Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2011 / Cilt: 17 - Sayı: 2

Respiratorik distres sendromlu spontan premature buzağılarda koagulasyon profi linin değerlendirilmesi

The evaluation of coagulation profi les in spontaneous premature calves with respiratory distress syndrome

Pages
197–201
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Additionally, these findings may be of value in forming bases for future studies.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to determine coagulation profi les of spontaneous premature calves with respiratory distress syndrome.
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Key Findings & Data:The study involved spontaneous premature calves with respiratory distress syndrome (n= 20) and clinically healthy newborn calves (n= 10).
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Conclusion & Impact:Additionally, these findings may be of value in forming bases for future studies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:buzağı · koagulasyon testi · hematoloji

Abstract

The aim of this study was to determine coagulation profi les of spontaneous premature calves with respiratory distress syndrome. The study involved spontaneous premature calves with respiratory distress syndrome (n= 20) and clinically healthy newborn calves (n= 10). Blood samples were collected from all calves within the period between 2nd and 12th h of delivery to determine platelets (PLT), activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT), serum fibrin/fibrinogen degradation products (FDPs), and fibrinogen. Premature calves had prolonged APTT (P<0.001) and PT (P<0.01), decreased fibrinogen concentration (P<0.001) and decreased platelet counts (P<0.001) when compared to controls. An insignificant prolondation of TT was observed in 8 premature calves and two of which had also FDPs when compared to control calves. Abnormal, but insignifi cant fi ndings of FDPs were noted in six premature calves with respiratory distress syndrome when compared to healthy calves. As a result, premature calves with respiratory distress syndrome had abnormal coagulation profi le and seven of these died despite intensive therapy. The veterinarian should take these results in consideration when dealing with premature calves with respiratory distress syndrome and constitute an appropriate treatment. Additionally, these findings may be of value in forming bases for future studies.

Özet

Bu çalışma, respiratorik distres sendromlu spontan premature buzağılarda koagülasyon profilini belirlemek amacıyla yapıldı. Bu çalışmada, respiratorik distres sendromlu spontan premature (n=20) ve klinik olarak sağlıklı yenidoğan buzağılar (n=10) kullanıldı. Trombosit (PLT), aktive edilmiş parsiyel tromboplastin zamanı (APTT), protrombin zamanı (PT), trombin zamanı (TT), fibrin/fibrinojen yıkım ürünleri (FDPs) ve fibrinojen düzeylerini belirlemek için doğumdan itibaren 2 ila 12. saatleri arasında tüm buzağılardan kan örnekleri toplandı. Sağlıklı yenidoğan buzağılarla karşılaştırıldığında, premature buzağılarda APTT (P<0.001) ve PT’de (P<0.01) uzama, fibrinojen konsantrasyonunda (P<0.001) düşme ve trombosit sayısı azalma (P<0.001) tespit edildi. Premature buzağıların 8’inde TT’da istatistiksel olarak önemsiz bir uzama ve aynı zamanda bu buzağıların 2’sinde de anormal FDPs bulgusu kaydedildi. Prematüre buzağıların 6’sında istatistiksel olarak önemsiz, fakat anormal FDPs bulgusu tespit edildi. Sonuç olarak, respiratorik distres sendromlu premature buzağılarda anormal koagülasyon profi li belirlendi ve bu buzağıların 7’si yoğun tedaviye rağmen öldü. Veteriner Hekimler respiratorik distres sendromlu premature buzağıların tedavisinde bu sonuçları göz önünde tutarak uygun bir tedavi yöntemi geliştirebilirler. Ayrıca, bu bulgular yapılacak çalışmalara temel oluşturabilir.

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Cite This Article

IRMAK, K., TURGUT, K. (2011). Respiratorik distres sendromlu spontan premature buzağılarda koagulasyon profi linin değerlendirilmesi. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 17 - Sayı: 2, 197–201. https://ajindex.com/articles/273260

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