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Journals / Haseki Tıp Bülteni / 2012 / Cilt: 50 - Sayı: 1

Renal tubular functions in children with primary nocturnal enuresis

Primer nokturnal enürezisli çocuklarda renal tubuler fonksiyonlar

Süleyman KALMAN
Onur SAKALLIOĞLU
Vural KESİK
Faysal GÖK
Pages
10–13
DOI
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AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further studies are needed in order to investigate renal tubular functions in children with PNE (The Me di cal Bul le tin of Ha se ki 2012; 50: 10-3)

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: The etiology of primary nocturnal enuresis (PNE) is multifactorial.
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Key Findings & Data:The other factors include increased urine production at night and impairment of the circadian rhythm of antidiuretic hormone.
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Conclusion & Impact:Further studies are needed in order to investigate renal tubular functions in children with PNE (The Me di cal Bul le tin of Ha se ki 2012; 50: 10-3)
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: The etiology of primary nocturnal enuresis (PNE) is multifactorial. The effects of genetic and hormonal factors, sleep disorders, and bladder dysfunction have been claimed. The other factors include increased urine production at night and impairment of the circadian rhythm of antidiuretic hormone. Aim: To investigate renal tubular functions in children with PNE. Methods: Forty patients with PNE were included in the study. Urine density, FENa, FEK and TRP were analyzed in daytime and nighttime urine. Results: The mean nighttime urine density was 1020.12±7.38 and the mean daytime urine density was 1013.20±7.11 (p<0.05). There was no significant difference between daytime and nighttime values of FENa (0.50±0.48 vs. 0.38±0.33), FEK (2.78±1.04 vs. 2.76±1.52) and TRP (88.5±2.4 vs 86.7±2.8) (p>0.05). Conclusion: Urine density in children with PNE was lower at night. However, there was no difference in of FENa, FEK and TRP. Further studies are needed in order to investigate renal tubular functions in children with PNE (The Me di cal Bul le tin of Ha se ki 2012; 50: 10-3)

Özet

Giriş: Primer nokturnal enürezis (PNE) etiyolojisi multifaktöriyeldir. Genetik faktörler, uyku bozuklukları, mesane fonksiyon bozukluğu ve hormonal faktörlerin etkili olduğu ileri sürülmektedir. Etkili faktörlerden biri de gece çıkarılan idrar hacmindeki artış ve ADH’ın sirkadiyen ritminin bozulmasıdır. Amaç: PNE’lı olgularda, renal tubuler fonksiyonları araştırmaktır. Yöntem: Çalışmaya 18’i kız, 22’si erkek, yaş ortalaması 7,8±2,9 olan 40 PNE’lı olgu alındı. Bu olguların gece ve gündüz idrarları toplanarak, dansite, fraksiyone sodyum atılımı (FENa), fraksiyone potasyum atılımı (FEK) ve tubular fosfor reabsorpsiyonu (TRP) düzeyleri çalışıldı. Bulgular: Olguların gündüz ilk idrar dansitesi ortalaması 1020,12±7,38 bulunurken, gece idrar dansitesi 1013,20±7,11 bulundu (p 0,05) saptandı. Sonuç: İdrar dansiteleri PNE’li çocuklarda gece daha düşük saptandı. Ancak FENa, FEK ve TRP açısından bir fark bulunamadı. Renal tubuler fonksiyonların enürezisli olgulardaki yerini belirlemek açısından daha kapsamlı çalışmalara gerek olduğu kanısına varıldı. (Ha se ki T›p Bül te ni 2012; 50: 10-3)

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Cite This Article

KALMAN, S., SAKALLIOĞLU, O., KESİK, V., GÖK, F. (2012). Renal tubular functions in children with primary nocturnal enuresis. Haseki Tıp Bülteni, Cilt: 50 - Sayı: 1, 10–13. https://ajindex.com/articles/267971

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