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Journals / Medical Network Klinik Bilimler ve Doktor / 2000 / Cilt: 6 - Sayı: 1

The effect of long term continously estrogen and progesteron replacement therapy on endometrial histology and uterine bleeding in postmenopausal women

Postmenopozal kadınlarda uzun süreli kontinü estrogen ve progesteron replasman tedavisinin endometrial histoloji ve uterin kanama üzerine etkileri

Cavidan GÜLERMAN
Perran MORÖY
Havva ÇELİKKANAT
Levent ALAYBEYOĞLU
MELİKE DOĞANAY
Mete TAN
Oya GÖKMEN
Pages
116–118
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In seventy percent of amenoreic patients endometrial biopsy revealed atrofic histology: CONCLUSIONS: Long term continuous estrogen progestin hormone replacement therapy diminished uterine bleeding and induced inactive endometrium formation in postmenopausal women: thus it seems to be a safe and effective treatment modality.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVES: To evaluate the effect of long term continously estrogen and progesteron replacement therapy on endometrial histology and uterine bleeding in postmenopausal women.
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Key Findings & Data:METHODS: Endometrial thickness were followed by endovaginal ultrasonograpy in 23 postmenopausal women taking continuous estrogen and progestin replacement therapy during the past 5 years.
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Conclusion & Impact:In seventy percent of amenoreic patients endometrial biopsy revealed atrofic histology: CONCLUSIONS: Long term continuous estrogen progestin hormone replacement therapy diminished uterine bleeding and induced inactive endometrium formation in postmenopausal women: thus it seems to be a safe and effective treatment modality.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Uterus kanamaları · İlaç tedavisi · kombinasyon

Abstract

OBJECTIVES: To evaluate the effect of long term continously estrogen and progesteron replacement therapy on endometrial histology and uterine bleeding in postmenopausal women. METHODS: Endometrial thickness were followed by endovaginal ultrasonograpy in 23 postmenopausal women taking continuous estrogen and progestin replacement therapy during the past 5 years. Endometrial biopsy samliles were taken periodically. RESUL TS: In the thirty percent of cases, irregular vaginal bleeding occured after amenoreic period was induced. In seventy percent of amenoreic patients endometrial biopsy revealed atrofic histology: CONCLUSIONS: Long term continuous estrogen progestin hormone replacement therapy diminished uterine bleeding and induced inactive endometrium formation in postmenopausal women: thus it seems to be a safe and effective treatment modality.

Özet

AMAÇ: Uzun süreli kont i nü hormon replasman tedavisinin endometrial histoloji ve isterin kanama üzerine etkilerini değerlendirmektir. YÖNTEM: 5 yıl boyunca sürekli kontinü hormon replasman tedavisi alan 23 postmenopozal kadın izlendi. Endometrial kalınlıklar endovaginal ultrasonografi ile periyodik olarak ölçüldü. Periyodik olarak alınan endometrial biyopsi sonuçları değerlendirildi. BULGULAR: Vakaların %30'nnda amenore sağlandıktan sonraki dönemlerde irregüler itlerin kamıma meydana geldi. Amenore sağlanan %70 'lik gruptaki kadınlardan alınan endometrial biyopsi örneklerinde atrofik histoloji saptandı. SONUÇ: Postmenopozal kadınlarda uzun süre kontinü estrogen ve progesteron hormon rejimi kullanılması uterin kanamayı azaltmakla ve inaktif endometriumun gelişmesine yol açmaktadır.

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Cite This Article

GÜLERMAN, C., MORÖY, P., ÇELİKKANAT, H., ALAYBEYOĞLU, L., DOĞANAY, M., TAN, M., GÖKMEN, O. (2000). The effect of long term continously estrogen and progesteron replacement therapy on endometrial histology and uterine bleeding in postmenopausal women. Medical Network Klinik Bilimler ve Doktor, Cilt: 6 - Sayı: 1, 116–118. https://ajindex.com/articles/279634

References (6)

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