'Malley, MD, David S. Sudden Hearing Loss. Otolaryngol Clin N Am 2008; 633-49
  6. Ulu S, Ulu MS, Bucak A, Ahsen A, Yucedag F, and Aycicek A. Neutrophil-to-lymphocyte ratio as a new, quick, and reliable indicator for predicting diagnosis and prognosis of idiopathic sudden sensorineural hearing loss. Otology and Neurotology 2013;34:1400-4.
  7. Shiny A, Bibin YS, Shanthirani CS, et al. Association of neutrophil-lymphocyte ratio with glucose intolerance: an indicator of systemic inflammation in patients with type 2 diabetes. Diabetes Technology &Therapeutics 2014;16:524-30.
  8. Seo Y, Jeong Jun, Choi J and Moon In. Neutrophil-tolymphocyte ratio and platelet - to -lymphocyte ratio: Novel markers for diagnosis and prognosis in patients with idiopathic sudden sensorineural hearing loss. Hindawi Publishing Corparation 2014;1:532-50
  9. Siegel LG. The treatment of idiopathic sudden sensorineural hearing loss. Otolaryngologic Clinics of North America 1975;8:467-73
  10. Masuda M, Kanzaki S, Minami S, et al. Correlations of inflammatory biomarkers with the onset and prognosis of idiopathic sudden sensorineural hearing loss. Otology & Neurotology 2012;33:1142-50.
  11. Son EJ, Bang JH, Kang JG. Anterior inferior cerebellar artery infarction presenting with sudden hearing loss and vertigo. Laryngoscope 2007;117:556-8.
  12. Kallinen J, Laurikainen E, Laippala P, Grenman R. Sudden deafness: a comparision of anticoagulant therapy and carbogen inhalation therapy. An Otol Rhinol Laryngol 1997;106:22-6.
  13. Rudack C, Langer C, Stoll W, Rust S, andWalter M. Va