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Journals / Sakarya Tıp Dergisi / 2020 / Cilt: 10 - Sayı: 3

Is there any association between the monocyte / lymphocyte ratio and the presence and severity of the disease in patients with psoriasis? A cross-sectional study.

Psöriazis hastalarında monosit / lenfosit oranı ile hastalığın varlığı ve şiddeti arasında bir ilişki var mıdır? Kesitsel bir çalışma.

Nur Cihan COŞANSU
Bahar SEVİMLİ DİKİCİER
Mahizar YALDİZ
Berna SOLAK
Pages
430–436
Publication Date
2020-09-15
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Patients with psoriasis had higher leukocyte, neutrophil, monocyte counts and MLR compared with control group (p=0.003, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Patients with psoriasis have increased systemic inflammation and monocytes levels compared with the general population.
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Key Findings & Data:Materials and Methods: A total of 180 consecutive patients who had been routinely referred to psoriasis outpatient clinic,and 40 healthy individuals were included in our case-control study between January 2015, and January 2017.
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Conclusion & Impact:Results: Patients with psoriasis had higher leukocyte, neutrophil, monocyte counts and MLR compared with control group (p=0.003, p
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:inflamasyon · psöriazis · monosit

Abstract

Objective: Patients with psoriasis have increased systemic inflammation and monocytes levels compared with the general population. However, the role of monocytes in modulating inflammation in these patients is not clearly known. Psoriasis patients, where inflammation plays a role, are also at risk for cardiovascular diseases. The monocyte-to-lymphocyte ratio (MLR) may reflect a systemic inflammatory status. The aim of this study was to investigate the usefulness of MLR in patients with psoriasis. Materials and Methods: A total of 180 consecutive patients who had been routinely referred to psoriasis outpatient clinic,and 40 healthy individuals were included in our case-control study between January 2015, and January 2017. Demographic features, Psoriasis Area and Severity Index (PASI) scores,and laboratory data were collected from electronic database system. Results: Patients with psoriasis had higher leukocyte, neutrophil, monocyte counts and MLR compared with control group (p=0.003, p

Özet

Amaç: Psöriyazis’li hastalar, genel popülasyona kıyasla artmış sistemik inflamasyon ve monosit seviyelerine sahiptir. Bununla birlikte, bu hastalarda monositlerin enflamasyonu modüle etmedeki rolü açıkça bilinmemektedir. Enflamasyonun rol oynadığı psöriyazis hastaları kardiyovasküler hastalıklar içinde risk altındadır. Monosit-lenfosit oranı (MLO) sistemik bir enflamatuar durumu yansıtabilir. Bu çalışmanın amacı psöriyazis hastalarında MLO'nın yararlılığını araştırmaktır. Gereç ve Yöntemler: Vaka-kontrol çalışmamıza Ocak 2015 ile Ocak 2017 arasında psöriyazis polikliniğine rutin olarak yönlendirilen toplam 180 ardışık hasta ve 40 sağlıklı birey dahil edildi. Demografik özellikler, Psöriyazis Alan ve Şiddet İndeksi (PASI) skorları ve laboratuvar verileri elektronik veri tabanı sisteminden toplandı. Bulgular: Psöriyazis hastalarında kontrol grubuna kıyasla daha yüksek lökosit, nötrofil, monosit sayısı ve MLO vardı (sırasıyla p = 0.003, p

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Cite This Article

COŞANSU, N. C., DİKİCİER, B. S., YALDİZ, M., SOLAK, B. (2020). Is there any association between the monocyte / lymphocyte ratio and the presence and severity of the disease in patients with psoriasis? A cross-sectional study.. Sakarya Tıp Dergisi, Cilt: 10 - Sayı: 3, 430–436. https://ajindex.com/articles/261568

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