SavedAdd your journal

Journals / Haseki Tıp Bülteni / 2014 / Cilt: 52 - Sayı: 3

Predictive Value of Endometrial Thickness in Detecting Endometrial Malignancy in Patients with Postmenopausal Bleeding

Postmenopozal Kanamalı Hastalarda Endometrial Kalınlığın Endometrial Maligniteyi Saptamadaki Öngörüsü

Onur KAYA
Cem Dane
Ecem KAYA
Mehmet Murat SEMİZ
Ahmet ÇETİN
Gamze SAYGI
Pages
164–167
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In our study, when a endometrial thickness cutoff value of 10.8 mm was taken, the sensitivity, specificity, and negative predictive value was found to be 84%, 52%, and 96%, respectively.Conclusion: In our study, almost all patients (96%) with endometrial thickness of less than 10.8 mm, were free from endometrial malignancy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: The aim of this study was to investigate the place of endometrial thickness in detecting endometrial malignancy in patients with postmenopausal vaginal bleeding.Methods: In this study, we retrospectively evaluated hospital records of 380 patients who had undergone endometrial biopsy with the diagnosis of postmenopausal bleeding in the Department of Obstetrics and Gynecology at Haseki Training and Research Hospital between January 2008 and January 2012.
📊
Key Findings & Data:Results: Analysis of the biopsy specimens revealed benign or premalignant endometrium in 355 of the 380 patients who were histopathologically diagnosed with postmenopausal bleeding.
💡
Conclusion & Impact:In our study, when a endometrial thickness cutoff value of 10.8 mm was taken, the sensitivity, specificity, and negative predictive value was found to be 84%, 52%, and 96%, respectively.Conclusion: In our study, almost all patients (96%) with endometrial thickness of less than 10.8 mm, were free from endometrial malignancy.
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: The aim of this study was to investigate the place of endometrial thickness in detecting endometrial malignancy in patients with postmenopausal vaginal bleeding.Methods: In this study, we retrospectively evaluated hospital records of 380 patients who had undergone endometrial biopsy with the diagnosis of postmenopausal bleeding in the Department of Obstetrics and Gynecology at Haseki Training and Research Hospital between January 2008 and January 2012. Results: Analysis of the biopsy specimens revealed benign or premalignant endometrium in 355 of the 380 patients who were histopathologically diagnosed with postmenopausal bleeding. The mean endometrial thickness in 25 patient with malign endometrium was 11.6±8.2 mm. In our study, when a endometrial thickness cutoff value of 10.8 mm was taken, the sensitivity, specificity, and negative predictive value was found to be 84%, 52%, and 96%, respectively.Conclusion: In our study, almost all patients (96%) with endometrial thickness of less than 10.8 mm, were free from endometrial malignancy.

Özet

Amaç: Bu çalışma postmenopozal vaginal kanaması olan hastalarda endometrial kalınlığın maligniteyi saptamadaki yerini araştırmak amacıyla yapılmıştır.Yöntemler: Haseki Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum Kliniği'nde Ocak 2008-Ocak 2012 tarihleri arasında postmenopozal vaginal kanama tanısı ile endometriyal biopsi işlemi yapılan 380 hastanın kayıtlarının retrospektif olarak incelenmesi ile yapıldı.Bulgular: Çalışmaya alınan postmenopozal kanaması olan ve endometrial örnekleme sonucu ile histopatolojik tanı konabilen 380 hastadan histolojik tanılarına göre 355 hasta benign veya premalign olarak değerlendirildi. Malign saptanan 25 hastanın ortalama endometrial kalınlığı 11,6±8,2 saptandı. Çalışmamızda endometrial kalınlık için sınır değer 10,8 mm alındığında maligniteyi belirlemede sensitivite %84, spesifite %52 bulunurken, negatif belirleyicilik değeri %96 olarak saptanmıştır.Sonuç: Çalışmamızın sonucunda endometrial kalınlığı 10,8 mm'nin altında olan hastaların çoğunluğunda (%96) endometrial maligniteye rastlanmayacağı söylenebilir.

🔖

Cite This Article

KAYA, O., Dane, C., KAYA, E., SEMİZ, M. M., ÇETİN, A., SAYGI, G. (2014). Predictive Value of Endometrial Thickness in Detecting Endometrial Malignancy in Patients with Postmenopausal Bleeding. Haseki Tıp Bülteni, Cilt: 52 - Sayı: 3, 164–167. https://ajindex.com/articles/267853

References (9)

  1. Creinin MD. Evaluation of postmenapouseal bleeding. Am J Obstet Gynecol 1998;178:868-9.
  2. Burbos N, Musonda P, Giarenis I, et al. Predicting the risk of endometrial cancer in postmenopausal women presenting with vaginal bleeding: the Norwich DEFAB risk assessment tool. Br J Cancer 2010:102:1201-6.
  3. Dijkhuizen FP, Mol BW, Brölmann HA, Heintz AP. The accuracy of endometrial sampling in the diagnosis of patients with endometrial carcinoma and hyperplasia: a meta-analysis. Cancer 2000:89:1765-72.
  4. Dijkhuizen FP, Brölmann HA, Potters AE, Bongers MY, Heinz AP. The accuracy of transvaginal ultrasonography in the diagnosis of endometrial abnormalities. Obstet Gynecol 1996:87:345- 9. Granberg S, Wikland M, Karlsson B, Norström A, Friberg LG. Endometrial thickness as measured by endovaginal ultrasonography for identifying endometrial abnormality. Am J Obstet Gynecol 1991;164:47-52.
  5. Karlsson B, Granberg S, Wikland M, et al. Transvaginal ultrasonography of the endometrium in women with postmenopausal bleeding--a Nordic multicenter study. Am J Obstet Gynecol 1995;172:1488-94.
  6. Smith-Bindman R, Kerlikowske K, Feldstein VA, et al. Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities. JAMA 1998;280:1510-7.
  7. Turfanda A, Topuz S. "Menopoz", Jinekoloji. Berkman S, editor.Nobel Tıp Kitabevleri Ltd.Şti, İstanbul; 2004:87-97. Hurd WW. Abnormal Bleeding. In: Berek JS, Adashi EY, Hillard PA, editors. Menopause. Novak's Gynecology. Pennsylvania. Williams & Wilkins Company; 1996.
  8. Cho HJ, Lee ES, Lee JY, et al. Investigations for postmenopausal uterine bleeding: special considerations for endometrial volume. Arch Iran Med 2013;16:665-70. American College of Obstetricians and Gynecologists. ACOG Committee Opinion No. 426: The role of transvaginal ultrasonography in the evaluation of postmenopausal bleeding. Obstet Gynecol 2009:113:462-4.
  9. Selçuk S, Asoğlu MR, Çelik C, Tuğ N, Çam Ç, Karateke A. Postmenopozal Vajinal Kanamalı Hastalarda Endometrial Kalınlıkla Histopatoloji Sonuçları Arasındaki İlişki. Zeynep Kamil Tıp Bülteni 2011;42:7-12.