Journals / Haseki Tıp Bülteni / 2020 / Cilt: 58 - Sayı: 1

Epidemiology, Diagnosis and Treatment of Acute Septic Arthritis in Haseki Orthopedics and Traumatology Clinic

Haseki Ortopedi ve Travmatoloji Kliniği’ndeki Akut Septik Artrit Epidemiyolojisi, Tanı ve Tedavi Yönetimi

Pages
21–26
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Serial needle aspiration, drainage and empirical antibiotherapy should be kept in mind in the treatment of septic arthritis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Septic arthritis may represent a direct invasion of joint space by various microorganisms.
📊
Key Findings & Data:Methods: Thirty-four patients diagnosed with septic arthritis between June 2008 and December 2014 were retrospectively evaluated.
💡
Conclusion & Impact:Serial needle aspiration, drainage and empirical antibiotherapy should be kept in mind in the treatment of septic arthritis.
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Septic arthritis may represent a direct invasion of joint space by various microorganisms. The aim of this study was to determine the epidemiological characteristics of patients with septic arthritis in our clinic and to discuss the diagnosis, treatment and management. Methods: Thirty-four patients diagnosed with septic arthritis between June 2008 and December 2014 were retrospectively evaluated. Clinical and epidemiological characteristics of the patients, microorganisms causing infection and treatment choice were analyzed. Results: Most patients were male (55.9%) and the mean age of the patients was 42.8 (1-87) years. The knee was the most often affected joint (91.6%). Fever was present in only 17.6% of the cases. Gram staining was positive in only 17.6% of the synovial fluid samples analyzed. Among the 34 patients studied, 10 had positive synovial fluid culture (29.4%). Staphylococcus aureus was the most common pathogen. Conclusion: Gram negative staining, absence of fever and normal leukocyte count do not rule out septic arthritis but only reduce the possibility. Samples should be taken prior to antibiotic treatment to avoid false negative detection of positive samples. Serial needle aspiration, drainage and empirical antibiotherapy should be kept in mind in the treatment of septic arthritis.

Özet

Amaç: Septik artrit, mikroorganizmalar tarafından doğrudan eklem boşluğunun invazyonu şeklinde temsil edilebilir. Çalışmamızın amacı kliniğimizde septik artrit tanısı almış olan hastaların epidemiyolojik özelliklerini ortaya koymak, tanı ve tedavi yönetimini tartışmaktır. Yöntemler: Haziran 2008 ile Aralık 2014 tarihleri arasında septik artrit tanısı almış 34 hasta retrospektif olarak tarandı. Hastaların klinik ve epidemiyolojik özellikleri, enfeksiyona sebep olan mikroorganizmalar ve tedavi seçimi analiz edildi. Bulgular: Hastaların çoğunluğu erkek (%55,9) olup ortalama yaş 42,8 idi (1-87). Diz, en sık tutulan eklemdi (%91,6). Hastaların sadece %17,6’sında ateş saptandı. Analiz edilen sinoviyal sıvı örneklerinin sadece %1,6’sında gram boyama pozitif saptandı. Çalışmaya dahil olan 34 hastanın 10’unda pozitif sinoviyal sıvı kültürü mevcuttu (%29,4). Staphylococcus aureus en sık saptanan mikroorganizmaydı. Sonuç: Gram boyama negatifliği, ateşin olmaması ve normal lökosit sayısı septik artrit tanısını dışlatmaz ancak sadece olasılığını azaltır. Örnekler, kültür negatifliği ve negatif gram boyamayı önlemek adına antibiyotik tedavisinden önce alınmalıdır. Tekrarlayan iğne aspirasyon, drenaj ve ampirik antibiyoterapi septik artrit tedavisinde akılda tutulmalıdır.

🔖

Cite This Article

YILDIRIM, C., MUSLU, D. C., MURATOĞLU, O. G., ORDU, S., AYDIN, Ö. A., BAYRAM, E. (2020). Epidemiology, Diagnosis and Treatment of Acute Septic Arthritis in Haseki Orthopedics and Traumatology Clinic. Haseki Tıp Bülteni, Cilt: 58 - Sayı: 1, 21–26. https://ajindex.com/articles/267785

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Ross JJ. Septic arthritis. Infect Dis Clin North Am 2005;19:799-817.
  2. Dlabach JA, Park AL. Infectious Arthritis. In: Canale ST, Beaty JH, editors. Campbell’s Operative Orthopaedics. 11th edition. Mosby, Philadelphia; 2011:723-7. Tarkowski A. Infection and musculoskeletal conditions: Infectious arthritis. Best Pract Res Clin Rheumatol 2006;20:1029-44.
  3. Smith RL, Schurman DJ, Kajiyama G, Mell M, Gilkerson E. The effect of antibiotics on the destruction of cartilage in experimental infectious arthritis. J Bone Jt Surg 1987;69:1063-8.
  4. Shirtliff ME, Mader JT. Acute septic arthritis. Clin Microbiol Rev 2002;15:527-44.
  5. Molloy A, Laing A, O’Shea K, Bell L, O’Rourke K. The complications of septic arthritis in the elderly. Aging Clin Exp Res 2010;22:270-3.
  6. Williams RJ, Laurencin CT, Warren RF. Septic arthritis after arthroscopic anterior cruciate ligament reconstruction. Diagnosis and management. Am J Sports Med 1997;25:261-7. Kaandorp CJ, van Schaardenburg D, Krijnen P, Habbema JD, van de Laar MA. Risk factors for septic arthritis in patients with joint disease: a prospective study. Arthritis Rheum 1995;38:1819-25.
  7. Dubost JJ, Soubrier M, De Champs C, Ristori JM, Bussiere JL, Sauvezie B. No changes in the distribution of organisms responsible for septic arthritis over a 20 year period. Ann Rheum Dis 2002;61:267-9.
  8. Gupta MN, Sturrock RD, Field M. A prospective 2-year study of 75 patients with adult-onset septic arthritis. Rheumatology 2001;40:24-30.
  9. Helito CP, Noffs GG, Pecora JR, et al. Epidemiology of septic arthritis of the knee at Hospital das Clínicas, Universidade de São Paulo. Braz J Infect Dis 2014;18:28-33.
  10. Gupta MN, Sturrock RD, Field M. Prospective comparative study of patients with culture proven and high suspicion of adult onset septic arthritis. Ann Rheum Dis 2003;62:327-31.
  11. Kallio MJT, Unkila-Kallio L, Aalto K. Serum C-reactive protein, erythrocyte sedimentation rate and white blood cell count in septic arthritis of children. Pediatr Infect Dis J 1997;16:411-3.
  12. Kunnamo I, Kallio P, Pelkonen P. Clinical signs and laboratory tests in the differential diagnosis of arthritis in children. Am J Dis Child 1987;141:34-40.
  13. Kortekangas P, Aro HT, Tuominen J. Synovial fluid leukocytosis in bacterial arthritis vs. reactive arthritis and rheumatoid arthritis in the adult knee. Scand J Rheumatol 1992;21:283-8.
  14. Li SF, Henderson J, Dickman E, Darzynkiewicz R. Laboratory tests in adults with monoarticular arthritis: can they rule out a septic joint? Acad Emerg Med 2004;1