SavedAdd your journal

Journals / Medical Network Klinik Bilimler ve Doktor / 2001 / Cilt: 7 - Sayı: 1

Serum total antioxidant levels in patients with preeclampsia

Preeklampside total serum antioksidan seviyeleri

Tayfun GÜNGÖR
Duygu ARIBAŞ
Emel Ebru PARLAKYİĞİT
Fazlı DEMİRTÜRK
Oya GÖKMEN
Pages
95–97
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Also, the total antioxidant levels of the severe preeclamptic patients were found be significantly lower than the mild preeclamptic patients (p<0.001),

📌 3 Key Takeaways

🎯
Objective & Hypothesis:OBJECTIVE: To explain the ethiology of preeclampsia, total antioxidants' levels were studied.
📊
Key Findings & Data:MATERIAL AND METHODS: We measured the total antioxidant levels of 50 preeclamptic patients and compared the results with the total antioxidant levels of 30 normal pregnants in order to clarify the indefinite ethiology of the preeclampsia.
💡
Conclusion & Impact:Also, the total antioxidant levels of the severe preeclamptic patients were found be significantly lower than the mild preeclamptic patients (p<0.001),
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Gebelik · Antioksidanlar · Beslenme durumu

Abstract

OBJECTIVE: To explain the ethiology of preeclampsia, total antioxidants' levels were studied. MATERIAL AND METHODS: We measured the total antioxidant levels of 50 preeclamptic patients and compared the results with the total antioxidant levels of 30 normal pregnants in order to clarify the indefinite ethiology of the preeclampsia. RESULTS: Social-economic levels and nutricious habits of the patients were similar. Total antioxidant levels of the preeclamptic patients were similar. Total antioxidant levels of the preeclamptic patients were found to be significantly lower than the control group (p<0.001. CONCLUSION: Total antioxidant levels were found as 1.101±0.080, 1.030±0.207 and 0.860±0.172 respectively in normal pregnants, mild preeclamptic pregnants and severe preeclamptic pregnants. Also, the total antioxidant levels of the severe preeclamptic patients were found be significantly lower than the mild preeclamptic patients (p<0.001),

Özet

AMAÇ: Preeklampsi etiyolojisinde belirsizliği aydınlatmaya yönelik olarak preeklamptik gebelerde total antioksidan düzeylerini araştırmaktadır. GEREÇ VE YÖNTEM: Total antioksidan düzeyleri ölçülen 50 hasta, normal gebelikleri bulunan 30 hasta ile karşılaştırıldı. BULGULAR: Olguların sosyoekonomik ve beslenme alışkanlıkları benzerdi. Preeklamptik hastalarda total antioksidan düzeyleri kontrol grubuna göre belirgin olarak azalmış bulundu (p<0,001). SONUÇ: Normal gebelerde, hafif preeklamptik gebelerde ve ağır preeklamptik gebelerde total antioksidan düzeyleri sırasıyla 1.01±0.080, 1.030±0.207 ve 0.860±0.172 olarak bulunmuştur. Ayrıca ağır preeklamptik gruptaki hastaların total antioksidan düzeyleri de hafif preeklamptik gruptakilerden belirgin olarak düşük bulunmuştur (p<0.001).

🔖

Cite This Article

GÜNGÖR, T., ARIBAŞ, D., PARLAKYİĞİT, E. E., DEMİRTÜRK, F., GÖKMEN, O. (2001). Serum total antioxidant levels in patients with preeclampsia. Medical Network Klinik Bilimler ve Doktor, Cilt: 7 - Sayı: 1, 95–97. https://ajindex.com/articles/278716

References (11)

  1. Cunningham F.G., Lindheimer: Hypertension in pregnancy; current concepts. N.Engl.J.Med.1992: 326; 927-32
  2. Hubel G.A., Roberts J.M: Lipid peroxidation in pregnancy: New perspectives on preeclampsia. Am J Obst Gynecol 1989: 1061; 1025-34
  3. Rodgers G.M., Taylor R.N: Preeclampsia with a serum actor cytotoxic to human endothelial cells. Am J Obst Gynecol 1988: 159; 908-14 Pryor W.A.: Free radical biology: xenobiotics, cancer and aging. Ann NY Acad Sci 1982: 82; 1-22
  4. Wisoom S.J., Wilson R.: Antioxidant systems innormal pregnancy and pregnancy induced hypertension. Am J Obst Gynecol 1991:165; 1701-4
  5. Yuping W., Scott W.: Th imbalance between thromboxane and prostacyclin in preeclampsia is associated with an imbalance between lipid peroxides and vitamine E in maternal blood. Am J Obst Gynecol 1991:165;1695-1700. Kagan V.E.: Tocopherol stabilizes membrane against phospholipase A, free fatty acids. Ann NY Acad Sci 1989:570;121-35.
  6. Mead J.F., Alfin R.B.: Peroxidation of fatty acids: Lipids, chemistry, biochemistry and nutrition. New York: Plenum Press 1986:83-89
  7. Maseki M., Nishigaki I.: Lipid peroxide level and lipid serum content of serum lipoprotein fractions of pregnant subjects with and without preeclampsia. Clin Chem Acta 1981:155;155-161
  8. Davidge S.T., Hubel G.A.: Sera antioxidant activity in uncomplicated and preeclamptic pregnancies. Obstet Gynecol 1992:79;897-901
  9. Mikhail S.M., Akolisa A.: Preeclampsia and antioxidant nutrients; decreased plasma levels of reduced ascorbic acid, a-tocopherol and b-carotene in women with preeclampsia. Am J Obst Gynecol 1994:171;150-7 The American Collage of Obstetricians and Gynecologists: Management of preeclampsia. Washington D.C.: The American Collage of Obstetricians and Gynecologists 1986 (Technical bulletin no:91) Jendryczko A., Drozdz M.: Plasma retinol, b-carotene and vitamine E levels in relatin to the future risk of preeclamhsia. Zentabl Gynecol 1989:111;1121- 3 Diplock A.: Antioxidant nutrients and disease prevention; an overview. Am J ClinNutrl991:53;189-93
  10. Roberts J.M., Roberts N. T.: Preeclampsia: an endothelial cell disorder. Am J Obst Gynecol 1989: 161;1200-4
  11. Roberts J.M., Taylor R.M.: Clinical and biochemical evidence of endothelial cell dysfunction in the pregnancy syndrome preeclampsia. Am J Hypertension 1991:4;700-8