AI Summary & Key Takeaways
AI InsightFenthion poisoning and intermediate syndrom have been reviewed and discussed because of a case who had been supported by mechanical ventilation for 38 days and treated with increasing doses of atropin as high as 1500 mg/day, and discharged in the 60 th day with the sequel of axonal degeneration.
📌 3 Key Takeaways
Abstract
Fenthion is the most dangerous organophosphor insecticid drug which depresses all isomers of serum choline esterase irreversibly for 4-40 days. Intermediate syndrom which has characteristics of weakness of neck, limb and respiratory muscles and cranial motor nerve palsy, manifest in 5-10 % of the cases of fenthion poisoning. Fenthion poisoning and intermediate syndrom have been reviewed and discussed because of a case who had been supported by mechanical ventilation for 38 days and treated with increasing doses of atropin as high as 1500 mg/day, and discharged in the 60 th day with the sequel of axonal degeneration.
Özet
Fenthion, serum kolinesterazının bütün bantlarını 4-40 gün boyunca irrreversibl olarak deprese eden en tehlikeli organofosfor insektisid ilaçtır. Fenthion zehirlenmesi olgularının % 5-10'unda, boyun, solunum ve uyluk kaslarında zayıflık ve motor kraniyal sinir palsisi ile karakterize intermediate sendrom ortaya çıkmaktadır. 38 gün ventilatör desteği ve 1500 mg/gün'e kadar yüksek dozlarda atropin tedavisi sonucu, 60. günde aksonal dejenerasyon sekeliyle taburcu ettiğimiz bir olgu nedeniyle fenthion zehirlenmesi ve intermediate sendrom gözden geçirilmiş ve tartışılmıştır.