Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2013 / Cilt: 19 - Sayı: 0

Determination of diagnostic and prognostic importance of the D (-) and L (+) lactic acid and some biochemical and hematological parameters in holstein dairy cows with abomasal displacement

Abomazum deplasmanlı sütçü sığırlarda D (-) ve L (+) laktik asit ile bazı biyokimyasal ve hematolojik parametrelerin diagnostik ve prognostik açıdan öneminin belirlenmesi

Pages
167–173
DOI
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⚡ TL;DR(Too Long; Didn't Read)

For that reason, D (-) and (L+) lactic acid levels may be prognostic criterion in cattle with right abomasal displacement at preoperative period.

📌 3 Key Takeaways

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Objective & Hypothesis:The purpsose of the present study was to evaluate of diagnostic and prognostic importance of the D (-) and L (+) lactic acid and some biochemical and hematological parameters of cattle with abomasal displacement.
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Key Findings & Data:In this study, 10 cattle with right abomasal displacement, 10 cattle with left abomasal displacement and 10 healthy (control) cattle, totally 30 dairy cattle in diff erent groups were used.
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Conclusion & Impact:For that reason, D (-) and (L+) lactic acid levels may be prognostic criterion in cattle with right abomasal displacement at preoperative period.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The purpsose of the present study was to evaluate of diagnostic and prognostic importance of the D (-) and L (+) lactic acid and some biochemical and hematological parameters of cattle with abomasal displacement. In this study, 10 cattle with right abomasal displacement, 10 cattle with left abomasal displacement and 10 healthy (control) cattle, totally 30 dairy cattle in diff erent groups were used. Mean blood pH, HCO3 - and SO2, values (P<0.01), mean value of BE (P<0.001); mean value of pvCO2 and Cl- (P<0.05) were found statistically significant. Higher D (-) and L (+) lactic acid levels in cattle with right abomasal displacement, and higher L (+) lactic acid levels in cattle with left abomasal displacement were observed and statistically significant diff erences were found than healthy cattle (P<0.001). Statistically significant diff erences were observed between groups at mean values of GGT, ALP, LDH and AST levels (P<0.05). Mean values of total leukocytes, hematocrit and hemoglobin levels between groups were statistically significant (P<0.05). As a result, L+LA levels in blood was increased, because of the fatty liver and impaired lactate metabolism in cattle with left abomasal displacement and both D and L+LA levels increased in cattle with right abomasal displacement due to abomasal ischemia, necrosis and impaired intestinal defense, and 3 cattle died. For that reason, D (-) and (L+) lactic acid levels may be prognostic criterion in cattle with right abomasal displacement at preoperative period.

Özet

Bu araştırmanın amacı, abomazum deplasmanlı ineklerde D(-) ve L(+) laktik asit ile bazı biyokimyasal ve hematolojik parametrelerin tanı ve prognozdaki önemini değerlendirmektir. Çalışmada, 10 sağa, 10 sola abomazum deplasmanlı ve 10 sağlıklı (kontrol) olmak üzere 3 farklı grupta toplam 30 süt ineği kullanıldı. Çalışmada kan pH, HCO3 - ve SO2, ortalama değerleri P<0.01, BE ortalama değerleri P<0.001, pvCO2 ve Cl- ortalama değerleri ise P<0.05 düzeyinde önemli bulundu. Sağa abomazum deplasmanlı (RDA) hayvanlarda D (-) ve L (+) laktik asit, sola abomazum deplasmanlı (LDA) hayvanlarda ise L (+) laktik asit düzeyi sağlıklı hayvanlardan daha yüksek olup, gruplar arası ortalama değerler istatistiksel anlamda önemli (P<0.001) bulundu. Gruplar arası GGT, ALP, LDH ve AST ortalama değerleri istatistiksel anlamda farklı (P<0.05) bulundu. Total lökosit, hematokrit ve hemoglobin ortalama değerlerinin gruplar arası farkı önemli bulundu (P<0.05). Sonuç olarak, LDA’lı ineklerde karaciğer yağlanması ve laktat metabolizmasının bozulması nedeniyle kanda L+LA miktarının, RDA’lı ineklerde ise, abomazumdaki işemi, nekroz ve bağırsak savunmasının bozulması sonucu D ve L+LA miktarının yükseldiği ve üç ineğin öldüğü saptanmıştır. Bu nedenle, RDA’lı ineklerin prognozunu değerlendirmede, operasyon öncesi D ve L+LA miktarı önemlidir.

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Cite This Article

SEZER, K., ŞAHİNDURAN, Ş., ALBAY, M. K., KARAKURUM, M. Ç. (2013). Determination of diagnostic and prognostic importance of the D (-) and L (+) lactic acid and some biochemical and hematological parameters in holstein dairy cows with abomasal displacement. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 19 - Sayı: 0, 167–173. https://ajindex.com/articles/272911

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References (14)

  1. Blood DC, Radostits OM: Veterinary Medicine. 10th ed., Bailliere Tindall, London. 2007
  2. Karakurum MC, Albay MK, Sahinduran S, Sezer K: Coagulation parameters in cattle with left displacement of abomasum. Kafkas Univ Vet Fak Derg, 15 (2): 293-296, 2009
  3. Geishauser T, Leslie K, Duffield T, Edge V: An evaluation of milk ketone tests for the prediction of left displaced abomasum in dairy cows. J Dairy Sci, 80 (12): 3188-3192, 1997
  4. Fubini SL, Gröhn YT, Smith DF: Right displacement of the abomasum and abomasal volvulus in dairy cows: 458 cases (1980-1987). J Am Vet Med Assoc, 198 (3): 460-464, 1991
  5. Karapınar T, Köm M, Dabak M: Sola abomazum deplasmanlı bir inekteki ultrasonografik bulgular. Doğu Anadolu Bölgesi Araştırmaları, 5, 19-22, 2006
  6. Kalaitzakis E, Panousis N, Roubies N, Kaldrymidou E, Karatzias H: Macromineral status of dairy cows with concurrent left abomasal displacement and fatty liver. N Z Vet J, 58 (6): 307-311, 2010
  7. Rohn M, Tenhagen BA, Hofmann W: Survival of dairy cows after surgery to correct abomasal displacement: 2. Association of clinical and laboratory parameters with survival in cows with left abomasal displacement. J Vet Med Assoc 51 (6): 300-305, 2004
  8. Stengarde LU, Holtenius K, Traven M, Hultgren J, Niskanen R, Emanuelson U: Blood profiles in dairy cows with displaced abomasum. J Dairy Sci, 93 (10): 4691-4699, 2010
  9. Geishauser T, Leslie K, Duffield T: Metabolic aspects in the etiology of displaced abomasum. Vet Clin North Am: Food Anim Pract, 16 (2): 255- 265, 2000
  10. Staufenbiel R, Ahmed MM, Baumgartner W, Gelfert CC: The use biochemical and hepatic parameters to predict treatment outcome of dairy cows suff ering from displacement of the abomasum. Dtsch Tierarztl Wochenschr, 114 (6): 225-230, 2007
  11. Yılmaz Z, Seyrek İD, Şentürk S, Gölcü E, İlçöl Y, Görgül S: Sağ ve sol abomasum deplasmanlı ineklerde operasyon öncesi ve sonrası dönemde biyokimyasal parametrelerin değerlendirilmesi. Vet Cerrahi Derg, 8 (3-4): 20-26, 2002
  12. El-Attar HM, Yassein AE, Ghanem MM: Alterations in the clinical, hematological and biochemical pictures in abomasal displacement in cows in Egypt. BS Vet Med J, 5th Scientific Conference,102-109, November, 2007
  13. Abeysekara S, Jonathan M, Naylor MJ, Andrew WA, Isak U, Zello GA: D-Lactic acid-induced neurotoxicity in a calf model. Am J Physiol Endocrinol Metab, 293, 558-565, 2007
  14. Cady LD, Weil MH, Afifi AA: Quantitation of severity of critical illness with special reference t