Journals / Medeniyet Medical Journal / 2018 / Cilt: 33 - Sayı: 4

Foot pain frequently associated with vitamin D deficiency: Bone marrow edema syndrome

Pages
263–268
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

For that reason, patients need to be investigated in that way.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Bone marrow edema syndrome (BMES) describes non-specific, ill-defined areas of hypo intense and hyper intense sig-nal on T1 and T2 sequences, respectively.
📊
Key Findings & Data:Method: We evaluated 19 feet of 17 patients who applied to our clinic between January 2014 and December 2016.
💡
Conclusion & Impact:For that reason, patients need to be investigated in that way.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Özet

Aim: Bone marrow edema syndrome (BMES) describes non-specific, ill-defined areas of hypo intense and hyper intense sig-nal on T1 and T2 sequences, respectively. BMES has unknown etiology and resolves without sequel. In this study, we aimed to evaluate the initial clinical and radiological features and clinical course of patients with standing BMES. Method: We evaluated 19 feet of 17 patients who applied to our clinic between January 2014 and December 2016. X-Ray and MRI were taken in patients with clinical suspicion of BMES. Initial vitamin-D levels, hemogram, sedimentation, C-reactive protein (CRP), rheumatoid factor (RF) and Anti-CCP values of patients were evaluated. After the diagnosis, indomethacin and vitamin-D therapy and weight-bearing protection with double crutches was given for 6 weeks. Result: All patients mentioned that sudden onset of pain. The mean duration of symptoms was 7.12(2-20) months. Mean se-rum 25(OH)D level was 14 IU, sedimentation values were slightly higher in 7 patients, CRP, RF and Anti-CCP values were normal. BMES mostly detected in talus. The mean AOFAS score of the patients was 63 and the last control was 92. Conservative tre-atments should be considered as the first-line treatment option in BMES. Conclusion: The importance of laboratory tests in BMES should not be forgotten. Vitamin-D may play a role in the etiology of the disease. For that reason, patients need to be investigated in that way.

🔖

Cite This Article

ECEVİZ, E., ÇEVİK, B., BULUT, G., BAYSAL, Ö., GÜLABİ, D., ÇEÇEN, G. S. (2018). Foot pain frequently associated with vitamin D deficiency: Bone marrow edema syndrome. Medeniyet Medical Journal, Cilt: 33 - Sayı: 4, 263–268. https://ajindex.com/articles/283316

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Orr JD, Sabesan V, Major N, Nunley J. Painful bone marrow edema syndrome of the foot and ankle. Foot & Ankle Inter-national. 2010;31(11):949-53.
  2. Radke S, Vispo-Seara J, Walther M, Ettl V, Eulert J. Transient bone marrow oedema of the foot. International Orthopae-dics. 2001;25(4):263-7.
  3. Curtiss PH, Kincaid WE. Transitory demineralization of the hip in pregnancy. JBJS Case Connector. 1959 (7):1327-33
  4. Wilson A, Murphy W, Hardy D, Totty W. Transient osteoporosis: transient bone marrow edema? Radiology. 1988;167(3):757-60.
  5. Naides S, Resnick D, Zvaifler N. Idiopathic regional osteo-porosis: a clinical spectrum. The Journal of Rheumatology. 1985;12(4):763-8
  6. Mirghasemi SA, Trepman E, Sadeghi MS, Rahimi N, Rashidi-nia S. Bone marrow edema syndrome in the foot and ankle. Foot & Ankle International. 2016;37(12):1364-73.
  7. Orth P, Anagnostakos K. Coagulation abnormalities in osteo-necrosis and bone marrow edema syndrome. Orthopedics. 2013;36(4):290-300.
  8. Rodriguez S, Paniagua O, Nugent KM, Phy MP. Regional tran-sient osteoporosis of the foot and vitamin C deficiency. Clini-cal Rheumatology. 2007;26(6):976-8.
  9. Horas K, Fraissler L, Maier G, Jakob F, Seefried L, Konrads C, et al. High prevalence of vitamin D deficiency in patients with bone marrow edema syndrome of the foot and ankle. Foot & Ankle International. 2017;38(7):760-6.
  10. Hofmann S, Engel A, Neuhold A, Leder K, Kramer J, Plenk H. Bone-marrow oedema syndrome and transient osteoporosis of the hip. An MRI-controlled study of treatment by core de-compression. Bone & Joint Journal. 1993;75(2):210-6
  11. Hofmann S, Schneider W, Breitenseher M, Urban M, Plenk Jr H. “Transient osteoporosis” as a special reversible form of femur head necrosis. Der Orthopade. 2000;29(5):411-9
  12. Mayerhoefer M, Kramer J, Breitenseher M, Norden C, Vakil-Adli A, Hofmann S, et al. Short-term outcome of painful bone marrow oedema of the knee following oral treatment with iloprost or tramadol: results of an exploratory phase II study of 41 patients. Rheumatology. 2007;46(9):1460-5.
  13. Meizer R, Radda C, Stolz G, Kotsaris S, Petje G, Krasny C al. MRI-controlled analysis of 104 patien