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Journals / Medical Network Klinik Bilimler ve Doktor / 2004 / Cilt: 10 - Sayı: 5

Clinical and laboratory characteristics of typhoid fever in children

Çocuklarda tifonun klinik ve laboratuar özellikleri

Saadet AKARSU
Metin Kaya GÜRGÖZE
MEHMET KILIÇ
Erdal TAŞKIN
Erdal YILMAZ
Oya ÇAKICI
A. Denizmen AYGÜN
Pages
544–551
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The clinical and laboratory properties of typhoid fever in children were determined.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Enteric fever is produced by Salmonella (S) typhi, S. paratyphi A, B and C.
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Key Findings & Data:Material and Method: This was a retrospective study of 31 confirmed cases.
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Conclusion & Impact:Conclusion: The clinical and laboratory properties of typhoid fever in children were determined.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Çocuk · Geriyedönük çalışma · Salmonella typhi

Abstract

Objective: Enteric fever is produced by Salmonella (S) typhi, S. paratyphi A, B and C. Typhoid fever is a systemic infectious disease caused by S. typhi. This eight-year study was carried out to evaluate the clinical and laboratory properties of typhoid fever and the density in children. Material and Method: This was a retrospective study of 31 confirmed cases. The laboratory diagnosis of typhoid fever was dependent upon either the isolation of S. typhi from a clinical sample or the detection of raised titers of agglutinating serum antibodies against the lipopolysaccharide or flagellum antigens of serotype typhi (the Widal test). The most common complaints were fever (32%), and headache (23%). The most common clinical finding was splenomegaly (19%). Result: Culture was positive in 26% of the cases with a final clinical diagnosis of typhoid fever. Anemia was present in 13%, leukopenia in 32%, neutropenia in 16%, and trombocytopenia in 26% in of the cases. Conclusion: The clinical and laboratory properties of typhoid fever in children were determined.

Özet

Amaç: Ateşli barsak hastalığı Salmonella (S) typhi, S. paratyphi A, B ve C ile gelişir. Tifo, S. Typhi'nin etken olduğu sistemik bir infeksiyöz hastalıktır. Bu sekiz yıllık çalışma; tifonun klinik ve laboratuar özelliklerini ve çocuklardaki sıklığını değerlendirmek için yapıldı. Gereç ve Yöntem: Bu 31 doğrulanmış olgunun retrospektif çalışmasıdır. Tifonun laboratuar tanısı ya klinik bir örnekten S. typhi izolasyonu ya da lipopolisakkarit ya da kirpik antijenlerine karşı aglütinasyon yapan serum antikorlarının yüksek titrasyonlarına (Widal testi) bağlıydı. En yaygın görülen şikayetler ateş (%32) ve baş ağrısı (%23) oldu. En yaygın klinik özelliği splenomegali (%19) oldu. Bulgular: Kültür son klinik tanısı tifo olan olguların %26'sında pozitif bulundu. Anemi hastaların %13, lökopeni %32, nötropeni %16 ve trombositopeni %26'sında görüldü. Sonuç: Çocuklarda tifonun klinik ve laboratuar özellikleri saptandı.

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Cite This Article

AKARSU, S., GÜRGÖZE, M. K., KILIÇ, M., TAŞKIN, E., YILMAZ, E., ÇAKICI, O., AYGÜN, A. D. (2004). Clinical and laboratory characteristics of typhoid fever in children. Medical Network Klinik Bilimler ve Doktor, Cilt: 10 - Sayı: 5, 544–551. https://ajindex.com/articles/278487

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