Journals / Medical Network Klinik Bilimler ve Doktor / 2000 / Cilt: 6 - Sayı: 3

Hypernatremia with thrombocytopenia: Is hypernatremia a cause of thrombocytopenia?

Trombositopeni ile birlikte hipernatremi: Hipernatremi trombositopeninin bir nedeni mi?

Pages
305–307
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case report is the first case report about thrombocytopenia with hypernatremia.

📌 3 Key Takeaways

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Objective & Hypothesis:Thrombocytes arise from the fragmentation of megakaryocytes, which are polypoid bone marrow cells and after leaving the bone marrow, two-thirds circulate for 7 to 10 days, while one-thirds are sequestered in the spleen.
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Key Findings & Data:Only a small fraction of the thrombocytes is consumed in the process of hemostasis, so most thrombocytes are removed by phagocytic cells, the normal blood thrombocytes count is maintaned between 150.000 and 450.000 per microliter.
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Conclusion & Impact:This case report is the first case report about thrombocytopenia with hypernatremia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Megakaryositler · Tanı teknik ve işlemleri · Kan trombositleri

Abstract

Thrombocytes arise from the fragmentation of megakaryocytes, which are polypoid bone marrow cells and after leaving the bone marrow, two-thirds circulate for 7 to 10 days, while one-thirds are sequestered in the spleen. Only a small fraction of the thrombocytes is consumed in the process of hemostasis, so most thrombocytes are removed by phagocytic cells, the normal blood thrombocytes count is maintaned between 150.000 and 450.000 per microliter. Hypernatremia (serum sodium level of > 145 mEq/L) is associated with high mortality especially in the elderly population. We here presented a 70 - year - old man with thrombocytopenia 5000/mL associated with hypernatremia (182 mEq/L). This case report is the first case report about thrombocytopenia with hypernatremia.

Özet

Trombositler polipoid kemik iliği hücreleri olan megakary asitlerin fragmantasyonu sonucunda oluşur ve kemik iliğini terkettikten sonra üçte biri dalakta sekestrasyona uğrarken üçte ikisi 7-10 gün dolaşımda kalır. Çok az bir kısmı hemostazda kullanılır, çoğunluğu fagositik hücreler tarafından yok edilir. Normal kan platelet sayısı 150.000- 450.000/mm3 arasındadır.. Hipernatremi (serum sodyum seviyesi > 145 mEq/L) özellikle yaşlı popülasyonda yüksek mortalite ile ilişkilidir. Burada 70 yaşında hipernatremi (182 mEq/L) ve trombositopenisi (5000/mm3) olan bir olgu sunulmuştur. Bu olgu sunumu literatürdeki ilk hipernatremi ile birlikte trombositopeni olgusudur.

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Cite This Article

GÖKEL, Y., GÜVENÇ, B., DURU, M. (2000). Hypernatremia with thrombocytopenia: Is hypernatremia a cause of thrombocytopenia?. Medical Network Klinik Bilimler ve Doktor, Cilt: 6 - Sayı: 3, 305–307. https://ajindex.com/articles/278770

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