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Journals / Medical Network Klinik Bilimler ve Doktor / 2002 / Cilt: 8 - Sayı: 5

Frequency of the cytomegalalovirus in the diabetic and non-diabetic patients with coronary heart disease

Diyabetik ve diyabetik olmayan koroner kalp hastalarında cytomegalovirus sıklığı

Fatih YALÇIN
Hatice KARAKÖSE
Adnan GÖKÇEL
Fatma YİĞİT
Hülya YALÇIN
Fuat YAPAR
Mehmet Emin KORKMAZ
Haldun MÜDERRİSOĞLU
Pages
563–567
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, because of relatively limited number of the study group, these results need to support by studies with larger study groups.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: It is known that incidence of atherosclerosis is high and immunologic responce to viral antigens is impaired in diabetic patients.
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Key Findings & Data:This stdudy was designed to investigate whether cytomegalovirus (CMV) infection which is a potential risk factor for coronary atery disease (CAD) leads to increased CAD in diabetic patients.
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Conclusion & Impact:However, because of relatively limited number of the study group, these results need to support by studies with larger study groups.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Sitomegalovirüs · Koroner anjiyografi · Diabetes mellitus

Abstract

OBJECTIVE: It is known that incidence of atherosclerosis is high and immunologic responce to viral antigens is impaired in diabetic patients. This stdudy was designed to investigate whether cytomegalovirus (CMV) infection which is a potential risk factor for coronary atery disease (CAD) leads to increased CAD in diabetic patients. MATERIAL AND METHODS: 26 diabetic patiens (mean age: 58) with CAD and 25 non-diabetics were included into the study (36 men, 15 women). CMV antibody titer (1g G and M) were decected. RESULTS: CMV antibody positivity was 100% in diabetics and 96%non-diabetics and diifference between two groups was not statistically significant. CMV prevalence in men and women was also similar. CONCLUSION: CMV prevalance was remankably high on the whole group. However, because of relatively limited number of the study group, these results need to support by studies with larger study groups.

Özet

AMAÇ:Diyabetik hastalarda ateroskleroz insidansının yüksek olduğu, ayrıca viral antijenlere immün cevabın bozuk olduğu bilinmektedir. Koroner arter hastalığının (KAH) potansiyel risk faktörlerinden biri olan cytomegalovirus (CMV) infeksiyonunun, diyabetiklerdeki artmış koroner arter hastalığından sorumlu olup olmadığını araştırmak amacıyla bir çalışma planlandı. GEREÇ VE YÖNTEM:Koroner aterosklerozu gösterilmiş, yaş ortalaması 58 olan 26 diyabetik ve 25 nondiyabetik hasta çalışmaya alındı (36 erkek, 15 kadın). Hastalarda CMV IgG ve IgM antikor titreleri ölçüldü. BULGULAR: CMV antikor pozitifliği diyabetik grupta %100, diyabetik olmayan grupta %96 bulundu; anlamlı farklılık saptanmadı. Kadın ve erkeklerde CMV prevalansında farklılık yoktu. SONUÇ: Tüm gruplarda CMV prevalansının çok yüksek olması dikkat çekiciydi.Ancak çalışma grubu nisbeten küçük olduğundan, sonuçların daha geniş bir çalışma grubunda yapılacak çalışmalarla desteklenmesine ihtiyaç vardır.

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Cite This Article

YALÇIN, F., KARAKÖSE, H., GÖKÇEL, A., YİĞİT, F., YALÇIN, H., YAPAR, F., KORKMAZ, M. E., MÜDERRİSOĞLU, H. (2002). Frequency of the cytomegalalovirus in the diabetic and non-diabetic patients with coronary heart disease. Medical Network Klinik Bilimler ve Doktor, Cilt: 8 - Sayı: 5, 563–567. https://ajindex.com/articles/279168

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