SavedAdd your journal

Journals / Mathematical and Computational Applications / 2014 / Cilt: 19 - Sayı: 2

Estimation of mucus clearance in pulmonary airways by means of a regression model

Shahriar Shamil UULU
Halil Rıdvan ÖZ
Ferhat KARACA
Cahit A. EVRENSEL
Pages
144–151
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Simulations revealed several important data like direct relation between velocity and clearance and indirect relation between angle and clearance.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:- In this study, a multivariate regression analysis was performed on a dataset obtained from experimental tracheal model for mucus clearance in pulmonary airways.
📊
Key Findings & Data:Several simulations have been done to verify the validity of the generated regression model.
💡
Conclusion & Impact:Simulations revealed several important data like direct relation between velocity and clearance and indirect relation between angle and clearance.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

- In this study, a multivariate regression analysis was performed on a dataset obtained from experimental tracheal model for mucus clearance in pulmonary airways. Several simulations have been done to verify the validity of the generated regression model. In general, the clearance of mucus in the airways is achieved by the beating action of cilia inside the serous layer which is the primary means of removing inhaled particulates and airway debris from airways in healthy people. In this study, two types of mucus simulants are used in the experimental setup. Clearance distances of a teardrop shape simulant are measured for different velocities, slope angles and surfaces properties. On the obtained data by applying several genuine transformations we developed a multiple regression model that is able to predict clearance up to 86% accuracy. Simulations revealed several important data like direct relation between velocity and clearance and indirect relation between angle and clearance.

🔖

Cite This Article

UULU, S. S., ÖZ, H. R., KARACA, F., EVRENSEL, C. A. (2014). Estimation of mucus clearance in pulmonary airways by means of a regression model. Mathematical and Computational Applications, Cilt: 19 - Sayı: 2, 144–151. https://ajindex.com/articles/279785

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Z.D. Xu, D.H. Jia, X.C. Zhang, Performance tests and mathematical model considering magnetic saturation for magnetorheological damper, Journal of Intelligent Matherial Systems and Structures 23(12), 1331-1349, 2012
  2. X.C. Guan, P.F. Guo, Modeling of Magnetorheological Dampers Utilizing a General Non-linear Model, Journal of Intelligent Material Systems and Structures 22(5), 435- 442, 2011
  3. H.R. Öz, B. Karlık, Evrensel CA, Applications of Artificial Neural Networks Method in Mucus Clearance in Pulmonary Airways, International Journal of Natural and Engineering Sciences 3(2), 14-16, 2009
  4. A. Fuchs, Q. Zhang, J. Elkins, F. Gordaninejad, C.A. Evrensel, Development and characterization of magnetorheological elastomers, Journal of Applied Polymer Science 105(5), 2497-2508, 2007
  5. C.A. Evrensel, P.E. Krumpe, A.A. Hassan, H.R. Öz, Effect of slope and viscoelastic behavior on the clearance of mucus simulant in tracheal models, Proceedings of 6th Biennial Conference on Engineering Systems Design and Analysis 2002, Istanbul, TURKEY
  6. P.E. Krumpe, H.R. Öz, C.A. Evrensel, A.A. Hassan, Why do we sit up to cough? The benefits of vertical posture during cough clearance, Chest 2001 Annual Meeting, 120, 236-237A, 2001, November 4-8, Pennsylvania Convention Center Philadelphia, Pennsylvania, USA
  7. P.W. Scherer, L. Burtz, Fluid mechanics experiments relevant to coughing, Journal of Biomechanics 11, 183-187, 1978
  8. M. King, The role of mucus viscoelasticity in cough clearance, Journal of Biorheology 6, 589-597, 1987
  9. A.A. Hassan, CA Evrensel, PE Krumpe, Interaction of airflow with viscoelastic gel in endotracheal tubes, Advances in Bioengineering Journal 48, 231-232, 2000
  10. C.A. Evrensel, H.R. Öz, P.E. Krumpe, A.A. Hassan, Simulated mucus clearance in horizontal vs. vertically inclined rigid tracheal model, Proceedings of International Mechanical Engineering Congress and Exposition 2001, November 11-16, New York, NY, USA
  11. M. King, Experimental models for studying mucociliary clearance, European Respiratory Journal 11, 222, 1998
  12. M. King, P.T. Macklem, Rheological properties of microliter quantities of normal mucus, Journal of Applied Physiology: Respiratory Environmental and Exercise Physiology 42, 797-802, 1977
  13. H. D. Margaret, Data Mining Introductory and Advanced Topics, Prentice Hall, ISBN-0-13-088892-3, 54-80, 2003
  14. B.K. Rubin, O. Ramirez, J. Mellor, Cough and Ciliary Clearability of Sputum is Dependent on its Adhesivity and not on