Journals / Namık Kemal Tıp Dergisi / 2021 / Cilt: 9 - Sayı: 1

The 33-year Retrospective Analysis of Esophageal Carcinomas: Cerrahpaşa Experience

Özefagus Karsinomlarının 33 Yıllık Retrospektif Analizi: Cerrahpaşa Deneyimi

Pages
67–71
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Patient-specific treatment should be planned with a multidisciplinary approach.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Esophageal cancer is a fatal disease where the majority of patients are diagnosed at an advanced stage.
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Key Findings & Data:In this study, we aimed to present the demographic and clinicopathological characteristics of patients who were operated for esophageal cancer.
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Conclusion & Impact:Patient-specific treatment should be planned with a multidisciplinary approach.
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Esophageal cancer is a fatal disease where the majority of patients are diagnosed at an advanced stage. In this study, we aimed to present the demographic and clinicopathological characteristics of patients who were operated for esophageal cancer. Materials and Methods: A total of 847 patients who underwent surgery, chemoradiotherapy, or palliative procedures for esophageal pathology between the years of 1985 and 2018 were retrospectively analyzed. Age, gender, tumor location, histopathology, surgical technique, and chemoradiotherapy history of patients were analyzed. Results: In the study, 488 patients were male (60.5%) and 319 were female (39.5%). The ratio of males and females was 1.52. The average age was 58.6 years, and 80.1% were older than 50 years. The most common pathological material obtained was squamous cell carcinoma (67.5%), followed by adenocarcinoma (27.7%). Total esophagectomy was performed in 435 patients; distal esophagectomy was performed in 38 patients. Transhiatal esophagectomy (n=271, 62.2%) was the most common procedure that was performed. Conclusion: Esophagectomy is the primary treatment modality for esophageal cancers. When determining the optimal treatment, appropriate patient selection, staging, and risk assessment should be made. Patient-specific treatment should be planned with a multidisciplinary approach.

Özet

Amaç: Özefagus kanseri, hastaların çoğunun ileri evrede teşhis edildiği ölümcül bir hastalıktır. Bu çalışmada özefagus kanseri nedeniyle ameliyat edilen hastaların demografik ve klinikopatolojik özelliklerini sunmayı amaçladık. Gereç ve Yöntem: 1985-2018 yılları arasında özefagus patolojisi nedeniyle cerrahi, kemoradyoterapi veya palyatif prosedürler uygulanan toplam 847 hasta retrospektif olarak incelendi. Hastaların yaş, cinsiyet, tümör yerleşimi, histopatolojisi, cerrahi teknik ve kemoradyoterapi öyküleri incelendi. Bulgular: Çalışmada 488 hasta erkek (%60,5) ve 319 hasta kadındı (%39,5). Katılımcıların yaş ortalaması 58,6 olup, %80,1’i 50 yaşın üzerindeydi. Erkeklerin ve kadınların oranı sırasıyla %60,5 ve %39,5 idi. Elde edilen en yaygın patoloji materyali skuamöz hücreli karsinom (%67,5), ardından adenokarsinomdu (%27,7). Toplam özefajektomi 435 hastaya yapıldı ve 38 hastaya distal özefajektomi yapıldı. Transhiatal özefajektomi (n=271, %62,2) en sık yapılan işlemdi. Sonuç: Özefajektomi, özefagus kanserleri için birincil tedavi yöntemidir. Optimal tedaviyi belirlerken uygun hasta seçimi, evreleme ve risk değerlendirmesi yapılmalıdır. Hastaya özel tedavi multidisipliner bir yaklaşımla planlanmalıdır.

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Cite This Article

ULUDAĞ, S. S., AKINCI, O., ERGÜN, S., ERGİNÖZ, E., ŞANLI, A. N., KEPİL, N., AYAN, F., ÖZÇELİK, M. F., ZENGİN, A. K. (2021). The 33-year Retrospective Analysis of Esophageal Carcinomas: Cerrahpaşa Experience. Namık Kemal Tıp Dergisi, Cilt: 9 - Sayı: 1, 67–71. https://ajindex.com/articles/288949

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