Relationship between newborn macrosomia and abnormal glucose tolerance

Objective & Hypothesis:Objective: The purpose of this study was to examine the relationship between newborn macrosomia and plasma glucose profile, in both aglucose challenge test positive, oral glucose tolerance test negative group.

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Key Findings & Data:Material and Method: Pregnant women (n=727) who attended the antenatal clinic and delivered at the hospital were recieved 50gr glucose challenge test.

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Conclusion & Impact:Conclusion: The overall prevelance of glucose abnormalities during pregnancy was 25.28%.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Fetal makrosomi · Glukoz tolerans testi · Diabetes

Abstract

Objective: The purpose of this study was to examine the relationship between newborn macrosomia and plasma glucose profile, in both aglucose challenge test positive, oral glucose tolerance test negative group. Material and Method: Pregnant women (n=727) who attended the antenatal clinic and delivered at the hospital were recieved 50gr glucose challenge test. Oral glucose tolerance test was performed to the women with positive glucose challenge test. Gestatıonal age at delivery,route of delivery, weights of infants were collected from patients charts. Results: Nineteen women were diagnosed with gestational diabetes (2.61%), 168 had positive glucose challenge, but negative oral glucose tolerance test (22.97%). We collected the patients charts of this 168 women. Macrosomia occurred in 20 infants (11.9%), 15 were between 4000 and 4500gr and 5 were above 4500gr (2.97%). Conclusion: The overall prevelance of glucose abnormalities during pregnancy was 25.28%. Glucose intolerance in this group was associated with high macrosomia rate.

Özet

Amaç: Bu çalışmanın amacı 100 gr oral glukoz tolerans testi negatif fakat 50gr oral glukoz testi pozitif grupta yeni doğan makrosomisi ve glukoz profili arasındaki ilişkiyi incelemektir. Gereç ve Yöntem: Hastanemiz antenatal kliniğine başvuran 727 gebe kadına 50gr OGT yapıldı. Sonuç pozitif olanlara 100gr oral glukoz tolerans testi uygulandı. Doğum sırasındaki gestasyonel yaş, doğum şekli ve yeni doğanların kilosu hastaların dosyalarından incelendi. Bulgular: 19 gebeye gestasyonel diabetes mellitus tanısı konuldu. (%2.61) 168 gebenin 50gr oral glukoz testi pozitif fakat 100gr oral glukoz tolerans testi negatif bulundu ve glukoz toleransı bozuk grup olarak sınıflandırıldı (%22.97). Glukoz toleransı bozuk grubun doğum dosyaları incelendi. 20 yeni doğan makrozomik bulundu. (%11.9) 15'i 4000-4500 arası ve 5'ide 4500gr üstü idi. Sonuç: Toplam glukoz anormalliği %25.28 bulundu. Glukoz toleransı bozuk olan grupta ise makrozomi oranı fazla idi.

Keywords

Fetal makrosomi Glukoz tolerans testi Diabetes gestasyonel Glukoz intoleransı Fetal Macrosomia Glucose Tolerance Test Gestational Glucose Intolerance

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Cite This Article

YÜKSEL, B., ÇELEN, Ş., BAYAR, D., DANIŞMAN, N. (2003). Relationship between newborn macrosomia and abnormal glucose tolerance. Medical Network Klinik Bilimler ve Doktor, Cilt: 9 - Sayı: 4, 485–487. https://ajindex.com/articles/279160

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