SavedAdd your journal

Journals / Haseki Tıp Bülteni / 2012 / Cilt: 50 - Sayı: 1

Sclerosing stromal tumor of the ovary: A case report

Overin sklerozan stromal tümörü: Olgu sunumu

Ayşe Tülay SAYILGAN
Filiz FİLİZ
Deniz ÖZCAN
Pages
33–36
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A combination of morphological, immunohistochemical, radiological and clinical findings is needed in differentiating the tumor from thecoma, fibroma/fibrosarcoma, lipoid tumors and Krukenberg tumor. (The Me di cal Bul le tin of Ha se ki 2012; 50: 33-6)

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Sclerosing stromal tumor of the ovary is a rare benign ovarian tumor originating from sex-cord stroma.
📊
Key Findings & Data:Fewer than 120 cases have been described in the English literature.
💡
Conclusion & Impact:A combination of morphological, immunohistochemical, radiological and clinical findings is needed in differentiating the tumor from thecoma, fibroma/fibrosarcoma, lipoid tumors and Krukenberg tumor. (The Me di cal Bul le tin of Ha se ki 2012; 50: 33-6)
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Sclerosing stromal tumor of the ovary is a rare benign ovarian tumor originating from sex-cord stroma. Fewer than 120 cases have been described in the English literature. In this study, we report a 19-year-old patient, who underwent operation for suspected ovarian cancer due to elevated CA-125 levels and solid ovarian mass detected radiologically. Histologically, it is characterized by pseudolobular patern composed of hypocellular and hypercellular areas with abundant vascular structures. Intraoperative diagnosis of the tumor is extremely important, since it is mostly observed in young patients requiring conservative surgery. To identify its benignancy during intraoperative examination is sufficient for the selection of the appropriate surgical approach. A combination of morphological, immunohistochemical, radiological and clinical findings is needed in differentiating the tumor from thecoma, fibroma/fibrosarcoma, lipoid tumors and Krukenberg tumor. (The Me di cal Bul le tin of Ha se ki 2012; 50: 33-6)

Özet

Overin sklerozan stromal tümörü, seks-kord stroma kaynaklı nadir, benign bir over tümörüdür. İngilizce literatürde 120'den az olgu tanımlanmıştır. Çalışmamızda CA-125 yüksekliği ve radyolojik olarak solid görünümlü over kitlesinden dolayı malignite şüphesi ile opere edilen 19 yaşında olgu sunulmaktadır. Histolojik olarak tümör bol vasküler yapılar ile birlikte hücresel ve hiposellüler alanlardan oluşan karakteristik psödolobüler paterne sahiptir. Konservatif cerrahinin gerekli olduğu genç hastalarda görülmesi nedeniyle sklerozan stromal tümörün intraoperatif patolojik tanısı büyük önem taşır. İntraoperatif incelemede benign yönünde yanıt verilmesi doğru cerrahi girişimin yapılması için yeterlidir. Ayırıcı tanıda yer alan tekom, fibrom-fibrosarkom, lipoid tümörler ve Krukenberg tümöründen ayrımı için morfolojik, immünohistokimyasal, radyolojik ve klinik bulguların kombinasyonu gereklidir. (Ha se ki Tıp Bül te ni 2012; 50: 33-6)

🔖

Cite This Article

SAYILGAN, A. T., FİLİZ, F., ÖZCAN, D. (2012). Sclerosing stromal tumor of the ovary: A case report. Haseki Tıp Bülteni, Cilt: 50 - Sayı: 1, 33–36. https://ajindex.com/articles/267963

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Chalvardjian A, Scully RE. Sclerosing stromal tumors of the ovary. Cancer 1973;31:664-70
  2. Peng HH, Chang TC, Hsueh S. Sclerosing stromal tumor of ovary. Chang Gung Med J 2003;26:444-8
  3. Iravanloo G, Nozarian Z, Sarrafpour B, Motahhary P. Sclerosing stromal tumor of the ovary. Arch Iran Med 2008;11:561-2
  4. He Y, Yang KX, Jiang W, Wang DQ, Li L. Sclerosing stromal tumor of the ovary in a 4-year-old girl with characteristics of an ovarian signet-ring stromal tumor. Pathol Res Pract 2010;206:338-41
  5. Youm HS, Cha DS, Han KH, Park EY, Hyon NN, Chong Y. A case of huge sclerosing stromal tumor of the ovary weighing 10 kg in a 71-year-old postmenopausal woman. J Gynecol Oncol 2008;19:270-4
  6. Chang W, Oiseth SJ, Orentlicher R, Agarwal G, Yahr LJ, Cayten CG. Bilateral sclerosing stromal tumor of the ovaries in a premenarchal girl. Gynecol Oncol 2006;101:342-5
  7. Chang YW, Hong SS, Jeen YM, Kim MK, Suh ES. Bilateral sclerosing stromal tumor of the ovary in a premenarchal girl. Pediatr Radiol 2009;39:731-4
  8. Hall OR, Pascasio JM, Morrissette JJ, Newton C, Schwartz MZ, de Chadarévian JP. Study of an ovarian sclerosing stromal tumor presenting as vaginal bleeding in a 7-month-old. Pediatr Dev Pathol 2008;11:300-4
  9. Uğuralp S, Güngör A, Sığırcı A, Şamdancı E, Aydın E. Overin nadir görülen sklerozan stromal tümörü: Olgu sunumu. Çocuk Cerrahisi Dergisi 2009;23:85-8
  10. Kurt G, İlhan R, Yavuz E, TUZLALI S, İPLİKÇİ A. Overin sklerozan stromal tümörleri: Altı olgu üzerinde morfolojik ve immünhistokimyasal analiz. Türk Patoloji Dergisi 2004;20:66-8
  11. Andrade LA, Gentilli AL, Polli G. Sclerosing stromal tumor in an accessory ovary. Gynecol Oncol 2001;81:318-9
  12. Kawauchi S, Tsuji T, Kaku T, Kamura T, Nakano H, Tsuneyoshi M. Sclerosing stromal tumor of the ovary: a clinicopathologic, immunohistochemical, ultrastructural, and cytogenetic analysis with special reference to its vasculature. Am J Surg Pathol 1998;22:83-92
  13. Ishioka S, Sagae S, Saito T, et al. A case of a sclerosing stromal ovarian tumor that expresses VEGF. J Obstet Gynaecol Res 2000 Feb;26:35-8
  14. Irving JA, McCluggage WG. Ovarian spindle cell lesions: a review with emphasis on recent developments and differential diagnosis. Adv Anat Pathol 2007;14:305-19
  15. Terauchi F, Onodera T, Nagashima T, et al. Sclerosing stromal tumor of the ovary with elevated CA-125. J Obstet Gynaecol Res 2005;31:432-5
  16. Mikami M, Fukuchi T, Takehara K, Komiyama S, Suzuki A, Hirose T. Tumor imprint cytolo