SavedAdd your journal

Journals / Haseki Tıp Bülteni / 2014 / Cilt: 52 - Sayı: 1

Evaluation of the Analgesic Efficacy of Dexketoprofen and Tramadol in Thyroid Surgery

Tiroid Cerrahisinde Deksketoprofen ve Tramadolün Analjezik Etkinliğinin Değerlendirilmesi

Ayşe Çiğdem TÜTÜNCÜ
Birsel EKİCİ
Ayşenur YEKSAN
Fatiş ALTINDAŞ
Güner KAYA
Pages
5–9
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The incidence of headache, sore throat nausea, vomiting was higher in Group K compared with that in Group T and Group D.Conclusion: We determined that preoperative tramadol and dexketoprofen had similar analgesic effect and dexketoprofen caused less side-effects

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: The aim of this study was to evaluate the analgesic efficacy and side-effects of dexketoprofen and tramadol administered intravenously before thyroid surgery.Methods: A group of 63 patients, who were graded as American Society of Anaesthesiologists physical status (ASA) I-II and in whom a thyroid surgery was planned, were randomly divided into 3 groups: the patients in Group D (n=21), Group T (n=21) and Group K (n=21) received 50 mg (2ml) of dexketoprofen, 100 mg (2 ml) of tramadol and 2 ml 0.9% NaCl serum, respectively, before surgery.
📊
Key Findings & Data:At the end of the surgery, the incision line was infiltrated with bupivacaine in all patients.
💡
Conclusion & Impact:The incidence of headache, sore throat nausea, vomiting was higher in Group K compared with that in Group T and Group D.Conclusion: We determined that preoperative tramadol and dexketoprofen had similar analgesic effect and dexketoprofen caused less side-effects
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The aim of this study was to evaluate the analgesic efficacy and side-effects of dexketoprofen and tramadol administered intravenously before thyroid surgery.Methods: A group of 63 patients, who were graded as American Society of Anaesthesiologists physical status (ASA) I-II and in whom a thyroid surgery was planned, were randomly divided into 3 groups: the patients in Group D (n=21), Group T (n=21) and Group K (n=21) received 50 mg (2ml) of dexketoprofen, 100 mg (2 ml) of tramadol and 2 ml 0.9% NaCl serum, respectively, before surgery. Standard anesthesia monitoring, induction and maintenance was performed in all patients. At the end of the surgery, the incision line was infiltrated with bupivacaine in all patients. Visual analogue scale (VAS) scores (0: no pain,10: worst pain ever) were recorded in all groups at the beginning (in the recovery room), at the 1st, 6th, 12th and 24th hour post-operatively. Nausea-vomiting, head and neck pain, sore throat, dizziness and other possible sideeffects were also asked and recorded. Results: VAS scores were statistically higher in Group K than in Group T and Group D at the 1st, 6th, 12th, and 24th hours postoperatively. There was no significant difference between Group T and Group D in VAS scores evaluated at all time points.. The fentanyl consumption in Group K was higher than in the other two groups. The incidence of headache, sore throat nausea, vomiting was higher in Group K compared with that in Group T and Group D.Conclusion: We determined that preoperative tramadol and dexketoprofen had similar analgesic effect and dexketoprofen caused less side-effects

Özet

Amaç: Bu çalışmada, tiroid cerrahisi öncesi intravenöz olarak verilen deksketoprofen ve tramadolün analjezik etkinliği ve yan etki sıklığının araştırılması amaçlanmıştır. Yöntemler: Tiroid cerrahisi planlanan ASAI-II 63 hasta rastgele 3 gruba ayrılarak, ameliyattan önce Grup D'ye (n=21) 50 mg 2 ml deksketoprofen, Grup T'ye (n=21) 100 mg 2 ml tramadol ve Grup K'ya (n=21) 2 mL izotonik serum intravenöz yolla verilmiştir. Tüm hastalarda standart anestezi monitorizasyonu, indüksiyonu ve idamesi sağlanmıştır. Tüm hastalara cerrahi bitiminde insizyon hattına bupivakain infiltrasyonu uygulanmıştır. Ağrı değerlendirmesi Verbal Analog Skala (VAS) ile yapılmıştır. Her üç hasta grubunda postoperatif 0. saat (derlenme), postoperatif 1. saat, 6. saat, 12. saat ve 24. saatlerde ağrı, bulantı-kusma, baş-boyun ağrısı, boğaz ağrısı, baş dönmesi ve diğer yan etkiler kaydedilmiştir.Bulgular: Postoperatif 1, 6, 12. ve 24. saatlerde VAS skorları, Grup K'da Grup T ve Grup D'ye göre istatistiksel olarak anlamlı yüksek bulunmuştur. Grup T ve Grup D arasında tüm zamanlarda VAS skorları açısından istatistiksel olarak anlamlı fark bulunmamıştır. Peroperatif fentanil tüketimi Grup K'da anlamlı olarak yüksek bulunmuştur. Kontrol grubunda baş ağrısı, boğaz ağrısı, bulantı sıklığı, Grup T ve Grup D'ye göre istatistiksel olarak anlamlı derecede fazla bulunmuştur.Sonuç: Tiroid cerrahisi öncesi tramadol ve deksketoprofen kullanımının, benzer analjezik etkinliğe sahip olduğu, deksketoprofen grubunda yan etki sıklığının her iki gruba göre daha az olduğu saptanmıştır

🔖

Cite This Article

TÜTÜNCÜ, A. Ç., EKİCİ, B., YEKSAN, A., ALTINDAŞ, F., KAYA, G. (2014). Evaluation of the Analgesic Efficacy of Dexketoprofen and Tramadol in Thyroid Surgery. Haseki Tıp Bülteni, Cilt: 52 - Sayı: 1, 5–9. https://ajindex.com/articles/267872

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Basto ER, Waintrop C, Mourey DF, Landru PJ, Eurin GB, Jacob PL. Intravenous Ketoprofen in Thyroid and Parathyroid Surgery. Anesth Analg 2001;92:1052-7.
  2. Dieudonne N, Alexandra Gomola A, Bonnichon P, Ozier YM. Prevention of Postoperative Pain After Thyroid Surgery:A Double-Blind Randomized Study of Bilateral Superficial Cervical Plexus Blocks. Anesth Analg 2001;92:1538-42.
  3. Ong CKS, Lirk P, Seymour RA, Jenkins BJ. The Efficacy of Preemptive Analgesia for AcutePostoperative Pain Management: A Meta-Analysis. Anesth Analg 2005;100:757-73.
  4. Zhang Z, Zhao H, Wang C, Han F, Wang G. Lack of Preemptive Analgesia by Intravenous Flurbiprofen in Thyroid Gland Surgery: A Randomized, Double-blind and Placebo-controlled Clinical Trial. Int. J. Med. Sci 2011;8:433-8.
  5. Atalay C, Doğan N, Kızılkaya M, Kürsad H, Coşkun A. The effects of preemptive intravenous dexketoprofen trometamol on quality of patient controlled analgesia after abdominal hysterectomy. J Clin Anal Med 2012;3:134-7.
  6. Reuben SS, Bhopatkar S, Maciolek H, et al. The preemptive analgesic effect of rofecoxib after ambulatory arthroscopic knee surgery. Anesth Analg 2002; 94: 55-69. Katz J. Preemptive analgesia; importance of timing. Can J Anaesth 2001;48:105-14.
  7. Ong CK, Lirk P, Seymour RA, Jenkins BJ. The efficacy of preemptive analgesia for acute postoperative pain management: a meta analysis. Anest Analg 2005;100:753-73.
  8. Moore RA, Barden J. Systematic review of dexketoprofen in acute and chronic pain. BMC Clin Pharma 2008;8:4-11.
  9. Scott LJ, Perry MC. Tramadol A Review of its Use in Perioperative Pain. Drugs 2000;60:139-76.
  10. Lohsiriwat V, Lert-akyamanee N, Rushatamukayanunt W. Efficacy of pre-incisional bupivacaine infiltration on postoperative pain relief after appendectomy: prospective double-blind randomized trial. World J Surg 2004;28:947-50.
  11. Young A, Buvanendran A. Recent advances in multimodal analgesia. Anesthesiol Clin 2012;30:91-100.
  12. Mchardy FE, Chung F. Postoperative sore throat: cause, prevention and treatment. Anaesthesia 1999;54:444-53.
  13. Hisham AN, Roshilla H, Amri N, Aina EN. Post-thyroidectomy sore throat following endotracheal intubation. ANZ J Surg 2001;71:669-71.
  14. Sonner JM, Hynson JM, MD, Clark O, Katz JA. Nausea and Vomiting Following Thyroid and Parathyroid Surgery. J Clin Anesth 1997;9:398-402.
  15. Buvanendran A, Kroin SJ Multimodal analgesia for controlling acute postoperative pain. Curr Opin Anaesthesiol 2009;22:588- 593.