Journals / Medical Network Klinik Bilimler ve Doktor / 2000 / Cilt: 6 - Sayı: 3

The relationship between the severity of preeclampsia and plasma lipoprotein (a) levels

Preeklampsinin şiddeti ile lipoprotein (a) seviyesi arasındaki ilişki

Pages
388–391
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

CONCLUSION: In this study, lipoprotein (a) levels was found to be higher in women with preeclampsia and there was a correlation between lipoprotein (a) levels and severity of preeclampsia.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVES: Our purpose is to evaluate the relation between the plasma levels of lipoprotein (a) and mild to severe preeclampsia.
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Key Findings & Data:MATERIAL AND METHOD: Lipoprotein (a) level was measured in 30 women with preeclampsia and in 30 normal pregnant women who were studied as control group.
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Conclusion & Impact:CONCLUSION: In this study, lipoprotein (a) levels was found to be higher in women with preeclampsia and there was a correlation between lipoprotein (a) levels and severity of preeclampsia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Preeklampsi · İleriye dönük çalışma · Ateroskleroz

Abstract

OBJECTIVES: Our purpose is to evaluate the relation between the plasma levels of lipoprotein (a) and mild to severe preeclampsia. MATERIAL AND METHOD: Lipoprotein (a) level was measured in 30 women with preeclampsia and in 30 normal pregnant women who were studied as control group. From 30 preeclamptic women, 15 of them were classified as mild and the other 15 as severe preeclampsia. RESULTS: Plasma lipoprotein (a) levels were found to be 10050 mg/L in normal pregnant women, 33060 mg/L in the group of mild preeclampsia and 650240 mg/L in women with severe preeclampsia. There was statistically important difference between the group with precclampsia and the control group in terms of lipoprotein (a) levels (p<0.05). also statistically important. difference was found between groups with mild and severe preeclampsia (z-4,295, p<0.05): None of lipoprotein (a) level was found to be higher than 300 mg/L in normal pregnant women. CONCLUSION: In this study, lipoprotein (a) levels was found to be higher in women with preeclampsia and there was a correlation between lipoprotein (a) levels and severity of preeclampsia.

Özet

AMAÇ: Kandaki lipoprotein (a) seviyeleri ile hafif ve şiddetli preeklampsi arasındaki ilişki araştırıldı. GEREÇ VE YÖNTEM: 01:10.1998 ile 30.01.1999 tarihleri arasında 30 preeklamptik 30 kontrol grubu hastada prospektif olarak lipoprotein (a) seviyeler} araştırıldı. 30 preeklamptik gebenin 15'i ağır 15'i hafif preeklampsi olarak gruplandırıldı. BULGULAR: Plazma lipoprotein (a) normal gebelerde 10050 mg/L, hafif preeklampside 33060 mg/L, ağır preeklampside 650240 mg/L olarak tespit edildi. Lipoprotein (a) yönünden kontrol grubu ile preeklamptik grup arasında istatistiksel olarak anlamlı fark görüldü (p<0.05). yine lipoprotein (a) seviyesi bakımından hafif preeklampsi ile ağır preeklampsi arasında istatistiksel olarak anlamlı bir fark tespit edildi (z-4,295, p<0.05). normal gebelerin hiç birinde lipoprotein (a) seviyesi 300 mg/L üzerinde saptanmadı. SONUÇLAR: Yapılan bu çalışmada lipoprotein (a) 'nın preeklamptik gebelerde yükseldiği ve preeklampsinin ağırlığı ile lipoprotein (a) arasında bir ilişki olduğu saptandı.

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Cite This Article

ÇELİK, Ç., ACAR, A., ALBENİ, H., ÇAPAR, M., GÖRKEMLİ, H., VATANSEV, H., AKYÜREK, C. (2000). The relationship between the severity of preeclampsia and plasma lipoprotein (a) levels. Medical Network Klinik Bilimler ve Doktor, Cilt: 6 - Sayı: 3, 388–391. https://ajindex.com/articles/278895

References (9)

  1. Toppozada MK, Darwish E Barakat AZT: Manegement of preeclampsia detected in early labor by prostaglandin Al or dhyralazine infusions American J. Obstret Gynocol 1991; 164:1229-1232
  2. Şen C, Madazli R, Ocak V: Gebelikte hipertansiyon/tanim ve siniflama. Perianatoloji Dergisi; 1993; 1:7-10
  3. Mac Gillivray I: Preeclampsia: The hipertensive disease of pregnancy. WB Sounders, Philadelphia; 1983:17
  4. Valeria J. Rapport, MD; Greigh Hirata MD, Hui Kim Yap, MD and Stanley C. Jordan MD: Antivasculer endothelial cell antibadie? Severe preeclampsia. Los Angeles California, 162, (1), 138
  5. Robert N Taylor, Md, Ph. Cristianna J. M., de Groot, MD, Ph, D., Yong K. Cho, MD "Circulating Factors as Markers and Mediators of Endothelial Cell Dysfunction in Preeclampsia" Seminars in Reproductive Endocrinology; 1998; 16: 1,22
  6. Scanu AM, Scantrani L. Lipoprotein (a); Structure Biology and Clinical relevance Adu Intern Med; 1991; 36:249
  7. Scott J. Thrombogenezis linked to atherogenesis at least Nature; 1989; 341:22-3
  8. Dahlen GH. Lipoprotein (a): Lipoprotein in cardiovasküler disease. Science; 1994; 108:111-26
  9. Hegele RA: Lipoprotein (a): An emergingrisk faktör for atherosklerosis Can J Cardiol, 1989; 5:263. 10.Houlsan R, Frield W: Biochemistry and clinical significance of lipoprotein (a) Ann Clin Biochem; 1988; 25:499. 11.Dahlen G Guyton JR, Attor M: Association of levels, plasma lipids and other lipoprotein with coronary artru disease documented by angiography. Circulation; 1986; 74:758-65. 12.Robertson WB Brosens I, Dixon G. The Pathological response of the vessels of the vessels of the placental bed to hipertensive disorders of pregnancy J. Path Bact 1967; 93: 581-93.15 La Rosa JC: Cholesterol lowering, low Cholesterol and Mortality. Am. J. Cardiology 1993; 72:776-786. 13.Kumar Cotton MD, Stanley L. Robbins, MD, Basic Patoloji (Temel patoloji), Philadelphia, London, Toronto, Montreal, Sydney, Tokyo, Çev: Prof. Dr. Uğur Çevikbaş, 1994:280-382. 14.James M. Roberts, MD, PhD, Thomas J. Musci, MD, George M. Rodgers, MD, PhD, Carl A. Hubel, PhD and Margaret K. McLaughlin, PhD "Preeclampsia: An endothelial cell disorder" American J. Obstet. Gynocol 1989; 101; 5:1202-1203. 15.Jian Wang, PhD, Shigeko Mimuro, MB, BS, Robert Lahoud, MB. BS, Brian Trudinger, MD and Xing Li Wang, PhD "Elevated levels oflipoprotein (a) in women with preeclampsia" Am J Obstet Gynecol, Jaunary 1998: 178. 1, 1-148. 16.Williams KJ: Tabas The response to retention hypothesis of early atherog