SavedAdd your journal

Journals / Medical Network Klinik Bilimler ve Doktor / 2004 / Cilt: 10 - Sayı: 4

Multiple cerebral abscesses formation during the corticosteroid use: Case report

Kortikosteroid kullanımı esnasında gelişen multipl serebral abseler: Olgu sunumu

Fahri ŞAHİN
Güray SAYDAM
Kezban Pınar ÖZEN
ÖMER KİTİŞ
Cem ÇALLI
Serdar Bedii OMAY
Pages
390–394
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We, here, present a case with the multiple cerebral abscesses developed under the steroid treatment due to immune thrombocytopenia.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Even though they have a lot of side effects, corticosteroids have been in a many treatment protocols in the treatment of different kinds of disease.
📊
Key Findings & Data:The most important side effect of steroids, especially in immun-comprimised patients, is still infections.
💡
Conclusion & Impact:We, here, present a case with the multiple cerebral abscesses developed under the steroid treatment due to immune thrombocytopenia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Adrenal korteks hormonları · Beyin apsesi · Adrenal Cortex Hormones

Abstract

Even though they have a lot of side effects, corticosteroids have been in a many treatment protocols in the treatment of different kinds of disease. The most important side effect of steroids, especially in immun-comprimised patients, is still infections. Dose of steroids, the application way and the duration are the most predisposing effects in the steroid-related infections. Parenteral use, long term use and high dosage have more potentiality in the risk of infection than low dose, short term and topical or inhaler usage. Although skin infections, pneumonia and otitis media have been the most frequent infections, less often, it is also possible to diagnose severe pneumocystitis carinii or aspergillus pneumonia and intra-abdominal abscess. It is very rare to detect intra-cerebral multiple abscesses in the patients using steroids. We, here, present a case with the multiple cerebral abscesses developed under the steroid treatment due to immune thrombocytopenia.

Özet

Yan etkilerinin fazla olmasına karşın hala günümüzde birçok hastalığın tedavi protokolleri içinde yerini alan steroidlerin özellikle immünsüprese hastalarda beraberinde getirdiği en önemli risk fırsatçı enfeksiyonlardır. Kullanılan steroidin dozu, uygulama şekli ve süresi predispozisyonu etkileyen en önemli etkenlerdir. Parenteral, uzun süre, yüksek dozda kullanımlarda enfeksiyon riski daha fazla iken düşük dozda, kısa etkili ve topikal veya inhaler kullanımda risk en düşüktür. Bu enfeksiyonlar içinde cilt enfeksiyonları, akciğer enfeksiyonları, otitis media en sık karşılaşılan enfeksiyonlar olmakla birlikte mortalitesi yüksek olabilen pnömosistis carinii enfeksiyonu, aspergillus enfeksiyonları, batın içi abseleri de görülebilmektedir. Steroid kullanımına bağlı gelişen beyin absesi daha nadir görülmektedir. Biz bu yazımızda immün trombositopeni nedeniyle kortikosteroid kullanan ve tedavi altında iken nörolojik bulgular gelişmesi üzerine yapılan kraniyal bilgisayarlı tomografi ve manyetik rezonans görüntüleme yöntemleri ile tanısı konan multipl serebral abseli bir olguyu sunmaktayız.

🔖

Cite This Article

ŞAHİN, F., SAYDAM, G., ÖZEN, K. P., KİTİŞ, Ö., ÇALLI, C., OMAY, S. B. (2004). Multiple cerebral abscesses formation during the corticosteroid use: Case report. Medical Network Klinik Bilimler ve Doktor, Cilt: 10 - Sayı: 4, 390–394. https://ajindex.com/articles/273049

References (14)

  1. Rosenblum ML, Hoff JT, Norman D, Weinstein PR, Pitts L. Decreased mortality from brain abscesses since advent of computerized tomography. J Neurosurg. 1978; 49:658-68.
  2. Bidzinski J, Koszewski W. The value of different methods of treatment of brain abscess in the CT era. Acta Neurochir (Wien). 1990; 105:117-20.
  3. Rau CS, Chang WN, Lin YC, et al. Brain abscess caused by aerobic Gram-negative bacilli: clinical features and therapeutic outcomes. Clin Neurol Neurosurg. 2002; 105:60-5.
  4. Lu CH, Chang WN, Chuang YC, Lu CH, Chang HW. Gram- negative bacillary meningitis in adult post-neurosurgical patients. Surg Neurol. 1999; 52:438-43. Zunt JR. Central nervous system infection during immunosuppression. Neurol Clin. 2002; 20:1-22.
  5. Klein NC, Go CH, Cünha BA. Infections associated with steroid use. Infect Dis Clin North Am. 2001; 15:423-32. Yang SY. Brain abscess: a review of 400 cases. J Neurosurg. 1981; 55:794-9.
  6. Osenbach RK, Loftus CM. Diagnosis and management of brain abscess. Neurosurg Clin N Am. 1992; 3:403-20
  7. Review. Liliang PC, Lin YC, Su TM, et al. Klebsiella brain abscess in adults. Infection. 2001; 29:81 -6. Lu CH, Chang WN, Lin YC, et al. Bacterial brain abscess: microbiological features, epidemiological trends and therapeutic outcomes.QJM 2002; 95:501-9.
  8. Wang JH, Liu YC, Lee SS, et al. Primary liver abscess due to Klebsiella pneumoniae in Taiwan.Clin Infect Dis. 1998; 26:1434-8.
  9. Rambeloarisoa J, Batisse D, Thiebaut JB, et al. Intramedul- lary abscess resulting from disseminated cryptococcosis despite immune restoration in a patient with AIDS. J Infect. 2002; 44:185-8. Kitthaweesin K. Upward gaze paralysis as the initial manifestation of HIV-infected patient: a case report. J Med Assoc Thai. 2002; 85:728-32.
  10. New PFJ, Davis KR, Ballantine HT Jr. Computed tomography in cerebral abscess. Radiology 1976; 121:641-6.
  11. Borm W, Gleixner M. Nocardia brain abscess misinterpreted as cerebral infarction. J Clin Neurosci. 2003; 10:130-2.
  12. Marchbank ND, Howlett DC, Sallomi DF, Hughes DV. Magnetic resonance imaging is preferred in diagnosing suspected cerebral infections. BMJ. 2000; 320:187-8.
  13. Bidzinski J, Koszewski W. The value of different methods of treatment of brain abscess in the CT era. Acta Neurochir (Wien). 1990; 105:117-20.
  14. Barlas O, Sencer A, Erkan K, Eraksoy H, Sencer S, Bayindir C. Stereotactic surgery in the management of brain abscess. Surg Neurol. 1999; 52:404-10.