Journals / Medical Network Klinik Bilimler ve Doktor / 1999 / Cilt: 5 - Sayı: 4

A non-Hodgkin lymphoma developing after phenytoin therapy

Phenytoin alımına bağlı olarak gelişen bir non-Hodgkin lenfoma olgusu

Pages
470–472
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Immunohistochemistry studies showed that neoplastic cells expressed Beta Antigens (CD20, lambda ).- 6 course of chemotherapy were done.

📌 3 Key Takeaways

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Objective & Hypothesis:We report non-Hodgkin lymphoma occuring 2 years after continous phenytoin therapy.
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Key Findings & Data:Despite withdrawal of phenytoin before 5 months, there was persistance of lymphadenopaty.
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Conclusion & Impact:Immunohistochemistry studies showed that neoplastic cells expressed Beta Antigens (CD20, lambda ).- 6 course of chemotherapy were done.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Antijenler · CD20 · Lenfom

Abstract

We report non-Hodgkin lymphoma occuring 2 years after continous phenytoin therapy. Despite withdrawal of phenytoin before 5 months, there was persistance of lymphadenopaty. Lymph node biopsy showed diffüz, small cleaved cell non-Hodgkin lymphoma. Immunohistochemistry studies showed that neoplastic cells expressed Beta Antigens (CD20, lambda ).- 6 course of chemotherapy were done.

Özet

Bu çalışmada, iki yıl sürekli olarak phenytoin kullanımına bağlı olarak geliştiği düşünülen bir non-Hodgkin lenfoma vakası sunuldu. Phenytoin kullanmayı 5 ay önce bırakmasına rağmen hastanın lenfadenopatileri mevcutlu. Lenfnodu biopsi sonucu diffüz küçük çentikli hücreli non-Hodgkin lenfoma (small cleaved cell non-Hodgkin lenfoma) olarak bulundu. İmmunohistokimyasal çalışmalar neoplastik hücrelerin Beta Antijeni (CD20 ve lambda) ihtiva ettiğini gösterdi. Hastaya 6 kür kemoterapi uygulandı.

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Cite This Article

GÖZÜ, I. H., TERZİOĞLU, N., MAVİŞ, O., ÖZGÜR, R., EKİZOĞLU, İ., ŞENKAL, Ö. (1999). A non-Hodgkin lymphoma developing after phenytoin therapy. Medical Network Klinik Bilimler ve Doktor, Cilt: 5 - Sayı: 4, 470–472. https://ajindex.com/articles/278926