Journals / Medical Network Klinik Bilimler ve Doktor / 2001 / Cilt: 7 - Sayı: 4

Hematological changes in brucellosis

Brusellozda hematolojik değişiklikler

Pages
441–443
DOI
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⚡ TL;DR(Too Long; Didn't Read)

CONCLUSION: Although the most frequent reported hematologic abnormalitiy in brucellosis is anemia, we found normal leucocyte count with relative lymphomonocytosis in our patients.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: Brucellosis is a systemic infection that can involve many organs and tissue.
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Key Findings & Data:MATERIAL AND METHODS: Haematological findings of 120 adult brucellosis cases which was diagnosed at the Infectious Disease Department of Gaziantep University School of Medicine were evaluated retrospectively.
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Conclusion & Impact:CONCLUSION: Although the most frequent reported hematologic abnormalitiy in brucellosis is anemia, we found normal leucocyte count with relative lymphomonocytosis in our patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Lökosit sayımı · Lökosit bozuklukları · Geriyedönük çalışma

Abstract

AIM: Brucellosis is a systemic infection that can involve many organs and tissue. It is an endemic disease in the around Gaziantep. Many different haematological abnormalities have been reported during course of brucellosis in adults. Because of isolation of the causative agent is difficult and time consuming, other laboratory findings may be required for the diagnosis of brucellosis. MATERIAL AND METHODS: Haematological findings of 120 adult brucellosis cases which was diagnosed at the Infectious Disease Department of Gaziantep University School of Medicine were evaluated retrospectively. RESULTS: We found normal leukocyte count in 94(78.3%), leukopenia in 10(8.3%), leukocytosis in 8(6.6%), pancytopenia in 8(6.6%), and thrombocytopenia in 4(3.3%), anemia in 44(36.6%) patients. All of leucopenic and pancytopenic cases were neutropenic. Relative lymphomonocytosis was found in 86(71.6%) patients. While erythrocte sedimentation rate(ESR) was normal in 54(45.0%) cases, it was elevated in 66(55.5%) patients. CONCLUSION: Although the most frequent reported hematologic abnormalitiy in brucellosis is anemia, we found normal leucocyte count with relative lymphomonocytosis in our patients.

Özet

AMAÇ: Gaziantep ve çevresinde endemik bir hastalık olan bruselloz, bir çok doku ve organların tutulabildiği sistemik bir infeksiyon hastalığıdır. İnfeksiyonun seyri sırasında çok farklı hematolojik bulgular tanımlanmıştır. Etken izolasyonunun zor ve zaman alıcı olmasından dolayı tanıda diğer laboratuar bulgularına sıklıkla ihtiyaç duyulur. GEREÇ VE YÖNTEM: Bu amaçla, Gaziantep Üniversitesi Tıp Fakültesi İnfeksiyon Hastalıkları ve Klinik Bakteriyoloji Anabilim Dalında bruselloz tanısı konulmuş 120 erişkin olgunun hematolojik bulgularını retrospektif olarak irdeledik. Olguların 72'si kadın, 44'ü erkekti. BULGULAR: 94(%78.3) olgunun lökosit sayısı normal iken, on(%8.3) olguda lökopeni, sekiz(%6.6) olguda lökositoz, sekiz(%6.6) olguda pansitopeni ve dört(%3.3) olguda ise trombositopeni saptandı. 120 olgunun 44(%36.6)'ünde ise anemi tespit edildi. Lökopenili ve pensitopenili olguların hepsinde nötropeni mevcuttu. Olguların 86(%71.66)'sında rölatif lenfomonositoz tesbit edildi. Eritrosit sedimentasyon hızı 54(%45.0) olguda normal sınırlarda iken, 66(%55.5) olguda normalden yüksek bulundu. SONUÇ: Bu konuda yapılan çalışmalarda genellikle pansitopeni ya da sadece anemi saptanmasına karşın bu çalışmada olgularda en sık görülen hematolojik bulgu normal lökosit sayısı ile beraber rölatif lenfomonositozdur.

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Cite This Article

NAMIDURU, M., KARAOĞLAN, İ., BAYEZİT, N. (2001). Hematological changes in brucellosis. Medical Network Klinik Bilimler ve Doktor, Cilt: 7 - Sayı: 4, 441–443. https://ajindex.com/articles/278829

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