Journals / Sakarya Tıp Dergisi / 2019 / Cilt: 9 - Sayı: 2

Testicular non-metastatic paraganglioma: the first case report

Testiküler metastatik olmayan paraganglioma: ilk olgu

Pages
361–365
Publication Date
2019-06-28
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Subsequent whole body-computerized tomography examinations revealed no suspicious lymph node or metastatic focus.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Paragangliomas are tumors that develop from neural crest cells spread by the sympathoadrenergic neuroendocrine system.
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Key Findings & Data:A 60 years old male patient presented to our clinic with painless right scrotal mass.
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Conclusion & Impact:Subsequent whole body-computerized tomography examinations revealed no suspicious lymph node or metastatic focus.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Paraganglioma · testiküler paraganglioma · testis

Abstract

Paragangliomas are tumors that develop from neural crest cells spread by the sympathoadrenergic neuroendocrine system. Our case is a testicular paraganglioma located exculisively in the testis and it is the first benign case in the English literature. A 60 years old male patient presented to our clinic with painless right scrotal mass. Preoperative scrotal ultrasound revealed a vascularized, mass lesion with two lobules completely filling the middle and lower right testis, measuring 40x24 mm in which anechoic cystic areas were observed. The patient then underwent right radical inguinal orchiectomy. Histopathologically and immunohistochemically, the diagnosis was testicular paraganglioma. Subsequent whole body-computerized tomography examinations revealed no suspicious lymph node or metastatic focus.

Özet

Paragangliomalar sempatoadrenal nöroendokrin sistemin yayıldığı nöral krest hücrelerinden gelişen tümörlerdir. Bizim olgumuz da sadece testis yerleşimli bir paraganglioma olgusu olup, benign vasıftaki literatürdeki ilk olgudur. 60 yaşında erkek hasta, ağrısız, sağ skrotal kitle şikayeti ile kliniğimize başvurdu. Preoperatif skrotal ultrasonda sağ testis orta ve alt polünü tamamen dolduran 40x24 mm boyutlarında kitle lezyonu izlendi. Hastaya sağ radikal orşiektomi uygulandı. Histopatolojik ve immünohistokimyasal inceleme sonucu testiküler paraganglioma tanısı konuldu. Ardından yapılan tüm vücut bilgisayarlı tomografi incelemelerinde herhangi bir şüpheli lenf noduna veya metastatik odağa rastlanmadı.

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Cite This Article

ŞENEL, S., BULUT, S., ÖZDEN, C. (2019). Testicular non-metastatic paraganglioma: the first case report. Sakarya Tıp Dergisi, Cilt: 9 - Sayı: 2, 361–365. https://ajindex.com/articles/261811

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References (10)

  1. Erickson D, Kudva YC, Ebersold MJ, Thompson GB, Grant CS,vanHeerden JA, Young WF Jr (2001) Extra adrenal paragangliomas of the sympathoadrenal neuroendocrine system. In: Lack EE, ed. Atlas of Tumor Pathology, Tumors of the Adrenal Gland and Extra Adrenal Paraganglia. 3rd ed. Bethesda, Md: Armed Forces Institute of Pathology; 1997:269–284. Lee JA and Duh QY. Sporadic paraganglioma. World J Surg 2008; 32: 683-687.
  2. DeVita VT, Hellman S Jr, Rosenborg SA. Cancer Principles and Practice of Oncology. Chapter 29: 841- 847, 2003.
  3. Eusebi V, Massarelli G (1971) Phaeochromocytoma of the spermatic cord: report of a case. J Pathol 105(4):283–284
  4. Soejima H, Ogawa O, Nomura Y, Ogata J (1977) Pheochromocytoma of the spermatic cord: a case report. J Urol 118(3):495–496
  5. Bacchi CE, Schmidt RA, Brandao M, Scapulatempo R, Costa JC, Schmitt FC (1990) Paraganglioma of the spermatic cord. Report of a case with immunohistochemical and ultrastructural studies. Arch PatholLabMed 114(8):899–901
  6. Mashat F, Meccawi A, Garg S, Christian E (1993) Paraganglioma of the spermatic cord. AnnSaudiMed 13(2):208–210
  7. Attaran SY, Shakeri S, Sobhani AR (1996) Paraganglioma of the spermatic cord: report of a case. J Urol 155(2):651 Young IE, Nawroz IM, Aitken RJ (1999) Phaeochromocytoma of the spermatic cord. J Clin Pathol 52(4):305–306
  8. Abe T, Matsuda H, Shindo J, Nonomura K, Koyanagi T (2000) Ectopic pheochromocytom aarising in the spermatic cord 5 years after removal of bilateral carotid body tumors and adrenal pheochromocytomas. Int J Urol 7(3):110–111
  9. Garaffa G, Muneer A, Freeman A, AbdelRaheem AM, Ralph DJ, Minhas S, Rees RW (2008) Paraganglioma of the spermatic cord: case report and review of the literature. Sci World J 8:1256–1258 VirchowsArch. 2010 Nov;457(5):619-22. doi: 10.1007/s00428-010-0966-9. Epub 2010 Sep15. A non-catecholamine-producing sympathetic paraganglioma of the spermatic cord: the importance of performing candidate gene mutation analysis.Alataki D1, Triantafyllidis A, Gaal J, Rodiou C, Vouros J, Papathanasiou A, Papanicolaou A, Rombis V, de Krijger RR. Peng Xu, Zhichao Huang, YeqiNian, Mou Peng, Zhiguang Zhou, Lu Yi1, Yijian Li, Yinhuai Wang Departments of Urology and Endocrine, The Second XiangyaHospital, Central South University, Changsha, Hunan, China. Equal contributors. Case Report Malignant paraganglioma of testis and spermatic cord: a case report. Int J ClinExpMed 2017;10(10):14851-14855
  10. Makris MC, Koumarelas KC, Mitrousias AS, Psathas GG, Mantzioros A, Sakellariou