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Journals / Medical Network Klinik Bilimler ve Doktor / 2004 / Cilt: 10 - Sayı: 1

The factors affecting morbidity and mortality in severe preeclampsia and HELLP syndrome cases

Şiddetli preeklampsi, eklampsi ve HELLP sendromunda morbidite ve mortaliteyi etkileyen faktörler

S. Cansun DEMİR
Erdal CANDAN
Cüneyt EVRÜKE
F. Tuncay ÖZGÜNEN
İbrahim F. ÜRÜNSAK
Oktay KADAYIFÇI
Pages
96–100
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Also there was statistically significant relation between maternal complications and liver function tests, LDH levels and low platelet levels.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study is to evaluate the prognostic factors affecting morbidity and mortality in severe preeclampsia, eclampsia and Hellp syndrome cases.
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Key Findings & Data:Materials and Methods: In this study 2245 cases who delivered in Çukurova University Faculty of Medicine Department of Obstetrics and Gynecology between 01.01.2000 and 31.12.2000 were evaluated retrospectively.
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Conclusion & Impact:Also there was statistically significant relation between maternal complications and liver function tests, LDH levels and low platelet levels.
🔬Design:Research Article
📍Scope:2000 Verileri
⚙️Variables:Preeklampsi · Eklampsi · Hastalık oranı

Abstract

Objective: The aim of this study is to evaluate the prognostic factors affecting morbidity and mortality in severe preeclampsia, eclampsia and Hellp syndrome cases. Materials and Methods: In this study 2245 cases who delivered in Çukurova University Faculty of Medicine Department of Obstetrics and Gynecology between 01.01.2000 and 31.12.2000 were evaluated retrospectively. Ninety -three cases had severe preeclampsia, 26 cases eclampsia, 19 cases HELLP syndrome and 6 cases with eclampsia and HELLP syndrome were included into this study. In this study the pregnancy induced hypertension cases were evaluated retrospectively for the socioeconomic status, obstetrical history, biochemical parameters and maternal complications. Results: In this study the prevalance of preeclampsia was 20.1% (453/2245), the prevalance of severe preeclampsia,eclampsia and Hellp syndrome was 6.4% (144/2245). These ratios are higher than the English literature. The complication rate was 38 % in severe preeclampsia cases. Among the severe preeclampsia cases 32 had eclampsia (22.1%) and 25 had Hellp syndrome (17.3%). Conclusion: The most important biochemical marker for the maternal mortality is bilirubin levels. The maternal mortality was statistically higher in the cases with jaundice. Also there was statistically significant relation between maternal complications and liver function tests, LDH levels and low platelet levels.

Özet

Amaç: Şiddetli preeklampsi, eklampsi ve HELLP Sendromu olgularında morbidite ve mortaliteyi etkileyen prognostik faktörlerin değerlendirilmesidir. Gereç ve Yöntem: Bu çalışmada, Ç.Ü.T.F. Kadın Hastalıkları ve Doğum A.B.D.'da 01.01.2000 ve 31.12.2000 tarihleri arasında doğum yapan 2245 olgu retrospektif olarak incelendi. 93 olgu şiddetli preeklampsi, 26 olgu eklampsi, 19 olgu HELLP sendromu ve 6 olgu ise eklampsi + HELLP sendromu tanısı ile çalışmaya dahil edildi. Çalışmada gebeliğe bağlı şiddetli hipertansiyonu bulunan olgular sosyoekonomik düzey, obstetrik öykü, biyokimyasal parametreler ve maternal komplikasyonlar yönünden retrospektif olarak incelenmiştir. Bulgular: Çalışmamızda preeklampsi oranı %20.1 (453/2245) olarak belirlenmiş olup şiddetli preeklampsi, eklampsi ve HELLP sendromu oranı ise %6.4 (144/2245) olarak bulunmuştur. Bu oran batı toplumlarına ait literatürün çok üzerindedir. Şiddetli preeklampsili olgularda komplikasyon oranı %38 olarak bulunmuştur. Şiddetli preeklampsili olguların 32'sinde (%22.1) eklampsi, 25'inde (%17.3) HELLP sendromu görülmüştür. Sonuç: Maternal mortalite ile ilişkili en önemli biyokimyasal belirtecin bilirubin olduğu gözlenmiştir.(p=0.007) İkteri olan olguların maternal mortalitesi yüksek bulunmuştur. Ayrıca karaciğer fonksiyon testleri, LDH yüksekliği ve trombositopeni ile maternal komplikasyonlar arasında anlamlı ilişki olduğu saptanmıştır.

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Cite This Article

DEMİR, S. C., CANDAN, E., EVRÜKE, C., ÖZGÜNEN, F. T., ÜRÜNSAK, İ. F., KADAYIFÇI, O. (2004). The factors affecting morbidity and mortality in severe preeclampsia and HELLP syndrome cases. Medical Network Klinik Bilimler ve Doktor, Cilt: 10 - Sayı: 1, 96–100. https://ajindex.com/articles/279139

References (1)

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