Journals / Medeniyet Medical Journal / 2018 / Cilt: 33 - Sayı: 1

Auxiliary tests in the diagnosis of prostate cancer

Prostat kanseri tanısında yardımcı testler

Pages
47–53
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, the biomarkers and imaging methods used for the diagnosis and screening of prostate cancer will be evaluated in the light of the current literature.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Prostate-specific antigen (PSA) is the most commonly used marker in the screening of prostate cancer which is the most common solid tumor in men.
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Key Findings & Data:Although PSA is specific for prostate, its specificity for prostate cancer is low and its false negative rate is high.
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Conclusion & Impact:In this review, the biomarkers and imaging methods used for the diagnosis and screening of prostate cancer will be evaluated in the light of the current literature.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Prostate-specific antigen (PSA) is the most commonly used marker in the screening of prostate cancer which is the most common solid tumor in men. Although PSA is specific for prostate, its specificity for prostate cancer is low and its false negative rate is high. With PSA-based screening, disease-specific mortality has declined in recent years, but this has led some patients to receive overdiagnosis, unnecessary biopsies and treatment. In recent years, new biomarkers have been developed that can provide specific and early diagnosis of prostate cancer to resolve these problems. In this review, the biomarkers and imaging methods used for the diagnosis and screening of prostate cancer will be evaluated in the light of the current literature.

Özet

Erkeklerde en sık görülen solid tümör olan prostat kanserinin taramasında günümüzde halen en sık belirteç olarak prostat spesifik antijen (PSA) kullanılmaktadır. PSA, prostata spesifik olmasına rağmen, prostat kanseri için spesifitesi düşüktür ve yanlış negatiflik oranı yüksektir. PSA bazlı taramalar ile hastalığa özgü mortalite son yıllarda azalmış ancak bu bazı hastaların fazladan tanı almasına, gereksiz biyopsilere ve tedaviye maruz kalmasına neden olmuştur. Bu gibi sorunları giderilmesi amacıyla son yıllarda prostat kanserine spesifik ve erken tanı olanağı sunabilen biyomarkerler geliştirilmiştir. Bu derlemede prostat kanseri tanı ve taraması için kullanımda olan biyomarkerlar ve görüntüleme yöntemleri güncel literatür eşliğinde değerlendirilecektir.

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Cite This Article

DANACIOĞLU, Y. O., EROL, B., ÇAŞKURLU, T. (2018). Auxiliary tests in the diagnosis of prostate cancer. Medeniyet Medical Journal, Cilt: 33 - Sayı: 1, 47–53. https://ajindex.com/articles/283328

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