Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2015 / Cilt: 21 - Sayı: 3

Aflatoksin Sindirilmesi Sonucu Akut Mortalite Şekillenen Domuz Yavrularında Adli Bulgular

Forensic Findings on Acute Mortality of Piglets after Ingestion of Aflatoxin

Pages
437–440
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After removal of the contaminated feed, the number of deaths began to reduce, as well as the clinical symptoms typical for AF

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aflatoxin (AF) is one of the most significant mycotoxins in pigs and results in a significant decrease of production performance.
📊
Key Findings & Data:Within 7 days, 420 suckling piglets aged 20±3 days died on a farm.
💡
Conclusion & Impact:After removal of the contaminated feed, the number of deaths began to reduce, as well as the clinical symptoms typical for AF
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aflatoxin (AF) is one of the most significant mycotoxins in pigs and results in a significant decrease of production performance. This paper describes the first case of acute effects of AF in suckling piglets in Serbia. Within 7 days, 420 suckling piglets aged 20±3 days died on a farm. Forensic findings included a medical history, clinical presentation with pathomorphological and histopathological confirmation of intoxication of the piglets with AF. Detection of AF in sows' milk (870 µg/kg), which was the primary nutriment for the piglets, confirmed the suspicion of AF intoxication. The piglets at that age also consumed solid feed, which was found to be contaminated with AF (960 µg/kg), and which accelerated the process of intoxication. After removal of the contaminated feed, the number of deaths began to reduce, as well as the clinical symptoms typical for AF

Özet

Aflatoksin (AF) domuzlarda rastlanan en önemli mikotoksinlerden biri olup üretim performansında önemli azalmalara sebebiyet verir. Bu vaka takdimi süt emme dönemindeki domuz yavrularında AF'nin akut ektilerini gösteren Sırbistan'daki ilk çalışmadır. Bir çiftlikte 7 günlük bir süreçte yaşları 20±3 gün arasında değişen 420 adet domuz eniği ölü bulundu. Anamnez, klinik bulgular, patomorfolojik ve histopatolojik bulgular AF toksikasyonunu şüphelendirdi. Temel besin kaynağı olarak annelerin sütünde AF belirlenmesi (870 µg/kg) AF toksikasyonunu teşhisini doğruladı. Katı yem de tüketen yavruların bu yemlerinde de AF belirlenmesi (960 µg/kg) toksikasyonun hızlı seyrini açıklar nitelikteydi. Kontamine yemin uzaklaştırılmasından sonra ölümlerde ve AF'nin tipik klinik bulgularında azalma tespit edildi.

🔖

Cite This Article

STOJANAC, N., STEVANCEVIC, O., SAVIC, B., DAVIDOV, I., CINCOVIC, R. M., POTKONJAK, A., SPASOJEVIC, J. (2015). Aflatoksin Sindirilmesi Sonucu Akut Mortalite Şekillenen Domuz Yavrularında Adli Bulgular. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 21 - Sayı: 3, 437–440. https://ajindex.com/articles/272554

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (5)

  1. Binder EM, Tan LM, Chin LJ, Handl J, Richard J: Worldwide occurrence of mycotoxins in commodities, feeds and feed ingredients. Anim Feed Sci Tech, 137, 265-282, 2007. DOI: 10.1016/j.anifeedsci.2007.06.005 Akkaya MR, Bal MA: Efficacy of modified yeast extract and HSCAS containing mycotoxin adsorbent on ruminal binding characteristics of various aflatoxins. Kafkas Univ Vet Fak Derg, 18, 951-955, 2012. DOI: 9775/kvfd.2012.6838 Bondy G, Pestka JJ: Immunomodulation by fungal toxins. J Toxicol Env Heal B, 3, 109-143, 2000. DOI: 10.1080/109374000281113 Mocchegiani E, Corradi A, Santarelli L, Tibaldi A, DeAngelis E, Borghetti P, Bonomi A, Fabris N, Cabassi E: Zinc, thymic endocrine activity and mitogen responsiveness (PHA) in piglets exposed to maternal aflatoxicosis B1 and G1. Vet Immunol Immunop, 62, 245-260, 1998. DOI: 1016/S0165-2427(98)00073-7
  2. Harms PA, Halbur PG, Sorden SD: Three cases of porcine respiratory disease complex associated with porcine circovirus type 2 infection. J Swine Health Prod, 10 (1): 27-30, 2002. Segalés J: Porcine circovirus type 2 (PCV2) infections: Clinical signs, pathology and laboratory diagnosis. Virus Res, 164, 10-19, 2012. DOI: 1016/j.virusres.2011.10.007 Stevancevic O, Stojanac N, Potkonjak A, Savic B, Stancic I, Gagrcin M, Vracar V: Immune response and production perfomance in piglets vaccinated at 15 and 21 days old against Circovirus infection. Kafkas Univ Vet Fak Derg, 20, 465-468, 2014. DOI: 10.9775/kvfd.2013.10373 Chaytor AC, See MT, Hansen JA, de Souza ALP, Middleton TF, Kim SW: Effects of chronic exposure of diets with reduced concentrations of aflatoxin and deoxynivalenol on growth and immune status of pigs. J Anim Sci, 89, 124-135, 2011. DOI: 10.2527/jas.2010-3005 FAO. Worldwide Regulations for Mycotoxins 1995. A Compendium. Food and Agriculture Organization of the United Nations, Rome, 1997.
  3. Marin DE, Taranu I, Bunaciu RP, Pascale F, Tudor DS, Avram N, Sarca M, Cureu I, Criste RD, Suta V, Oswald IP: Changes in performance, blood parameters, humoral and cellular immune responses in weanling piglets exposed to low doses of aflatoxin. J Anim Sci, 80, 1250-1257, 2002.
  4. Mok CH, Shin SY, Kim BG: Aflatoxin, deoxynivalenol, and zearalenone in swine diets: Predictions on growth performance. Rev Colomb Cienc Pecu, 26, 243-254, 2013.
  5. Meissonnier GM, Pinton P, Laffitt EJ, Cossalter A, Gong YY, Wild CP, Bertin G, Galtier P, Oswald IP: Immunotoxicity of aflatoxin B1: Impa1irment of the cell-mediated response to vaccine antigen and m