Journals / Haseki Tıp Bülteni / 2021 / Cilt: 59 - Sayı: 2

Relationship Between Clinical Disease Characteristics and Acute and Structural Changes in Sacroiliac Magnetic Resonance Imaging in Patients with Newly Diagnosed Axial Spondyloarthritis

Pages
152–158
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Clinical and laboratory characteristics in axSpA patients are associated with chronic structural lesions rather than inflammation signs in SIJ MRI.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The association between acute and structural lesions on magnetic resonance imaging (MRI) of the sacroiliac joint (SIJ) with clinical and laboratory features has not been fully investigated.
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Key Findings & Data:Methods: Eighty four patients diagnosed with axSpA between June 2019 and June 2020 were retrospectively examined.
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Conclusion & Impact:Conclusion: Clinical and laboratory characteristics in axSpA patients are associated with chronic structural lesions rather than inflammation signs in SIJ MRI.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Özet

Aim: The association between acute and structural lesions on magnetic resonance imaging (MRI) of the sacroiliac joint (SIJ) with clinical and laboratory features has not been fully investigated. This study aimed to compare the clinical and laboratory features of patients diagnosed with axial spondyloarthritis (axSpA) with and without inflammation or structural lesions in SIJ MRI. Methods: Eighty four patients diagnosed with axSpA between June 2019 and June 2020 were retrospectively examined. Patients’ medical records, laboratory data and MRI findings were collected. Inflammation was measured by C-reactive protein levels and erythrocyte sedimentation rate (ESR) (Westergren method, 0-20 mm/h). Moreover, the Spondyloarthritis Research Consortium of Canada MRI index was used to assess inflammation and structural changes of the SIJ. Results: ESR values were statistically significantly different in patients with SIJ backfill and ankylosis (p=0.013 and p=0.016, respectively) and symptom duration in patients with SIJ erosion and ankylosis (p=0.048 and p=0.049, respectively) compared to those without. Morning stiffness was the only IBP characteristic which had a significant correlation with the presence of SIJ ankylosis (p=0.048, r=- 0.218). Conclusion: Clinical and laboratory characteristics in axSpA patients are associated with chronic structural lesions rather than inflammation signs in SIJ MRI.

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Cite This Article

ÇORUM, M., AYDIN, T. (2021). Relationship Between Clinical Disease Characteristics and Acute and Structural Changes in Sacroiliac Magnetic Resonance Imaging in Patients with Newly Diagnosed Axial Spondyloarthritis. Haseki Tıp Bülteni, Cilt: 59 - Sayı: 2, 152–158. https://ajindex.com/articles/267754

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References (12)

  1. Cakır N, Pamuk ÖN, Derviş E, et al. The prevalences of some rheumatic diseases in western Turkey: Havsa study. Rheumatol Int 2012;32:895-908
  2. Baraliakos X, Tsiami S, Redeker I, et al. Early recognition of patients with axial spondyloarthritis-evaluation of referral strategies in primary care. Rheumatology (Oxford) 2020;59:3845-52
  3. Gökşenoğlu G, Buğdaycı D, Paker N, Yıldırım MA, Etli Ö. The prevalence of comorbidity and predictors in ankylosing spondylitis. Turk J Phys Med Rehabil 2018;65:132-8. 4. van Hoeven L, Luime J, Han H, Vergouwe Y, Weel A. Identifying axial spondyloarthritis in Dutch primary care patients, ages 20-45 years, with chronic low back pain. Arthritis Care Res (Hoboken) 2014;66:446-53
  4. Masson Behar V, Dougados M, Etcheto A, et al. Diagnostic delay in axial spondyloarthritis: A cross-sectional study of 432 patients. Joint Bone Spine 2017;84:467-71
  5. Sieper J, Rudwaleit M, Baraliakos X, et al. The Assessment of SpondyloArthritis international Society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis 2009;68:1- 44
  6. Protopopov M, Sieper J, Haibel H, Listing J, Rudwaleit M, Poddubnyy D. Relevance of structural damage in the sacroiliac joints for the functional status and spinal mobility in patients with axial spondyloarthritis: results from the German Spondyloarthritis Inception Cohort. Arthritis Res Ther 2017;19:240
  7. Iaremenko O, Shynkaruk I, Fedkov D, Iaremenko K, Petelytska L. Bone turnover biomarkers, disease activity, and MRI changes of sacroiliac joints in patients with spondyloarthritis. Rheumatol Int 2020;40:2057-63
  8. Schwartzman M, Maksymowych WP. Is There a Role for MRI to Establish Treatment Indications and Effectively Monitor Response in Patients with Axial Spondyloarthritis? Rheum Dis Clin North Am 2019;45:341-58
  9. Rudwaleit M, Jurik AG, Hermann KG, et al. Defining active sacroiliitis on magnetic resonance imaging (MRI) for classification of axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI group. Ann Rheum Dis 2009;68:1520-7
  10. Mandl P, Navarro-Compán V, Terslev L, et al. EULAR recommendations for the use of imaging in the diagnosis and management of spondyloarthritis in clinical practice. Ann Rheum Dis 2015;74:1327-39
  11. Rudwaleit M, Metter A, Listing J, Sieper J, Braun J. Inflammatory back pain in ankylosing spondylitis: a reassessment of the clinical history for application as classification and diagnostic criteria. Arthritis Rheum 2006;54:569-78
  12. Weisman M