SavedAdd your journal

Journals / Medical Network Klinik Bilimler ve Doktor / 2004 / Cilt: 10 - Sayı: 2

A retrospective study of the relation between eradication therapy for esophageal varices and occurence and severity of fundal varices

Özofagus varis eradikasyon tedavisinin fundal varis oluşumu ve şiddetlenmesi ile ilişkisi; retroskopik çalışma

EMİN ALTIPARMAK
Mehmet ARHAN
Seyfettin KÖKLÜ
Ö. Faruk YOLCU
İbrahim ERTUĞRUL
Osman YÜKSEL
Pages
140–142
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: After eradication of esophageal varices by band ligation, fundal varices and portal hypertensive gastropathy occur with increased incidence.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: After variceal eradication, the hemodynamics of the portal system undergoes changes.
📊
Key Findings & Data:Materials and Methods: Records of 89 patients undergoing eradication therapy in our clinic between 1996 and 2003 were examined and data on fundal varices and portal hypertensive gasropathy before and after eradication were compared.
💡
Conclusion & Impact:Conclusion: After eradication of esophageal varices by band ligation, fundal varices and portal hypertensive gastropathy occur with increased incidence.
🔬Design:Research Article
📍Scope:2003 Verileri
⚙️Variables:Görülme sıklığı · Geriyedönük çalışma · Özofageal ve gastrik varisler

Abstract

Objective: After variceal eradication, the hemodynamics of the portal system undergoes changes. The aim of this sudy is to evaluate the effects of eradication therapy on the occurence and severity of fundal varices and portal hypertensive gastropathy. Materials and Methods: Records of 89 patients undergoing eradication therapy in our clinic between 1996 and 2003 were examined and data on fundal varices and portal hypertensive gasropathy before and after eradication were compared. For statistical analysis the Mc. Nemar test was performed. Results: Before eradication, 39 patients (43.8%) had fundal varices, compared to 47 patients (52.8%) who had fundal varices after eradication (P<0.05). Before eradication, 60 patients (67.4%) had portal hypertensive gastropathy, while 74 patients (83.1%) had portal hypertensive gastropathy after eradication (P<0.05). Conclusion: After eradication of esophageal varices by band ligation, fundal varices and portal hypertensive gastropathy occur with increased incidence.

Özet

Amaç: Özofagus varis eradikasyonu sonrasında portal sistemde hemodinamik bazı değişiklikler oluşmaktadır. Bu çalışmada eradikasyonun fundal varis ve portal hipertansif gastropati oluşumu ve şiddetlenmesi üzerindeki etkilerini değerlendirmeyi amaçladık. Gereç ve Yöntem: 1996-2003 yılları arasında kliniğimizce özofagus varis eradikasyon programına alınmış olan hastaların kayıtları retrospektif olarak incelendi ve varisleri eradike olan 89 hastanın eradikasyon öncesi ve sonrası fundal varis ve portal hipertansif gastropati verileri karşılaştırıldı. İstatistik değerlendirme için McNemar testi kullanıldı. Bulgular: Hastaların eradikasyon öncesinde 39 (%43.8)'unda fundal varis varken eradikasyon sonrasında 47 (%52.8)'sinde fundal varis vardı (p<0.05). Eradikasyon öncesinde 60 (%67.4) hastada portal hipertansif gastropati varken eradikasyon sonrası 74 (%83.1) hastada portal hipertansif gastropati vardı (p<0.05). Sonuç: Özofagus varislerinin endoskopik band ligasyonu ile eradikasyonu sonrasında fundal varis ve portal hipertansif gastropati insidansda artış olmaktadır.

🔖

Cite This Article

ALTIPARMAK, E., ARHAN, M., KÖKLÜ, S., YOLCU, Ö. F., ERTUĞRUL, İ., YÜKSEL, O. (2004). A retrospective study of the relation between eradication therapy for esophageal varices and occurence and severity of fundal varices. Medical Network Klinik Bilimler ve Doktor, Cilt: 10 - Sayı: 2, 140–142. https://ajindex.com/articles/278490

References (14)

  1. Lo GH, Lai KH, Cheng JS, et al." A prospective, randomized trail of sclerotherapy versus ligation in the management of bleeding esophageal varices. Hepatology 1995; 22:466-71.
  2. Pena J, Rivero M, Sanchez E, et al. Variseal ligation compared with endoscopic sclerotherapy for variceal hemorrhage: pective randomized trail. Gastrointest Endosc 1999; 49:417-23.
  3. Hou MC, Lin HC, Chen CH, et al. Changes in portal Intensive gastropathy after endoscopic variceal sclerotherapy gation: an endoscopic observation. Gastrointest Endosc 42:139-44.
  4. Tayama C, Iwao T, Oho K, et al. Effect of large fundal varices on changes in gastric mucosal hemodynamics endoscopic variceal ligation. Endoscopy 1998; 30:25-31.
  5. McCormack TT, Sims J, Eyre-Brook I, et al. Gastric lesions in portal hypertension: Inflammatory gastritis or conge gastropathy? Gut 1985; 26:1226-32.
  6. Quintero E, Pique JM, Bombi JA, et al. Gastric mucosal vascular ectasia causing bleeding in cirrhosis: A distinct entity associated with hypergastrinemia and low serum levels of pepsinogen 1. Gastroenterology 1987; 93:1054-61.
  7. Panes J, Bordas JM, Pique JM, et al. Increased gastric mucosal perfusion in cirrhotics with portal hyperte gastropathy. Gastroenterology 1992; 103:1875-82.
  8. Ohta M, Hashizume H, Higashi H, et al. Portal and gastric mucosal hemodynamics in cirrhotic patients with portal hypertensive gastropathy. Hepatology 1994; 20:1432-6.
  9. Iwao T, Toyonaga A, Ikegami M, et al. Reduced gastric mucosal blood flow in patients with portal-hypertensive gastropathy. Hepatology 1993; 18:36-40.
  10. Nishiwaki H, Asai T, Sowa M, et al. Endoscopic measurement of gastric mucosal blood flow with special reference to the effect of sclerotherapy in patients with cirrhosis. Am J Gastroenterol 1990; 85:34-7.
  11. Shiv KS, Anwrag G, Ajay KJ, et al. Prospective randomized trail of endoscopic sclerotherapy versus variceal band ligation for esophageal variecs: influence on gastropathy, gastric varices and variceal recurrence. Journal of Hepatology 1997; 26:826-32.
  12. Sarin SK, Bhatia V. To ligate or to sclerose: beginning new era in the management of esophageal varices? Hepatology 1993; 15:746-8.
  13. Iwao T, Toyonaga A, Oho K, et al. Portal-hypertensive gastropathy develops less in cirrhotic patients with fnudal varices. J Hepatol 1997; 26:1235-41.
  14. Ichiro Y, MD, Ph.D, Ikuo Murata, et al. Effects of endoscopic variceal ligation on portal hipertensive gastropathy and geastric mukosal blood flow. AJG 1998; 93:71 -4. Watanabe K, Kimura K, Matsutani S, et al. Por