Journals / Haseki Tıp Bülteni / 2017 / Cilt: 55 - Sayı: 3

Comparison of the Effects of Haloperidol and Benzodiazepines Used for Postictal Psychiatric Symptoms on Seizure Recurrence: A Pilot Study

Postiktal Psikiyatrik Semptomlarda Benzodiazepin ve Haloperidolün Nöbet Tekrarına Etkilerinin Karşılaştırılması

Pages
175–180
DOI
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Bonferroni correction was performed for post-hoc analysis.Results: There were no differences in the seizure recurrence rate between benzodiazepine, haloperidol and without medication groups (p>0.05).Conclusion: Our results suggest that benzodiazepines and haloperidol do not affect the development of recurrent seizures when administered for postictal symptoms.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Patients with epilepsy may experience a number of psychiatric and cognitive symptoms or behavioral manifestations during the period of a seizure and the postictal period.
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Key Findings & Data:The aim of this pilot study was to compare the effects medications commonly used in emergency departments for postictal psychiatric symptoms on seizure recurrence.Methods: Data of 32 epileptic patients, who presented to İzmir Katip Çelebi University Atatürk Research and Training Hospital Emergency Department with postictal psychiatric symptoms between January 2013 and December 2014, were retrospectively collected.
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Conclusion & Impact:Bonferroni correction was performed for post-hoc analysis.Results: There were no differences in the seizure recurrence rate between benzodiazepine, haloperidol and without medication groups (p>0.05).Conclusion: Our results suggest that benzodiazepines and haloperidol do not affect the development of recurrent seizures when administered for postictal symptoms.
🔬Design:Research Article
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Patients with epilepsy may experience a number of psychiatric and cognitive symptoms or behavioral manifestations during the period of a seizure and the postictal period. The aim of this pilot study was to compare the effects medications commonly used in emergency departments for postictal psychiatric symptoms on seizure recurrence.Methods: Data of 32 epileptic patients, who presented to İzmir Katip Çelebi University Atatürk Research and Training Hospital Emergency Department with postictal psychiatric symptoms between January 2013 and December 2014, were retrospectively collected. Demographic and clinical data were obtained from the emergency department charts and neurology and psychiatry consultation records. Data regarding administered drugs were obtained from the hospital data processing system. The chi-square test, Mann-Whitney U test and the KruskalWallis test were used as statistical methods. Bonferroni correction was performed for post-hoc analysis.Results: There were no differences in the seizure recurrence rate between benzodiazepine, haloperidol and without medication groups (p>0.05).Conclusion: Our results suggest that benzodiazepines and haloperidol do not affect the development of recurrent seizures when administered for postictal symptoms.

Özet

Amaç: Epilepsi hastaları postiktal dönemlerinde psikiyatrik, bilişsel ve davranışsal semptomlar gösterebilirler. Bu pilot çalışmada acil servislerde postiktal semptomlarda sıklıkla kullanılan haloperidol ve benzodiyazepinin nöbet tekrarına etkisinin karşılaştırılması amaçlanmıştır.Yöntemler: Ocak 2013 ve Aralık 2014 arasında İzmir Katip Çelebi Üniversitesi Atatürk Eğitim ve Araştırma Hastanesi Acil Servisi'nde postiktal psikiyatrik semptomlarla başvurmuş 32 hasta hastane veri kayıt sisteminden taranmıştır. Veri olarak elektronik arşivden acil servis hasta kartları, nöroloji ve psikiyatri konsültasyon kayıtları ve elektronik hemşire order bilgileri kullanılmıştır. İstatistiksel yöntem olarak kikare, Mann-Whitney U ve Kruskal-Wallis testi kullanılmıştır. Post-hoc analizlerde Bonferroni düzeltmesi yapılmıştır.Bulgular: Nöbet tekrarı açısından benzodiyazepin, haloperidol ve ilaç kullanılmayan gruplar arasında anlamlı fark saptanmamıştır (p>0,05). Sonuç: Postiktal psikiyatrik semptomlarda benzodiyazepin ve haloperidolün nöbet tekrarına anlamlı bir etkisi olmadığı saptanmıştır.

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Cite This Article

KARA, P. H., ÜNLÜER, E. E. (2017). Comparison of the Effects of Haloperidol and Benzodiazepines Used for Postictal Psychiatric Symptoms on Seizure Recurrence: A Pilot Study. Haseki Tıp Bülteni, Cilt: 55 - Sayı: 3, 175–180. https://ajindex.com/articles/267813

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