SavedAdd your journal

Journals / Osmangazi Tıp Dergisi / 2021 / Cilt: 43 - Sayı: 3

A Case with Kounis Syndrome After the Administration of Metoclopramid

Metoklopramide Bağlı Gelişen Kounis Sendromu Olgusu

Engin OZAKİN
Volkan ERCAN
KADİR UĞUR MERT
Pages
283–287
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We report the case of 71-year-old man with no coronary risk factors or family history of coronary artery disease, who developed Kounis syndrome after the administration of metoclopramide for nausea.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Kounis syndrome is characterized by a symptoms that cause unstable vasospastic or non-vasospastic angina secondary to a hypersensitivity reactions.
📊
Key Findings & Data:After identification by Kounis in 1991, this syndrome includes a series of mast cell activation disorders associated with acute coronary syndrome.
💡
Conclusion & Impact:We report the case of 71-year-old man with no coronary risk factors or family history of coronary artery disease, who developed Kounis syndrome after the administration of metoclopramide for nausea.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kounis · miyokard enfarktüsü · allerji

Abstract

Kounis syndrome is characterized by a symptoms that cause unstable vasospastic or non-vasospastic angina secondary to a hypersensitivity reactions. After identification by Kounis in 1991, this syndrome includes a series of mast cell activation disorders associated with acute coronary syndrome. There are many triggering factors, including reactions to multiple medications, foods such as fish, tomato, fruits, bee stings poison ivy, viper venom, shellfish and coronary stents. We report the case of 71-year-old man with no coronary risk factors or family history of coronary artery disease, who developed Kounis syndrome after the administration of metoclopramide for nausea.

Özet

Kounis sendromu, aşırı duyarlılık reaksiyonlarına sekonder kararsız vazospastik veya vazospastik olmayan anjinaya neden olan semptomlarla karakterizedir. Kounis tarafından 1991'de tanımlandıktan sonra bu sendrom, akut koroner sendromla ilişkili bir dizi mast hücresi aktivasyon bozukluğunu içerir. Çoklu ilaçlara verilen reaksiyonlar, balık, domates, meyve, arı sokması zehirli sarmaşık, engerek zehiri, kabuklu deniz ürünleri gibi gıdaları ve koroner stentleri içeren birçok tetikleyici faktör vardır. Olgumuzda, bulantı için metoklopramid uygulandıktan sonra Kounis sendromu gelişen koroner risk faktörü veya aile öyküsünde koroner arter hastalığı bulunmayan 71 yaşında erkek hastayı sunuyoruz.

🔖

Cite This Article

OZAKİN, E., ERCAN, V., MERT, K. U. (2021). A Case with Kounis Syndrome After the Administration of Metoclopramid. Osmangazi Tıp Dergisi, Cilt: 43 - Sayı: 3, 283–287. https://ajindex.com/articles/287637

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Kounis, N.G., Coronary hypersensitivity disorder: the Kounis syndrome. Clin Ther, 2013. 35(5): p. 563-71
  2. Kounis, N.G. and G.M. Zavras, Allergic angina and allergic myocardial infarction. Circulation, 1996. 94(7): p. 1789
  3. Kounis, N.G., N.D. Grapsas, and J.A. Goudevenos, Unstable angina, allergic angina, and allergic myocardial infarction. Circulation, 1999. 100(25): p. e156
  4. Pfister, C.W. and S.G. Plice, Acute myocardial infarction during a prolonged allergic reaction to penicillin. Am Heart J, 1950. 40(6): p. 945-7
  5. Schultheiss, E., [Clinical Aspects of Allergic Heart Diseases]. Dtsch Med J, 1964. 15: p. 15-8
  6. Goto, M., et al., Chronic atherosclerotic mesenteric ischemia that started to develop symptoms just after anaphylaxis. Case Rep Gastroenterol, 2012. 6(2): p. 300-8
  7. Gonzalez-de-Olano, D., et al., Mast cell activation disorders presenting with cerebral vasospasm-related symptoms: a "Kounis-like" syndrome? Int J Cardiol, 2011. 150(2): p. 210-1
  8. Kounis, N.G., Kounis syndrome: an update on epidemiology, pathogenesis, diagnosis and therapeutic management. Clin Chem Lab Med, 2016. 54(10): p. 1545-59
  9. Renda, F., et al., Kounis Syndrome: An analysis of spontaneous reports from international pharmacovigilance database. Int J Cardiol, 2016. 203: p. 217-20
  10. Kounis, N.G., et al., Kounis syndrome: a new twist on an old disease. Future Cardiol, 2011. 7(6): p. 805-24
  11. Biteker, M., Current understanding of Kounis syndrome. Expert Rev Clin Immunol, 2010. 6(5): p. 777-88
  12. Kounis, N.G., Serum tryptase levels and Kounis syndrome. Int J Cardiol, 2007. 114(3): p. 407-8
  13. Zavras, G.M., et al., Kounis syndrome secondary to allergic reaction following shellfish ingestion. Int J Clin Pract, 2003. 57(7): p. 622-4
  14. Lippi, G., et al., Cardiac troponin I is increased in patients admitted to the emergency department with severe allergic reactions. A case-control study. Int J Cardiol, 2015. 194: p. 68-9
  15. Goto, K., et al., Myocardial scintigraphic evidence of Kounis syndrome: what is the aetiology of acute coronary syndrome? Eur Heart J, 2016. 37(14): p. 1157
  16. Okur, A., et al., The utility of cardiac magnetic resonance imaging in Kounis syndrome. Postepy Kardiol Interwencyjnej, 2015. 11(3): p. 218-23
  17. Ramey, J.T. and R.F. Lockey, Allergic and nonallergic reactions to nitroglycerin. Allergy Asthma Proc, 2006. 27(3): p. 273-80.