SavedAdd your journal

Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2006 / Cilt: 12 - Sayı: 1

The diagnostic value of lactate dehydrogenase (LDH) and LDH isoenzymes in recurrent extertional rhabdomyolysis in two horses

Tekrarlayan rabdomiyoliz olgusu gözlenen iki atta, laktat dehidrogenaz

Aziz Arda SANCAK
Duygu ÇAKIROĞLU
Pages
73–76
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As the activity of these enzymes peaks in 24 hours and remains stabil for a considerable period, determination of their levels may be beneficial in the diagnosis of subclinical and clinical rhabdomyolysis episodes.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Recurrent exertional rhabdomyolysis is an important problem of race horses all over the world.
📊
Key Findings & Data:This case report demonstrates the diagnostic value of LDH and 4. and 5.
💡
Conclusion & Impact:As the activity of these enzymes peaks in 24 hours and remains stabil for a considerable period, determination of their levels may be beneficial in the diagnosis of subclinical and clinical rhabdomyolysis episodes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:rabdomiyoliz · olgu sunumları · klinik görünüm

Abstract

Recurrent exertional rhabdomyolysis is an important problem of race horses all over the world. This case report demonstrates the diagnostic value of LDH and 4. and 5. LDH isoenzymes in recurrent exertional rhabdomyolysis in two horses. As the activity of these enzymes peaks in 24 hours and remains stabil for a considerable period, determination of their levels may be beneficial in the diagnosis of subclinical and clinical rhabdomyolysis episodes.

Özet

Tekrarlayan egzersize bağlı rabdomiyoliz, tüm dünyada yarış atlarının önemli bir hastalığıdır. Bu iki olgu, iki atta, tekrarlayan egzersize bağlı rabdomiyolizde LDH ve 4 ve 5. LDH izoenzimlerinin diagnostik önemini ortaya koymaktadır. Bu izoenzimlerin aktivitesi 24 saatte pik noktaya ulaşıp, önemli bir süre stabil kaldığından, ölçümleri subklinik rabdomiyoliz ve rabdomiyoliz nöbetlerinin teşhisinde yararlı olabilir

🔖

Cite This Article

SANCAK, A. A., ÇAKIROĞLU, D. (2006). The diagnostic value of lactate dehydrogenase (LDH) and LDH isoenzymes in recurrent extertional rhabdomyolysis in two horses. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 12 - Sayı: 1, 73–76. https://ajindex.com/articles/274194

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. 1 Collinder E, Lindholm A, Rasmusoıı M: Genetic markers in Standardbred trotters susceptible to the rhabdomyolysis syndrome. Eq Vet J, 29(2): 117-120, 1997. 2 Lentz LR, Valberg SJ, Balog EM, Mickelson JR, Gallant EM: Abnormal regulation of muscle contraction in horses with recurrent exertional rhabdomyolysis. Am J Vet Res, 60(8): 992-999, 1999. 3 McGowan CM, Fordham T, Christley RM: Incidence and risk factors for exertional rhabdomyolysis in thoroughbred racehorses in the United Kingdom. The Veterinary Record, 151,623-626,2002. 4 McGowan CM, Menzies-Gow N.I, McDiarmid AM, Patterson-Kane JC: Four cases of equine polysaccharide storage myopathy in the United Kingdom. The Veterinary Record, 152, 109-112. 2003. 5 MacLeay.1, Valberg SJ, Pagan.11), Xue JL, DeLaCorte FD, Roberts J: Effect of ration and exercise on plasma creatine kinase acticity and lactate concentration in Thoroughbred horses with recurrent exertional rhabdomyolysis. AJVR, 61(11): 1390-1395,2000. 6 McKenzie EC, Valberg SJ. Godden S.VI, Pagan JD, Carlson GP, MacLeay JM, DeLaCorte F: Plasma and urine electrolyte and mineral concentrations in Thoroughbred horses with recurrent exertional rhabdomyolysis after consumption of diets varying in cation-anion balance. AJVR, 63(7): 1053-1061,2002. 7 Harris PA: An outbreak of the equine rhabdomyolysis syndrome in a racing yard. The Veterinary Record. 10. 468-470, 1990. 8 Scholtc HR, Verduin MHM, Ross JD, VanDcrHoven R, Wensing T, Breuking IIJ, Mcijer AEFII: Short Communication; Equine exertional rhabdomyolysis: activity of the mitochondrial respiratory chain and the carnitine system in skeletal muscle. Eq Vet J. 23(2): 142-144, 1991. 9 Valberg S, Jönsson L, Lindholm A, Holmgren N: Muscle histopathology and plasma aspartate aminotransferase, creatine kinase and myoglobin changes with exercise in horses with recurrent exertional rhabdomyolysis. Eq Vet J. 25( 1): 11-16. 1993. 10 Chiaradia E, Avellini L, Rueca F, Spaterna A, Porciello F, Antonioni MT, Gaiti A: Physical exercise, oxidative stress and muscle damage in racehorses. Comparative Biochemistry and Physiology Pari B: Biochemistry and Molecular Biology. U9(4):~833-8~36, 1988. 11 Washizu T, Nakamura M, Izawa N, Suzuki E, Tsuruno S, Washizu M, N'akıı.jo S, Arai T: The activity ratio of the cytosolic MDH/LDH and the isoenzyme pattern of LDH in the peripheral leukocytes of dogs, cats arid rabbits. Vet Res Com. 26.341-346.2002. 12 Turgut K: Veteriner Klinik Laboratuar Teşhis. Bahçıvanlar basım. Genişletilmi