Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2001 / Cilt: 7 - Sayı: 1

Reduced glutathione and malendialdehyde levels with catalase enzyme activity in the heart, skeletal muscle and liver of lambs with white muscle disease

Beyaz kas hastalıklı kuzuların kalp, iskelet kası ve karaciğerlerinde redükte glutatyon ve malondialdehit düzeyleri ile katalaz enzim aktivitesi

Pages
1–5
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Lipid peroxidation levels in the heart and skeletal muscles of affected lambs were significantly (p<0.01. p<0.001 ) increased although the increase in the liver was not significant (p>0.05).

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to determine lipid peroxidation (LPO) and reduced glutathione (GSH) levels and the activity of catalase enzyme (CAT: EC, 1.11.1.6) in the heart, skeletal muscles and liver of lambs with White Muscle Disease (WMD).
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Key Findings & Data:Fifeteen lambs with WMD and 15 healthy Morkaraman lambs were the subject of this study.
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Conclusion & Impact:Lipid peroxidation levels in the heart and skeletal muscles of affected lambs were significantly (p<0.01. p<0.001 ) increased although the increase in the liver was not significant (p>0.05).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:karaciğer · kuzu · kaslar

Abstract

The aim of this study was to determine lipid peroxidation (LPO) and reduced glutathione (GSH) levels and the activity of catalase enzyme (CAT: EC, 1.11.1.6) in the heart, skeletal muscles and liver of lambs with White Muscle Disease (WMD). Fifeteen lambs with WMD and 15 healthy Morkaraman lambs were the subject of this study. Reduced glutathione levels in the heart and skeletal muscles were significantly (p<0.001) reduced in affected lambs with the disease. The reduction in CAT enzyme activity was highly significant (p<0.001 ) in the skeletal muscles of affected lambs and significant (p<0.01) in the heart muscles. However, the reduction in the same parameters was not significant (p>0.05) in the liver. Lipid peroxidation levels in the heart and skeletal muscles of affected lambs were significantly (p<0.01. p<0.001 ) increased although the increase in the liver was not significant (p>0.05).

Özet

Bu çalışmada Beyaz Kas Hastalıklı (White Muscle Disease-WMD) kuzuların kalp ve iskelet kasları ile karaciğerlerinde lipid peroksidasyon (LPO) ve redükte glutatyon (GSH) düzeyleri ile katalaz (CAT: EC, 1.11.1.6) enzim aktivitesinin belirlenmesi amaçlandı. Çalışmada 15 hastalıklı ve 15 sağlıklı Morkaraman kuzu kullanıldı. Hastalıklı kuzuların kalp ve iskelet kaslarında GSH düzeylerinde önemli (p 0.05). Lipid peroksidasyon düzeyleri ise, hastalıklı kuzuların kalp ve iskelet kaslarında sırasıyla önemli (p 0.05).

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Cite This Article

BEYTUT, E., ERİŞİR, M., AKSAKAL, M. (2001). Reduced glutathione and malendialdehyde levels with catalase enzyme activity in the heart, skeletal muscle and liver of lambs with white muscle disease. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 7 - Sayı: 1, 1–5. https://ajindex.com/articles/274050

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